Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Alfonso Rubio-Navarro"'
Autor:
Melania Guerrero-Hue, Mercedes Vallejo-Mudarra, Cristina García-Caballero, Gina Marcela Córdoba-David, Alejandra Palomino-Antolín, Carmen Herencia, Beatriz Vendrell-Casana, Alfonso Rubio-Navarro, Jesús Egido, Luis Miguel Blanco-Colio, Juan Antonio Moreno
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 169, Iss , Pp 115925- (2023)
Background: Rhabdomyolysis is a severe clinical syndrome associated to acute kidney injury (AKI) and chronic kidney disease (CKD). TWEAK/Fn14 signaling axis regulates renal inflammation and tubular cell death. However, the functional role of TWEAK/Fn
Externí odkaz:
https://doaj.org/article/a38a6f4bb8ce421fb7c661f8c5c2adac
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/f0582031a8414957bf5f905c129ba10f
Autor:
Jason Mighty, Alfonso Rubio-Navarro, Cui Shi, Jing Zhou, Miguel Flores-Bellver, Søren Heissel, Onyekwere Onwumere, Linda Einbond, Rajendra Gharbaran, Daniel S. Casper, Alberto Benito-Martin, Stephen Redenti
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2023)
IntroductionDiabetic Retinopathy (DR) is a potentially blinding retinal disorder that develops through the pathogenesis of diabetes. The lack of disease predictors implies a poor prognosis with frequent irreversible retinal damage and vision loss. Ex
Externí odkaz:
https://doaj.org/article/b129fb42bb9a4132a2d3c9daef2b77e0
Autor:
Melania Guerrero-Hue, Alfonso Rubio-Navarro, Ángel Sevillano, Claudia Yuste, Eduardo Gutiérrez, Alejandra Palomino-Antolín, Elena Román, Manuel Praga, Jesús Egido, Juan Antonio Moreno
Publikováno v:
Nefrología, Vol 38, Iss 1, Pp 13-26 (2018)
La hemoglobina y la mioglobina son hemoproteínas que juegan un papel fundamental en el organismo ya que participan en el transporte de oxígeno. Sin embargo, debido a su estructura química, estas moléculas pueden ejercer efectos deletéreos cuando
Externí odkaz:
https://doaj.org/article/07ab050ab12f4b47accfcbbb65b2f559
Autor:
Melania Guerrero-Hue, Alfonso Rubio-Navarro, Ángel Sevillano, Claudia Yuste, Eduardo Gutiérrez, Alejandra Palomino-Antolín, Elena Román, Manuel Praga, Jesús Egido, Juan Antonio Moreno
Publikováno v:
Nefrología (English Edition), Vol 38, Iss 1, Pp 13-26 (2018)
Haemoglobin and myoglobin are haem proteins that play a key role as they help transport oxygen around the body. However, because of their chemical structure, these molecules can exert harmful effects when they are released massively into the bloodstr
Externí odkaz:
https://doaj.org/article/d0b8f204dfc844bf9f3ac017ea81710b
Autor:
Alfonso Rubio-Navarro, Cristina Vázquez-Carballo, Melania Guerrero-Hue, Cristina García-Caballero, Carmen Herencia, Eduardo Gutiérrez, Claudia Yuste, Ángel Sevillano, Manuel Praga, Javier Egea, Pablo Cannata, Isabel Cortegano, Belén de Andrés, María Luisa Gaspar, Susana Cadenas, Patrycja Michalska, Rafael León, Alberto Ortiz, Jesús Egido, Juan Antonio Moreno
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Massive intravascular hemolysis is associated with acute kidney injury (AKI). Nuclear factor erythroid-2-related factor 2 (Nrf2) plays a central role in the defense against oxidative stress by activating the expression of antioxidant proteins. We inv
Externí odkaz:
https://doaj.org/article/db9f163feba548e684515e2a31a59e8a
Autor:
Melania Guerrero-Hue, Sandra Rayego-Mateos, Cristina Vázquez-Carballo, Alejandra Palomino-Antolín, Cristina García-Caballero, Lucas Opazo-Rios, José Luis Morgado-Pascual, Carmen Herencia, Sebastián Mas, Alberto Ortiz, Alfonso Rubio-Navarro, Javier Egea, José Manuel Villalba, Jesús Egido, Juan Antonio Moreno
Publikováno v:
Antioxidants, Vol 10, Iss 1, p 39 (2020)
Chronic kidney disease (CKD) is one of the fastest-growing causes of death and is predicted to become by 2040 the fifth global cause of death. CKD is characterized by increased oxidative stress and chronic inflammation. However, therapies to slow or
Externí odkaz:
https://doaj.org/article/1b7bfe55885f4191b65646457b3e8d96
Autor:
Nayara Panizo, Alfonso Rubio-Navarro, Juan Manuel Amaro-Villalobos, Jesús Egido, Juan Antonio Moreno
Publikováno v:
Kidney & Blood Pressure Research, Vol 40, Iss 5, Pp 520-532 (2015)
Rhabdomyolysis is a syndrome caused by injury to skeletal muscle that usually leads to acute kidney injury (AKI). Rhabdomyolysis has been linked to different conditions, including severe trauma and intense physical exercise. Myoglobin-induced renal t
Externí odkaz:
https://doaj.org/article/4bcfdbe6e35248f581c2366c8ab3b6ea
Autor:
Beatriz Martín-Fernández, Alfonso Rubio-Navarro, Isabel Cortegano, Sandra Ballesteros, Mario Alía, Pablo Cannata-Ortiz, Elena Olivares-Álvaro, Jesús Egido, Belén de Andrés, María Luisa Gaspar, Natalia de Las Heras, Vicente Lahera, Juan Antonio Moreno
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0145946 (2016)
We aimed to evaluate macrophages heterogeneity and structural, functional and inflammatory alterations in rat kidney by aldosterone + salt administration. The effects of treatment with spironolactone on above parameters were also analyzed. Male Wista
Externí odkaz:
https://doaj.org/article/dfb9c71ea3974500b2dbce68e81e124c
Autor:
Claudia Yuste, Alfonso Rubio-Navarro, Daniel Barraca, Inés Aragoncillo, Almudena Vega, Soraya Abad, Alba Santos, Nicolás Macias, Ignacio Mahillo, Eduardo Gutiérrez, Manuel Praga, Jesús Egido, Juan Manuel López-Gómez, Juan Antonio Moreno
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0128575 (2015)
Haematuria has been traditionally considered as a benign hallmark of some glomerular diseases; however new studies show that haematuria may decrease renal function.To determine the influence of haematuria on the rate of chronic kidney disease (CKD) p
Externí odkaz:
https://doaj.org/article/33e5a7d199904677a7ba64b72a5c4a5e