Zobrazeno 1 - 10
of 681
pro vyhledávání: '"Alfio, Quarteroni"'
Autor:
Alberto Zingaro, Zan Ahmad, Eugene Kholmovski, Kensuke Sakata, Luca Dede’, Alan K. Morris, Alfio Quarteroni, Natalia A. Trayanova
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Stroke, a major global health concern often rooted in cardiac dynamics, demands precise risk evaluation for targeted intervention. Current risk models, like the $$\text {CHA}_2\text {DS}_2\text {-VASc}$$ CHA 2 DS 2 -VASc score, often lack th
Externí odkaz:
https://doaj.org/article/be9410f818cb497cbf2f6c5cc32d59d7
Autor:
Andrea Tonini, Christian Vergara, Francesco Regazzoni, Luca Dede’, Roberto Scrofani, Chiara Cogliati, Alfio Quarteroni
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Impaired cardiac function has been described as a frequent complication of COVID-19-related pneumonia. To investigate possible underlying mechanisms, we represented the cardiovascular system by means of a lumped-parameter 0D mathematical mod
Externí odkaz:
https://doaj.org/article/c2744f835b7c4d3fb41839fa9955b3ac
Autor:
Matteo Salvador, Marina Strocchi, Francesco Regazzoni, Christoph M. Augustin, Luca Dede’, Steven A. Niederer, Alfio Quarteroni
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-8 (2024)
Abstract Cardiac digital twins provide a physics and physiology informed framework to deliver personalized medicine. However, high-fidelity multi-scale cardiac models remain a barrier to adoption due to their extensive computational costs. Artificial
Externí odkaz:
https://doaj.org/article/4cfd49fd596e46d6a53d951ad7469981
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Predicting the evolution of systems with spatio-temporal dynamics in response to external stimuli is essential for scientific progress. Traditional equations-based approaches leverage first principles through the numerical approximation of d
Externí odkaz:
https://doaj.org/article/aa3772de0c44430999b6e551a1853e49
Autor:
Pasquale Claudio Africa, Roberto Piersanti, Francesco Regazzoni, Michele Bucelli, Matteo Salvador, Marco Fedele, Stefano Pagani, Luca Dede’, Alfio Quarteroni
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-38 (2023)
Abstract Background Simulating the cardiac function requires the numerical solution of multi-physics and multi-scale mathematical models. This underscores the need for streamlined, accurate, and high-performance computational tools. Despite the dedic
Externí odkaz:
https://doaj.org/article/33983167914b4bbda2741134ad508165
Publikováno v:
Infectious Disease Modelling, Vol 8, Iss 3, Pp 672-703 (2023)
In the context of SARS-CoV-2 pandemic, mathematical modelling has played a fundamental role for making forecasts, simulating scenarios and evaluating the impact of preventive political, social and pharmaceutical measures. Optimal control theory repre
Externí odkaz:
https://doaj.org/article/afb4e4b5ead74f29a0e48c27b5a13f47
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract The aim of this paper is to introduce a new mathematical model that simulates myocardial blood perfusion that accounts for multiscale and multiphysics features. Our model incorporates cardiac electrophysiology, active and passive mechanics,
Externí odkaz:
https://doaj.org/article/256c1a59dcda4e7486b0f5a1e32a9c2e
Publikováno v:
Mathematics in Engineering, Vol 5, Iss 2, Pp 1-38 (2023)
The numerical simulation of several virtual scenarios arising in cardiac mechanics poses a computational challenge that can be alleviated if traditional full-order models (FOMs) are replaced by reduced order models (ROMs). For example, in the case of
Externí odkaz:
https://doaj.org/article/d7f2004d8812419c9a7c2b016868d8da
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-32 (2023)
Abstract Background Modeling the whole cardiac function involves the solution of several complex multi-physics and multi-scale models that are highly computationally demanding, which call for simpler yet accurate, high-performance computational tools
Externí odkaz:
https://doaj.org/article/0f56f24644bf4ec5808742de38616724
Publikováno v:
Mathematics in Engineering, Vol 5, Iss 1, Pp 1-23 (2023)
We face a rigidity problem for the fractional $ p $-Laplace operator to extend to this new framework some tools useful for the linear case. It is known that $ (-\Delta)^s(1-|x|^{2})^s_+ $ and $ -\Delta_p(1-|x|^{\frac{p}{p-1}}) $ are constant function
Externí odkaz:
https://doaj.org/article/d76370a300244676bd26fbfd3f6bfd35