Zobrazeno 1 - 10
of 249
pro vyhledávání: '"Alfonso, Buil"'
Autor:
Joeri Meijsen, Kejia Hu, Morten D. Krebs, Georgios Athanasiadis, Sarah Washbrook, Richard Zetterberg, Raquel Nogueira Avelar e Silva, John R. Shorter, Jesper R. Gådin, Jacob Bergstedt, David M. Howard, Weimin Ye, Yi Lu, Unnur A. Valdimarsdóttir, Andrés Ingason, Dorte Helenius, Oleguer Plana-Ripoll, John J. McGrath, Nadia Micali, Ole A. Andreassen, Thomas M. Werge, Fang Fang, Alfonso Buil
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Mental disorders are leading causes of disability and premature death worldwide, partly due to high comorbidity with cardiometabolic disorders. Reasons for this comorbidity are still poorly understood. We leverage nation-wide health records
Externí odkaz:
https://doaj.org/article/b590855b0172469c974a0c55e5a42e1d
Autor:
Banasik, Karina, Bay, Jakob, Kjærgaard Boldsen, Jens, Brodersen, Thorsten, Brunak, Søren, Demur, Alfonso Buil, Nordahl Christoffersen, Lea Arregui, Didriksen, Maria, Dinh, Khoa Manh, Dowsett, Joseph, Erikstrup, Christian, Feenstra, Bjarke, Geller, Frank, Gudbjartsson, Daniel, Hansen, Thomas Folkmann, Mikkelsen, Dorte Helenius, Hindhede, Lotte, Hjalgrim, Henrik, von Stemann, Jakob Hjorth, Jensen, Bitten Aagaard, Schork, Andrew Joseph, Kaspersen, Kathrine, Kjerulff, Bertram Dalskov, Kongstad, Mette, Mikkelsen, Susan, Mikkelsen, Christina, Nissen, Janna, Nyegaard, Mette, Ostrowski, Sisse Rye, Pedersen, Ole Birger, Elgaard Quinn, Liam James, Rafnar, Þórunn, Rohde, Palle Duun, Rostgaard, Klaus, Schwinn, Michael, Sørensen, Erik, Stefansson, Kari, Stefánsson, Hreinn, Thørner, Lise Wegner, Þorsteinsdóttir, Unnur, Bruun, Mie Topholm, Ullum, Henrik, Werge, Thomas, Westergaard, David, Nudel, Ron, Chrsitensen, Rikke Vang, Kalnak, Nelli, Lundberg, Mischa, Christoffersen, Lea Arregui Nordahl, Burgdorf, Kristoffer Sølvsten, Pedersen, Ole Birger Vesterager, Gísladóttir, Rósa S., Walters, G. Bragi
Publikováno v:
In Psychiatry Research December 2024 342
Publikováno v:
European Journal of Medical Research, Vol 28, Iss 1, Pp 1-14 (2023)
Abstract Background For decades, the basic treatment strategies of necrotizing soft tissue infections (NSTI) have remained unchanged, primarily relying on aggressive surgical removal of infected tissue, broad-spectrum antibiotics, and supportive inte
Externí odkaz:
https://doaj.org/article/1774862a0deb4d9f8ade682396d76f1f
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 15, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/483c0456439f4e73aed157e211952282
Autor:
Vivek Appadurai, Jonas Bybjerg-Grauholm, Morten Dybdahl Krebs, Anders Rosengren, Alfonso Buil, Andrés Ingason, Ole Mors, Anders D. Børglum, David M. Hougaard, Merete Nordentoft, Preben B. Mortensen, Olivier Delaneau, Thomas Werge, Andrew J. Schork
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
An analysis of phasing and imputation performances using iPSYCH consortium data across multiple methods and data integration protocols provides a useful framework in designing workflows to construct next-generation biobanks or conduct biobank-scale a
Externí odkaz:
https://doaj.org/article/da68746f7ed94072a9a90b5153feccaf
Autor:
Veera M. Rajagopal, Andrea Ganna, Jonathan R. I. Coleman, Andrea Allegrini, Georgios Voloudakis, Jakob Grove, Thomas D. Als, Henriette T. Horsdal, Liselotte Petersen, Vivek Appadurai, Andrew Schork, Alfonso Buil, Cynthia M. Bulik, Jonas Bybjerg-Grauholm, Marie Bækvad-Hansen, David M. Hougaard, Ole Mors, Merete Nordentoft, Thomas Werge, iPSYCH-Broad Consortium, Preben Bo Mortensen, Gerome Breen, Panos Roussos, Robert Plomin, Esben Agerbo, Anders D. Børglum, Ditte Demontis
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Cognitive functions of individuals with psychiatric disorders differ from that of the general population. Such cognitive differences often manifest early in life as differential school performance and have a strong genetic basis. Here we mea
Externí odkaz:
https://doaj.org/article/ed05f0cb3a754525a813a4518791dddd
Autor:
Robin J. Hofmeister, Simone Rubinacci, Diogo M. Ribeiro, Alfonso Buil, Zoltán Kutalik, Olivier Delaneau
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Studies on parent-of-origin effects have been limited in terms of sample size due to lack of parental genomes or known genealogies. Here, the authors develop a method to infer the parent-of-origin of an individual alleles in biobank-scale datasets, w
Externí odkaz:
https://doaj.org/article/77090dd6063a448986bd889a487ceecd
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 13, Iss 1, Pp 1-15 (2021)
Abstract Background Language plays a major role in human behavior. For this reason, neurodevelopmental and psychiatric disorders in which linguistic ability is impaired could have a big impact on the individual’s social interaction and general well
Externí odkaz:
https://doaj.org/article/551d3e684f684be0aaa535c21a58d5b9
Autor:
Jiangming Sun, Yunpeng Wang, Lasse Folkersen, Yan Borné, Inge Amlien, Alfonso Buil, Marju Orho-Melander, Anders D. Børglum, David M. Hougaard, Regeneron Genetics Center, Olle Melander, Gunnar Engström, Thomas Werge, Kasper Lage
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
The application of polygenic risk scores to individual-level disease susceptibility is challenging, as risk is evaluated at a group-level. Here, the authors describe a machine learning method, Mondrian Cross-Conformal Prediction, that reports disease
Externí odkaz:
https://doaj.org/article/1f27829d10184dee8d91f723afe0978e
Publikováno v:
JMIR Research Protocols, Vol 11, Iss 11, p e39252 (2022)
BackgroundNecrotizing soft tissue infections (NSTIs) are complex multifactorial diseases characterized by rapid bacterial proliferation and progressive tissue death. Treatment is multidisciplinary, including surgery, broad-spectrum antibiotics, and i
Externí odkaz:
https://doaj.org/article/19748ec6df2a452791ab057ce18ade1e