Výsledky vyhledávání - "Alfons B.A. Kroese"

Chronic alcohol consumption induces an overproduction of NO by nNOS- and iNOS-expressing myenteric neurons in the murine small intestine

Autor: Éva Fekete, L. Van Nassauw, Dirk Adriaensen, Jean-Pierre Timmermans, Monika Krecsmarik, P. Torfs, Mária Bagyánszki, Alfons B.A. Kroese

Publikováno v: Neurogastroenterology & Motility. 23:e237-e248

Background There are indications that alterations in the nitric oxide (NO) system of relaxation mediate gastrointestinal motor disturbances induced by chronic alcohol consumption (CAC). As CAC is known to inhibit the motility of the mouse small intes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::138dd4e360816e115fb45d761e543f68
https://doi.org/10.1111/j.1365-2982.2011.01707.x

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CGRP1 receptor activation induces piecemeal release of protease-1 from mouse bone marrow-derived mucosal mast cells

Autor: Remco H.S. Westerink, L. Van Nassauw, Alfons B.A. Kroese, Jean-Pierre Timmermans, Louis M. A. Akkermans, Jakub Rychter

Publikováno v: Neurogastroenterology & Motility. 23:e57-e68

Background The parasitized or inflamed gastrointestinal mucosa shows an increase in the number of mucosal mast cells (MMC) and the density of extrinsic primary afferent nerve fibers containing the neuropeptide, calcitonin gene-related peptide (CGRP).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b4effc3484cba7e1f208f2d43d207e50
https://doi.org/10.1111/j.1365-2982.2010.01617.x

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Immunoglobulin-free light chains mediate antigen-specific responses of murine dorsal root ganglion neurons

Autor: Frank A. Redegeld, Maurice W. van der Heijden, Frans P. Nijkamp, Alfons B.A. Kroese, Anneke Rijnierse, Jean-Pierre Timmermans, Aletta D. Kraneveld, Bart R. Blokhuis, Andries S. Koster

Publikováno v: Journal of neuroimmunology

Immunoglobulin-free light chains (IgLC) secreted by B lymphocytes, have been shown to mediate hypersensitivity by inducing antigen-specific mast cell activation. Although both mast cells and sensory neurons contribute to the hypersensitivity response

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ac53a997eca8500d585257140d80083
https://doi.org/10.1016/j.jneuroim.2009.01.008

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Pretreatment but not treatment with probiotics abolishes mouse intestinal barrier dysfunction in acute pancreatitis

Autor: Hein G. Gooszen, Marguerite E.I. Schipper, Harro M. Timmerman, Alfons B.A. Kroese, Louis M. A. Akkermans, L. Paul van Minnen, Jakub Rychter, Ger T. Rijkers, Andre Verheem

Publikováno v: Surgery, 145, 157-67
Surgery, 145, 2, pp. 157-67

Background Intestinal barrier failure during acute pancreatitis (AP) is associated with translocation of luminal bacteria, resulting in infectious complications. We examined the effects of multispecies probiotics on the intestinal barrier impairment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f290ec88a51ca365abd246101b0ae9
https://doi.org/10.1016/j.surg.2008.09.011

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Functional live cell imaging of the pulmonary neuroepithelial body microenvironment

Autor: Daniela Riccardi, Dirk Adriaensen, Jean-Pierre Timmermans, Isabel Pintelon, Ian De Proost, Paul J. Kemp, Inge Brouns, Alfons B.A. Kroese

Publikováno v: American Journal of Respiratory Cell and Molecular Biology, 39(2), 180-189. AMER THORACIC SOC
American journal of respiratory cell and molecular biology

Pulmonary neuroepithelial bodies (NEBs) are densely innervated groups of neuroendocrine cells invariably accompanied by Clara-like cells. Together with NEBs, Clara-like cells form the so-called "NEB microenvironment," which recently has been assigned

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::273e6ef92cda5acbe2b61263eb31f5a9
https://research.rug.nl/en/publications/9d8a45aa-e374-4d0f-a91f-85f333f10207

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Indomethacin disrupts the protective effect of phosphatidylcholine against bile salt-induced ileal mucosa injury

Autor: N. G. Venneman, Lma Akkermans, Alfons B.A. Kroese, J. E. Van Dijk, M. Petruzzelli, A. Verheem, K. J. van Erpecum

Publikováno v: European Journal of Clinical Investigation. 36:105-112

Background Indomethacin (Indo) exerts local toxic effects on small intestinal mucosa, possibly in association with hydrophobic bile salts. We investigated the potential toxic effects of Indo on ileal mucosa and the role of phosphatidylcholine (PC). M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb1b4dde16b09b1e4c5fa1277641e48d
https://doi.org/10.1111/j.1365-2362.2006.01595.x

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Ion channel regulation of the dynamical instability of the resting membrane potential in saccular hair cells of the green frog (Rana esculenta)

Autor: Finn Jørgensen, Alfons B.A. Kroese

Publikováno v: Acta Physiologica Scandinavica. 185:271-290

Aims: We investigated the ion channel regulation of the resting membrane potential of hair cells with the aim to determine if the resting membrane potential is poised close to instability and thereby a potential cause of the spontaneous afferent spik

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::88f49c070ce9501730e52aa406f48d61
https://doi.org/10.1111/j.1365-201x.2005.01495.x

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In vitro activation of murine DRG neurons by CGRP-mediated mucosal mast cell degranulation

Autor: L. Van Nassauw, Alfons B.A. Kroese, Hugh R. P. Miller, A. De Laet, Jean-Pierre Timmermans, Jeremy K. Brown, P.P. Van Bogaert, F De Jonge

Publikováno v: American journal of physiology: gastrointestinal and liver physiology
American Journal of Physiology-Gastrointestinal and Liver Physiology, 287(1), G178-G191. AMER PHYSIOLOGICAL SOC

Upregulation of CGRP-immunoreactive (IR) primary afferent nerve fibers accompanied by mastocytosis is characteristic for the Schistosoma mansoni-infected murine ileum. These mucosal mast cells (MMC) and CGRP-IR fibers, which originate from dorsal roo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c246ba7d21fac5b9251370c05c1c2bc5
https://research.rug.nl/en/publications/26c287e8-02b3-4d45-844e-440651eb97f3

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Interleukin-1β activates specific populations of enteric neurons and enteric glia in the guinea pig ileum and colon

Autor: Alfons B.A. Kroese, Joelle M. Bradley, Catherine M. Keenan, Keith A. Sharkey, Eric T. T. L. Tjwa

Publikováno v: American Journal of Physiology-Gastrointestinal and Liver Physiology, 285(6), G1268-G1276. AMER PHYSIOLOGICAL SOC

Fos expression was used to assess whether the proinflammatory cytokine interleukin-1beta (IL-1beta) activated specific, chemically coded neuronal populations in isolated preparations of guinea pig ileum and colon. Whether the effects of IL-1beta were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e29edebe69c12719c69f3d78fea8a933
https://doi.org/10.1152/ajpgi.00073.2003

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Myenteric nitrergic neurons along the rat esophagus: evidence for regional and strain differences in age-related changes

Autor: Luc Van Nassauw, Alfons B.A. Kroese, Dirk Adriaensen, Jean-Pierre Timmermans, Mei Wu

Publikováno v: Histochemistry and cell biology

Several studies have suggested an age-related reduction in the number of myenteric neurons in the lower gastrointestinal (GI) tract linked to changes in GI neuromuscular functions. The present study, combining protein gene product 9.5 immunostaining

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7821a843a1659374c4ef25d51583b2de
https://doi.org/10.1007/s00418-003-0526-3

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