Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Alfonso Gurpide"'
Autor:
Ana Patiño-García, Elizabeth Guruceaga, Maria Pilar Andueza, Marimar Ocón, Jafait Junior Fodop Sokoudjou, Nicolás de Villalonga Zornoza, Gorka Alkorta-Aranburu, Ibon Tamayo Uria, Alfonso Gurpide, Carlos Camps, Eloísa Jantus-Lewintre, Maria Navamuel-Andueza, Miguel F. Sanmamed, Ignacio Melero, Mohamed Elgendy, Juan Pablo Fusco, Javier J. Zulueta, Juan P. de-Torres, Gorka Bastarrika, Luis Seijo, Ruben Pio, Luis M. Montuenga, Mikel Hernáez, Idoia Ochoa, Jose Luis Perez-Gracia
Publikováno v:
EBioMedicine, Vol 102, Iss , Pp 105048- (2024)
Summary: Background: Tobacco is the main risk factor for developing lung cancer. Yet, while some heavy smokers develop lung cancer at a young age, other heavy smokers never develop it, even at an advanced age, suggesting a remarkable variability in t
Externí odkaz:
https://doaj.org/article/325b5d8d436b42f0be4be23054440e34
Autor:
Juan Pablo Fusco, Guillermo Pita, María José Pajares, Maria Pilar Andueza, Ana Patiño‐García, Juan P. de‐Torres, Alfonso Gurpide, Javier Zulueta, Rosario Alonso, Nuria Alvarez, Ruben Pio, Ignacio Melero, Miguel F. Sanmamed, Maria Rodriguez Ruiz, Ignacio Gil‐Bazo, Jose María Lopez‐Picazo, Ciro Casanova, Rebeca Baz Davila, Antonio Agudo, Maria Dolores Lozano, Alvaro Gonzalez, Nuria Sala, Eva Ardanaz, Javier Benitez, Luis Montuenga, Anna Gonzalez‐Neira, Jose Luis Perez‐Gracia
Publikováno v:
Cancer Medicine, Vol 7, Iss 7, Pp 3474-3483 (2018)
Abstract Single nucleotide polymorphisms (SNPs) may modulate individual susceptibility to carcinogens. We designed a genome‐wide association study to characterize individuals presenting extreme phenotypes of high and low risk to develop tobacco‐i
Externí odkaz:
https://doaj.org/article/c3b285810a764be5ae798d81e210d99b
Autor:
Celia Prior, Jose Luis Perez-Gracia, Jesus Garcia-Donas, Cristina Rodriguez-Antona, Elizabeth Guruceaga, Emilio Esteban, Cristina Suarez, Daniel Castellano, Aránzazu González del Alba, Maria Dolores Lozano, Joan Carles, Miguel Angel Climent, Jose Angel Arranz, Enrique Gallardo, Javier Puente, Joaquim Bellmunt, Alfonso Gurpide, Jose Maria Lopez-Picazo, Alvaro Gonzalez Hernandez, Begoña Mellado, Esther Martínez, Fernando Moreno, Albert Font, Alfonso Calvo
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86263 (2014)
To identify tissue microRNAs predictive of sunitinib activity in patients with metastatic renal-cell-carcinoma (MRCC) and to evaluate in vitro their mechanism of action in sunitinib resistance.We screened 673 microRNAs using TaqMan Low-density-Arrays
Externí odkaz:
https://doaj.org/article/93829b422d804bc7841b6e9812135dcd
Autor:
Belen Sadaba, Anabel del Barrio, Miguel Angel Campanero, Jose Ramon Azanza, Almudena Gomez-Guiu, Jose Maria Lopez-Picazo, Salvador Martin Algarra, Francisco Guillén Grimá, Maria Blanco Prieto, Jose Luis Perez-Gracia, Alfonso Gurpide
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89747 (2014)
Palonosetron is a potent second generation 5- hydroxytryptamine-3 selective antagonist which can be administered by either intravenous (IV) or oral routes, but subcutaneous (SC) administration of palonosetron has never been studied, even though it co
Externí odkaz:
https://doaj.org/article/732bd83ce7fe475ebabe0fd50f2fd1e3
Autor:
