Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alfonso Martinisi"'
Autor:
Zhiva Skachokova, Alfonso Martinisi, Martin Flach, Frederik Sprenger, Yvonne Naegelin, Viviane Steiner-Monard, Marc Sollberger, Andreas U. Monsch, Michel Goedert, Markus Tolnay, David T. Winkler
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-9 (2019)
Abstract Tau is a microtubule stabilizing protein that forms aggregates in Alzheimer’s disease (AD). Tau derived from AD patients’ brains induces tau aggregation in a prion-like manner when injected into susceptible mouse models. Here we investig
Externí odkaz:
https://doaj.org/article/82fce56f28d34a8fb864ea0b8277378e
Autor:
Martin Flach, Cedric Leu, Alfonso Martinisi, Zhiva Skachokova, Stephan Frank, Markus Tolnay, Henning Stahlberg, David T. Winkler
Publikováno v:
Alzheimer's & Dementia. 18:2481-2492
Abnormal tau protein aggregates constitute a hallmark of Alzheimer's disease. The mechanisms underlying the initiation of tau aggregation in sporadic neurodegeneration remain unclear. Here we investigate whether a non-human prion can seed tau aggrega
Autor:
Alfonso Martinisi, Markus Tolnay, David T. Winkler, Frederik Sprenger, Stephan Frank, Martin Flach
Publikováno v:
Brain
Tau is a microtubule stabilizing protein that forms abnormal aggregates in many neurodegenerative disorders, including Alzheimer’s disease. We have previously shown that co-expression of fragmented and full-length tau in P301SxTAU62on tau transgeni
Autor:
Michel Goedert, Yvonne Naegelin, Alfonso Martinisi, Martin Flach, Viviane Steiner-Monard, Markus Tolnay, Frederik Sprenger, Marc Sollberger, Andreas U. Monsch, David T. Winkler, Zhiva Skachokova
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-9 (2019)
Acta Neuropathologica Communications
Acta Neuropathologica Communications
Tau is a microtubule stabilizing protein that forms aggregates in Alzheimer’s disease (AD). Tau derived from AD patients’ brains induces tau aggregation in a prion-like manner when injected into susceptible mouse models. Here we investigated whet