Gold-Coated Superparamagnetic Nanoparticles for Single Methyl Discrimination in DNA Aptamers

Autor: Maria Tintoré, Stefania Mazzini, Laura Polito, Marcello Marelli, Alfonso Latorre, Álvaro Somoza, Anna Aviñó, Carme Fàbrega, Ramon Eritja

Publikováno v: International Journal of Molecular Sciences, Vol 16, Iss 11, Pp 27625-27639 (2015)

Au- and iron-based magnetic nanoparticles (NPs) are promising NPs for biomedical applications due to their unique properties. The combination of a gold coating over a magnetic core puts together the benefits from adding the magnetic properties to the

Externí odkaz: https://doaj.org/article/e3ad694ed3e243d9b650a9e2bef04349

Albumin-based nanostructures for uveal melanoma treatment

Autor: Nuria Lafuente-Gómez, Marco Cordani, Pilar Martin-Duque, Alejandra Crespo-Barreda, Ana Latorre, Álvaro Somoza, Alfonso Latorre, Milagros Castellanos, Ciro Rodriguez Diaz, Mercedes Lecea

Publikováno v: Repositorio Institucional del Instituto Madrileño de Estudios Avanzados en Nanociencia
instname

Uveal melanoma (UM) is an intraocular tumor which is almost lethal at the metastatic stage due to the lack of effective treatments. In this regard, we have developed an albumin-based nanostructure (ABN) containing AZD8055 (ABN-AZD), which is a potent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28dd4309db4ff90d2307e461e76be7d6
http://hdl.handle.net/20.500.12614/2610

Tailored Functionalized Magnetic Nanoparticles to Target Breast Cancer Cells Including Cancer Stem-Like Cells

Autor: Rodolfo Miranda, Álvaro Somoza, Robert Clarke, Ana Lazaro-Carrillo, Macarena Calero, Alfonso Latorre, Aitziber L. Cortajarena, Bruno M Simões, Angeles Villanueva, Antonio Aires

Publikováno v: Cancers
Volume 12
Issue 6
Lazaro-Carrillo, A, Calero, M, Aires, A, L Cortajarena, A, Simões, B M, Latorre, A, Somoza, Á, Clarke, R B, Miranda, R & Villanueva, A 2020, ' Tailored Functionalized Magnetic Nanoparticles to Target Breast Cancer Cells Including Cancer Stem-Like Cells ', Cancers, vol. 12, no. 6 . https://doi.org/10.3390/cancers12061397
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Repositorio Institucional del Instituto Madrileño de Estudios Avanzados en Nanociencia
Cancers, Vol 12, Iss 1397, p 1397 (2020)

Nanotechnology-based approaches hold substantial potential to avoid chemoresistance and minimize side effects. In this work, we have used biocompatible iron oxide magnetic nanoparticles (MNPs) called MF66 and functionalized with the antineoplastic dr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::161dd75c6c53e844a186b9cf02b5a903
http://europepmc.org/articles/PMC7352336

The phenotype of target pancreatic cancer cells influences cell death by magnetic hyperthermia with nanoparticles carrying gemicitabine and the pseudo-peptide NucAnt

Autor: Pierre Couleaud, Yuri Volkov, Adriele Prina-Mello, Alfonso Latorre, José Courty, Mourad Sanhaji, Julia Göring, Álvaro Somoza, Aitziber L. Cortajarena, Rodolfo Miranda, Ingrid Hilger, Marcus Stapf, Robert Ludwig, Antonio Aires

Publikováno v: Nanomedicine: Nanotechnology, Biology and Medicine
Nanomedicine: Nanotechnology, Biology and Medicine, Elsevier, 2019, 20, pp.101983. ⟨10.1016/j.nano.2018.12.019⟩
Repositorio Institucional del Instituto Madrileño de Estudios Avanzados en Nanociencia
instname

International audience; In this paper we show that conjugation of magnetic nanoparticles (MNPs) with Gemcitabine and/or NucAnt (N6L) fostered their internalization into pancreatic tumor cells and that the coupling procedure did not alter the cytotoxi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51f764a59e7d4c3b3de935acd4839377
https://hal.archives-ouvertes.fr/hal-03095445

Chemotherapeutic Drug Functionalized Nanoparticles are Beneficial When Treating Breast Cancer Via Magnetic Hyperthermia

Autor: Ingrid Hilger, Rodolfo Miranda, Alfonso Latorre, Julia Göring, José Courty, Pierre Couleaud, Álvaro Somoza, Aitziber L. Cortajarena, Julia Grandke, Susann Piehler, Heidi Dähring, Antonio Aires

Doxorubicin (DOX) is a frequently used chemotherapeutic drug for breast cancer, but its site specificity and local internalization into tumor cells is rather low. In this paper we conjugated magnetic nanoparticles (MNPs) with DOX and/or a pseudopepti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed857b2f6bea06121e0f8378a1e2cf39