Esther Redin, Eva M. Garrido-Martin, Karmele Valencia, Miriam Redrado, Jose Luis Solorzano, Rafael Carias, Mirari Echepare, Francisco Exposito, Diego Serrano, Irene Ferrer, Angel Nunez-Buiza, Irati Garmendia, Juana M. García-Pedrero, Alfonso Gurpide, Luis Paz-Ares, Katerina Politi, Luis M. Montuenga, Alfonso Calvo
Publikováno v:
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 17(12)
SCLC is an extremely aggressive subtype of lung cancer without approved targeted therapies. Here we identified YES1 as a novel targetable oncogene driving SCLC maintenance and metastasis.Association between YES1 levels and prognosis was evaluated in
Autor:
Maria Rodriguez Ruiz, Ana Patiño-García, Maria D. Lozano, Jose Luis Perez-Gracia, J.P. Fusco, Ignacio Melero, Marimar Ocón, Carlos E. de Andrea, Alfonso Gurpide, Maria Pilar Andueza, Luis M. Montuenga, Elizabeth Guruceaga, Guillermo Serrano, Ibon Tamayo Uria, Victor Segura, Miguel F. Sanmamed, Rodrigo Sánchez Bayona, María J. Pajares, Alvaro Gonzalez, Anna González-Neira, Ruben Pio, Javier J. Zulueta, Guillermo Pita
Publikováno v:
Transl Lung Cancer Res
Academica-e. Repositorio Institucional de la Universidad Pública de Navarra
instname
Academica-e. Repositorio Institucional de la Universidad Pública de Navarra
instname
Background: tobacco is the main risk factor for developing lung cancer. Yet, some heavy smokers do not develop lung cancer at advanced ages while others develop it at young ages. Here, we assess for the first time the genetic background of these clin
Autor:
Carlos E. de Andrea, Maria D. Lozano, Juan Berto, Alfonso Calvo, Alfonso Gurpide, José I. Echeveste, Jose Carlos Subtil, Marta Abengozar-Muela
Publikováno v:
Cancer Cytopathology. 127:470-480
Background Programmed death-ligand 1 (PD-L1) expression, as assessed by immunohistochemistry (IHC), is used to select patients with non-small cell lung cancer (NSCLC) for anti-programmed cell death protein 1 (PD-1)/PD-L1 therapy. The current study ev
Autor:
Maria E. Rodriguez-Ruiz, Jose Luis Perez-Gracia, Sonia Tejada, Miguel Angel Idoate, Ascensión López-Díaz de Cerio, Angelo Porciuncula, Jaime Gállego Pérez-Larraya, Jungmin Choi, Susana Inogés, Alvaro López-Janeiro, Ignacio Melero, Carlos E. de Andrea, Franz Villarroel-Espindola, Miguel F. Sanmamed, Pedro Berraondo, Miriam Giráldez, Kurt A. Schalper, Ricardo Díez-Valle, Alfonso Gurpide, Iosune Goicoechea
Publikováno v:
Nature Medicine. 25:470-476
Glioblastoma is the most common primary central nervous system malignancy and has a poor prognosis. Standard first-line treatment, which includes surgery followed by adjuvant radio-chemotherapy, produces only modest benefits to survival1,2. Here, to
Autor:
M. Rodriguez-Remirez, V. Catalan, Jose Luis Perez-Gracia, Alfonso Gurpide, G. Fruhbeck, Ignacio Gil-Bazo, Daniel Ajona, A. Puyalto, Iosune Baraibar, Maria Pilar Andueza, Ruben Pio, Jesus Corral, José María López-Picazo, I. Lopez-Erdozain, A. Vilalta-Lacarra
Publikováno v:
Journal of Thoracic Oncology. 16:S1007-S1008
Publikováno v:
Regular and young investigator award abstracts.
Background Individual susceptibility to carcinogens may depend on genetic background. We performed for the first-time Whole Exome Sequencing (WES) of germline DNA from individuals presenting phenotypes of extreme sensitivity and resistance to develop