Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Alfonso G Scicli"'
Autor:
Branislava Janic, Austin M Guo, A S M Iskander, Nadimpalli Ravi S Varma, Alfonso G Scicli, Ali S Arbab
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9173 (2010)
Stem cells/progenitors are central to the development of cell therapy approaches for vascular ischemic diseases. The crucial step in rescuing tissues from ischemia is improvement of vascularization that can be achieved by promoting neovascularization
Externí odkaz:
https://doaj.org/article/c070b3aaa56b4c80b2d30ddc2d08d605
Autor:
Bhagelu R. Achyut, Ali S. Arbab, Kartik Angara, Alfonso G. Scicli, Peng Zeng, Robert A. Knight, Roxan Ara, Adarsh Shankar, A. S.M. Iskander
Publikováno v:
Cancer Letters. 369:416-426
Glioblastoma (GBM) is a hypervascular and malignant form of brain tumors. Anti-angiogenic therapies (AAT) were used as an adjuvant against VEGF-VEGFR pathway to normalize blood vessels in clinical and preclinical studies, which resulted into marked h
Autor:
Li Chen, Fank F Zhang, Katherine H Gotlinger, John C Falck, Alfonso G Scicli, Michal L Schwartzman, Austin M Guo
Publikováno v:
Hypertension. 64
Objective: Compensatory neovascularizaiton is an important adaptation for recovery from critical ischemia. Recent studies identified the CYP4A-20-HETE system as a novel regulator of angiogenic processes. Here, we assessed the contribution of the 20-H
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 109(3):466-472
Mechanical function and coronary hemodynamics were assessed in 73 isolated rabbit hearts randomly subjected to 0, 10, 20, 30, or 45 minutes of 37 degrees C global ischemia and 45 minutes of reperfusion in either a modified Krebs buffer or homologous
Autor:
Ali S. Arbab, Adarsh Shankar, Bhagelu R. Achyut, Asm Iskander, Robert A. Knight, Alfonso G. Scicli, Roxan Ara, Kartik Angara
Publikováno v:
Cancer Research. 75:A23-A23
Glioblastoma (GBM) is considered as hypervascular form of brain tumors. Anti-angiogenic therapies (AAT) were used as an adjuvant against VEGF-VEGFR pathway to normalize blood vessels. Surprisingly, AAT resulted into marked hypoxia and recruited bone
Publikováno v:
Hypertension. 23:865-868
We examined the effect of non-antihypertensive doses of the angiotensin-converting enzyme inhibitor ramipril, kinins, and/or nitric oxide on left ventricular hypertrophy in rats with aortic coarctation. We investigated the effect of either HOE 140, a
Publikováno v:
Hypertension. 23:919-923
It has been reported that kinins mediate part of the beneficial cardiac effects induced by treatment with angiotensin-converting enzyme inhibitors in situations such as ischemia-reperfusion injury, myocardial infarction, and cardiac hypertrophy. Howe
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 265:H1209-H1214
Vascular tissue contains kallikrein and kallikrein mRNA, suggesting a vascular kallikrein-kinin system. We questioned whether 1) kallikrein concentration varies among large and small vessels; 2) kallikrein is released by vascular tissue; and 3) block
Autor:
Nadimpalli Ravi S. Varma, Branislava Janic, Ali S. Arbab, Austin M. Guo, A. S. M. Iskander, Alfonso G. Scicli
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 2, p e9173 (2010)
PLoS ONE, Vol 5, Iss 2, p e9173 (2010)
Background Stem cells/progenitors are central to the development of cell therapy approaches for vascular ischemic diseases. The crucial step in rescuing tissues from ischemia is improvement of vascularization that can be achieved by promoting neovasc
Autor:
O A Carretero, Alfonso G. Scicli
Publikováno v:
Hypertension. 18:366-371
Inhibitors of two zinc metallopeptidases, angiotensin I converting enzyme (ACE) and neutral metalloendopeptidase-24.11 (EP-24.11), are antihypertensive agents. In this issue of Hypertension, Genden and Molineaux report that yet another peptidase inhi