Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Alfonso Santos-Lopez"'
Autor:
Emilia Wedel, Cristina Bernabe-Balas, Manuel Ares-Arroyo, Natalia Montero, Alfonso Santos-Lopez, Didier Mazel, Bruno Gonzalez-Zorn
Publikováno v:
mBio, Vol 14, Iss 3 (2023)
ABSTRACT Plasmids facilitate the vertical and horizontal spread of antimicrobial resistance genes between bacteria. The host range and adaptation of plasmids to new hosts determine their impact on the spread of resistance. In this work, we explore th
Externí odkaz:
https://doaj.org/article/af91a2358575435fb4c38d1fb7e08714
Autor:
Alfonso Santos-Lopez, Christopher W Marshall, Allison L Haas, Caroline Turner, Javier Rasero, Vaughn S Cooper
Publikováno v:
eLife, Vol 10 (2021)
History, chance, and selection are the fundamental factors that drive and constrain evolution. We designed evolution experiments to disentangle and quantify effects of these forces on the evolution of antibiotic resistance. Previously, we showed that
Externí odkaz:
https://doaj.org/article/a885931ec4fa4f99b3d2d8a163af2398
Autor:
Michelle R. Scribner, Alfonso Santos-Lopez, Christopher W. Marshall, Christopher Deitrick, Vaughn S. Cooper
Publikováno v:
mBio, Vol 11, Iss 3 (2020)
ABSTRACT Different species exposed to a common stress may adapt by mutations in shared pathways or in unique systems, depending on how past environments have molded their genomes. Understanding how diverse bacterial pathogens evolve in response to an
Externí odkaz:
https://doaj.org/article/c367e4abe4e54610aefdfd6b506f56bf
Autor:
Alfonso Santos-Lopez, Christopher W Marshall, Michelle R Scribner, Daniel J Snyder, Vaughn S Cooper
Publikováno v:
eLife, Vol 8 (2019)
Bacterial populations vary in their stress tolerance and population structure depending upon whether growth occurs in well-mixed or structured environments. We hypothesized that evolution in biofilms would generate greater genetic diversity than well
Externí odkaz:
https://doaj.org/article/db56ad7aa2894999ba852e451fba3683
Autor:
Erin S. Gloag, Christopher W. Marshall, Daniel Snyder, Gina R. Lewin, Jacob S. Harris, Alfonso Santos-Lopez, Sarah B. Chaney, Marvin Whiteley, Vaughn S. Cooper, Daniel J. Wozniak
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT Opportunistic pathogens establishing new infections experience strong selection to adapt, often favoring mutants that persist. Capturing this initial dynamic is critical for identifying the first adaptations that drive pathogenesis. Here we
Externí odkaz:
https://doaj.org/article/bb09f2057f05467fa4e687b97db7fb56
Autor:
Manuel Ares-Arroyo, Cristina Bernabe-Balas, Alfonso Santos-Lopez, Maria R. Baquero, Kashi N. Prasad, Dolores Cid, Carmen Martin-Espada, Alvaro San Millan, Bruno Gonzalez-Zorn
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
ColE1 plasmids are important vehicles for the spread of antibiotic resistance in the Enterobacteriaceae and Pasteurellaceae families of bacteria. Their monitoring is essential, as they harbor important resistant determinants in humans, animals and th
Externí odkaz:
https://doaj.org/article/47bc02aa4b3a4e18967d9aa4eea94191
Autor:
Alfonso Santos-Lopez, Melissa J Fritz, Jeffrey B Lombardo, Ansen H P Burr, Victoria A Heinrich, Christopher W Marshall, Vaughn S Cooper
Publikováno v:
Evolution, Medicine, and Public Health. 10:266-276
Background and Objectives A key strategy for resolving the antibiotic resistance crisis is the development of new drugs with antimicrobial properties. The engineered cationic antimicrobial peptide WLBU2 (also known as PLG0206) is a promising broad-sp
Publikováno v:
PLoS Biology
PLoS Biology, Vol 19, Iss 7, p e3001308 (2021)
PLoS Biology, Vol 19, Iss 7, p e3001308 (2021)
Mobile genetic elements (MGEs) drive genetic transfers between bacteria using mechanisms that require a physical interaction with the cellular envelope. In the high-priority multidrug-resistant nosocomial pathogens (ESKAPE), the first point of contac
Autor:
Vaughn S. Cooper, Christopher W. Marshall, MJ Fritz, J Lombardo, Alfonso Santos-Lopez, VA Heinrich, Ahp Burr
A key strategy for resolving the antibiotic resistance crisis is the development of new drugs with antimicrobial properties. The engineered cationic antimicrobial peptide WLBU2 (also known as PLG0206) is a promising broad-spectrum antimicrobial compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c568fb678de5bc13a2f89c8d1c202d7e
https://doi.org/10.1101/2020.12.16.423161
https://doi.org/10.1101/2020.12.16.423161