Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Alfonso Serrano‐Del Valle"'
Autor:
Manuel Beltrán‐Visiedo, Nelia Jiménez‐Alduán, Rosana Díez, Marta Cuenca, Andrea Benedi, Alfonso Serrano‐Del Valle, Gemma Azaceta, Luis Palomera, Victor Peperzak, Alberto Anel, Javier Naval, Isabel Marzo
Publikováno v:
Molecular Oncology, Vol 17, Iss 12, Pp 2507-2525 (2023)
A better understanding of multiple myeloma (MM) biology has led to the development of novel therapies. However, MM is still an incurable disease and new pharmacological strategies are needed. Dinaciclib, a multiple cyclin‐dependent kinase (CDK) inh
Externí odkaz:
https://doaj.org/article/597889ddd17c42ce92b6008ca8428ba5
Autor:
Alfonso Serrano Del Valle, Manuel Beltrán-Visiedo, Victoria de Poo-Rodríguez, Nelia Jiménez-Alduán, Gemma Azaceta, Rosana Díez, Beatriz Martínez-Lázaro, Isabel Izquierdo, Luis Palomera, Javier Naval, Alberto Anel, Isabel Marzo
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Immunogenic cell death (ICD) has been proposed to be a crucial process for antitumor immunosurveillance. ICD is characterized by the exposure and emission of Damage Associated Molecular Patterns (DAMP), including calreticulin (CRT). A positive correl
Externí odkaz:
https://doaj.org/article/c49199a3f6714ed998461eab0fbb19a5
Autor:
Jaime García-Prieto, Rocío Villena-Gutiérrez, Mónica Gómez, Esther Bernardo, Andrés Pun-García, Inés García-Lunar, Georgiana Crainiciuc, Rodrigo Fernández-Jiménez, Vinatha Sreeramkumar, Rafael Bourio-Martínez, José M García-Ruiz, Alfonso Serrano del Valle, David Sanz-Rosa, Gonzalo Pizarro, Antonio Fernández-Ortiz, Andrés Hidalgo, Valentín Fuster, Borja Ibanez
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Metoprolol is a selective β1 adrenergic receptor blocker that reduces cardiac infarct size and improves cardiac function. The drug is believed to act on cardiomyocytes; however, here the authors show that metoprolol exerts its beneficial effect on i
Externí odkaz:
https://doaj.org/article/2b22a5e28d73475c92751f453e8cb4e3
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Externí odkaz:
https://doaj.org/article/6b8d4470e89248c88d1484f11b11fcfe
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Over the past decades, immunotherapy has demonstrated a prominent clinical efficacy in a wide variety of human tumors. For many years, apoptosis has been considered a non-immunogenic or tolerogenic process whereas necrosis or necroptosis has long bee
Externí odkaz:
https://doaj.org/article/5b1d0ae9069f43dab824049eb445a43e
Publikováno v:
Trends in Cancer. 6:518-532
In recent years immunotherapy has provided new hope for cancer patients. However, some patients eventually relapse. Immunological responses are thought to underlie the long-term effects of conventional or targeted therapies. Whether this influence em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd3b23a7a582eff2bcdc1c7e66aec833
https://doi.org/10.1016/j.trecan.2020.02.015
https://doi.org/10.1016/j.trecan.2020.02.015
Autor:
Georgiana Crainiciuc, Miguel Palomino-Segura, Miguel Molina-Moreno, Jon Sicilia, David G. Aragones, Jackson Liang Yao Li, Rodrigo Madurga, José M. Adrover, Alejandra Aroca-Crevillén, Sandra Martin-Salamanca, Alfonso Serrano del Valle, Sandra D. Castillo, Heidi C. E. Welch, Oliver Soehnlein, Mariona Graupera, Fátima Sánchez-Cabo, Alexander Zarbock, Thomas E. Smithgall, Mauro Di Pilato, Thorsten R. Mempel, Pierre-Louis Tharaux, Santiago F. González, Angel Ayuso-Sacido, Lai Guan Ng, Gabriel F. Calvo, Iván González-Díaz, Fernando Díaz-de-María, Andrés Hidalgo
Publikováno v:
DDFV. Repositorio Institucional de la Universidad Francisco de Vitoria
instname
Nature
instname
Nature
Transcriptional and proteomic profiling of individual cells have revolutionized interpretation of biological phenomena by providing cellular landscapes of healthy and diseased tissues1,2. These approaches, however, do not describe dynamic scenarios i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b632ae9c19620d207c528400bbada8f8
http://hdl.handle.net/10641/2967
http://hdl.handle.net/10641/2967
Autor:
Alberto Anel, Andrea Benedi, Isabel Marzo, Javier Naval, Chantal Reina-Ortiz, Alfonso Serrano-del Valle
Publikováno v:
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
instname
Dysregulation of cell cycle progression is a hallmark of cancer cells. In recent years, efforts have been devoted to the development of new therapies that target proteins involved in cell cycle regulation and mitosis. Novel targeted antimitotic drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41a10ccdde445428d3b39ef4a65357d6
https://doi.org/10.1016/j.bcp.2021.114655
https://doi.org/10.1016/j.bcp.2021.114655
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f85882aa2a9053d6f7bc1c9f702f67dd
http://europepmc.org/articles/PMC6890598
http://europepmc.org/articles/PMC6890598
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Over the past decades, immunotherapy has demonstrated a prominent clinical efficacy in a wide variety of human tumors. For many years, apoptosis has been considered a non-immunogenic or tolerogenic process whereas necrosis or necroptosis has long bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2deb6f5b9eb16b9a6dcb0d5e997990be
https://doi.org/10.3389/fcell.2019.00050
https://doi.org/10.3389/fcell.2019.00050