Zobrazeno 1 - 10
of 885
pro vyhledávání: '"Alfonso T"'
Autor:
Vera M. S. Isca, Gabrielle Bangay, Salvatore Princiotto, Lucília Saraíva, Daniel J. V. A. dos Santos, Alfonso T. García-Sosa, Patrícia Rijo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Protein kinase C is a family of kinases that play important roles in carcinogenesis. Medicinal plants from Plectranthus spp. (Lamiaceae) are a well-known source of interesting abietanes, such as 7α-acetoxy-6β-hydroxyroyleanone (Roy). This
Externí odkaz:
https://doaj.org/article/bb2ce814416a4a93a98fc9bfbad18360
Autor:
Tereza Hofmanova, Carolina Marques, Alfonso T. García-Sosa, Óscar López, Luisa Leitzbach, Elisabete P. Carreiro, Aday González-Bakker, Adrián Puerta, Holger Stark, José M. Padrón, José G. Fernández-Bolaños, Anthony J. Burke
Publikováno v:
Results in Chemistry, Vol 6, Iss , Pp 101032- (2023)
The oxindole core is an important structural motif in many natural and synthetic substances with various biological activities including anticancer, antineurodegenerative, and antimicrobial properties. This report focuses on the synthesis and biologi
Externí odkaz:
https://doaj.org/article/75d359ef21d247a498f7e6bdb867b7b7
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-3 (2023)
Abstract The urgency of finding therapeutic solutions for emerging and existing health challenges has never been more pronounced. In the pursuit of this goal, the value of a strategy that makes use of existing resources is being recognized: drug repu
Externí odkaz:
https://doaj.org/article/c6c1af3df42345dc8810b9b839894010
Publikováno v:
Energies, Vol 16, Iss 13, p 5225 (2023)
The digital revolution requires greater reliability from electric power systems. However, predicting the growth of electricity demand is challenging as there is still much uncertainty in terms of demographics, industry changes, and irregular consumpt
Externí odkaz:
https://doaj.org/article/c0a12a054234407e924112c3df278f0b
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1839 (2023)
The search for new therapeutic targets and their implications in drug development remains an emerging scientific topic. BRCT-bearing proteins are found in Archaea, Bacteria, Eukarya, and viruses. They are traditionally involved in DNA repair, recombi
Externí odkaz:
https://doaj.org/article/dfa1bf99ac2d44aca464f35e3a1b5701
Autor:
Valeria Laynes-Fiascunari, Edgar Gutierrez-Franco, Luis Rabelo, Alfonso T. Sarmiento, Gene Lee
Publikováno v:
Applied Sciences, Vol 13, Iss 10, p 5888 (2023)
The proliferation of e-commerce in recent years has been driven in part by the increasing ease of making purchases online and having them delivered directly to the consumer. However, these last-mile delivery logistics have become complex due to exter
Externí odkaz:
https://doaj.org/article/cc23d8302c0f403ab2846bdc4e951c4d
Publikováno v:
Energies, Vol 16, Iss 6, p 2614 (2023)
An agent-based modeling framework is developed and employed to replicate the interactions among urban farms. The objectives are to efficiently manage an urban farm’s food, energy, and water resources, decrease food waste, and increase the food avai
Externí odkaz:
https://doaj.org/article/74b03d13a58a4cc58acadcfd45f3cda9
Autor:
Petko Alov, Merilin Al Sharif, Denitsa Aluani, Konstantin Chegaev, Jelena Dinic, Aleksandra Divac Rankov, Miguel X. Fernandes, Fabio Fusi, Alfonso T. García-Sosa, Risto Juvonen, Magdalena Kondeva-Burdina, José M. Padrón, Ilza Pajeva, Tania Pencheva, Adrián Puerta, Hannu Raunio, Chiara Riganti, Ivanka Tsakovska, Virginia Tzankova, Yordan Yordanov, Simona Saponara
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Sdox is a hydrogen sulfide (H2S)-releasing doxorubicin effective in P-glycoprotein-overexpressing/doxorubicin-resistant tumor models and not cytotoxic, as the parental drug, in H9c2 cardiomyocytes. The aim of this study was the assessment of Sdox dru
Externí odkaz:
https://doaj.org/article/1c7deddbd8504d1eb6e324f730103fb1
Autor:
Maria Kletecka-Pulker, Himel Mondal, Dongdong Wang, R. Gonzalo Parra, Abdulkadir Yusif Maigoro, Soojin Lee, Tushar Garg, Eoghan J. Mulholland, Hari Prasad Devkota, Bikramjit Konwar, Sourav S. Patnaik, Ronan Lordan, Faisal A. Nawaz, Christos Tsagkaris, Rehab A. Rayan, Anna Maria Louka, Ronita De, Pravin Badhe, Eva Schaden, Harald Willschke, Mathias Maleczek, Hemanth Kumar Boyina, Garba M. Khalid, Md. Sahab Uddin, Sanusi, Johra Khan, Joy I. Odimegwu, Andy Wai Kan Yeung, Faizan Akram, Chandragiri Siva Sai, Sherri Bucher, Shravan Kumar Paswan, Rajeev K. Singla, Bairong Shen, Sara Di Lonardo, Anela Tosevska, Jesus Simal-Gandara, Manja Zec, Elena González-Burgos, Marija Habijan, Maurizio Battino, Francesca Giampieri, Aleksei Tikhonov, Danila Cianciosi, Tamara Y. Forbes-Hernandez, José L. Quiles, Bruno Mezzetti, Smith B. Babiaka, Mosa E.O. Ahmed, Paula Piccard, Mágali S. Urquiza, Jennifer R. Depew, Fabien Schultz, Daniel Sur, Sandeep R. Pai, Mihnea-Alexandru Găman, Merisa Cenanovic, Nikolay T. Tzvetkov, Surya Kant Tripathi, Kiran R. Kharat, Alfonso T. Garcia-Sosa, Simon Sieber, Atanas G. Atanasov
Publikováno v:
Current Research in Biotechnology, Vol 3, Iss , Pp 146-153 (2021)
The open innovation hub Digital Health and Patient Safety Platform (DHPSP) was recently established with the purpose to invigorate collaborative scientific research and the development of new digital products and personalized solutions aiming to impr
Externí odkaz:
https://doaj.org/article/965a7e1b50a24b18b2ad75c2b5f21ad1
Autor:
Larisa Ivanova, Jaana Tammiku-Taul, Alfonso T. García-Sosa, Yulia Sidorova, Mart Saarma, Mati Karelson
Publikováno v:
ACS Omega, Vol 3, Iss 9, Pp 11407-11414 (2018)
Externí odkaz:
https://doaj.org/article/3df9a70d688b422883f8c8149382ba0d