Statistical analysis plan for the replacing protein via enteral nutrition in a stepwise approach in critically ill patients (REPLENISH) randomized clinical trial.

Autor: Arabi YM; Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, King Abdullah International Medical Research Center, ICU, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia. arabi@ngha.med.sa., Al-Dorzi HM; Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, King Abdullah International Medical Research Center, ICU, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia., Aldibaasi O; King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia., Sadat M; Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, King Abdullah International Medical Research Center, ICU, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia., Jose J; King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia., Muharib D; Intensive Care Department, King Saud Medical City, Riyadh, Saudi Arabia., Algethamy H; Department of Anesthesia and Critical Care, King Abdulaziz University, King Abdulaziz University Hospital, Jeddah, Saudi Arabia., Al-Fares AA; Department of Anesthesia, Critical Care Medicine and Pain Medicine, Al-Amiri Hospital, Ministry of Health, Kuwait City, Kuwait., Al-Hameed F; Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia., Mady A; Intensive Care Department, King Saud Medical City, Riyadh, Saudi Arabia.; Department of Anesthesiology and Surgical Intensive Care, Tanta University Hospitals, Tanta, Egypt., Kharaba A; Pulmonary & Critical Care Departments, King Fahad Hospital, Critical Care Units- Madinah Region, Ministry of Health, Madinah, Saudi Arabia., Al Bshabshe A; Department of Critical Care Medicine, Aseer Central Hospital, King Khalid University, Abha, Saudi Arabia., Maghrabi K; Internal Medicine, Critical Care, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia., AlGhamdi K; Internal Medicine, Critical Care, King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia., Rasool G; Department of Anesthesiology and Surgical Intensive Care, Tanta University Hospitals, Tanta, Egypt., AlGhamdi A; Department of Intensive Care Services, Prince Sultan Military Medical City, Riyadh, Saudi Arabia., Almekhlafi GA; Department of Intensive Care Services, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.; Intensive Care Department, King Salman Bin Abdulaziz Medical City, Madinah, Saudi Arabia., Chalabi J; Intensive Care Department, King Abdulaziz Medical City, King Abdullah International Medical Research Center, AlAhsa Ministry of National Guard Health Affairs, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia., AlHumedi HI; Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, King Abdullah International Medical Research Center, ICU, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia., Sakkijha MH; Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, King Abdullah International Medical Research Center, ICU, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia., Alamrey NK; Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, King Abdullah International Medical Research Center, ICU, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia., Alaskar AS; Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, King Abdullah International Medical Research Center, ICU, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia., Alhutail RH; Department of Intensive Care Services, Prince Sultan Military Medical City, Riyadh, Saudi Arabia., Sifaoui K; Pulmonary & Critical Care Departments, King Fahad Hospital, Critical Care Units- Madinah Region, Ministry of Health, Madinah, Saudi Arabia., Alqahtani R; Department of Critical Care, College of Medicine, King Saud University, Riyadh, Saudi Arabia., Qureshi AS; Intensive Care Department, Prince Mohammed Bin Abdulaziz Hospital, Ministry of National Guard Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Madinah, Saudi Arabia., Hejazi MM; Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, King Abdullah International Medical Research Center, ICU, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia., Arishi H; Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, King Abdullah International Medical Research Center, ICU, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia., AlQahtani S; Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, King Abdullah International Medical Research Center, ICU, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia., Ghazi AM; Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, King Abdullah International Medical Research Center, ICU, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia., Baaziz ST; Department of Anesthesia and Critical Care, King Abdulaziz University, King Abdulaziz University Hospital, Jeddah, Saudi Arabia., Azhar AO; Department of Anesthesia and Critical Care, King Abdulaziz University, King Abdulaziz University Hospital, Jeddah, Saudi Arabia., Alabbas SF; Department of Anesthesia and Critical Care, King Abdulaziz University, King Abdulaziz University Hospital, Jeddah, Saudi Arabia., AlAqeely M; Intensive Care Department, King Saud Medical City, Riyadh, Saudi Arabia., AlOrabi O; Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia., Al-Mutawa A; Department of Anesthesia, Critical Care Medicine and Pain Medicine, Al-Amiri Hospital, Ministry of Health, Kuwait City, Kuwait., AlOtaibi M; Intensive Care Department, King Saud Medical City, Riyadh, Saudi Arabia., Elghannam MF; Internal Medicine, Critical Care, King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia., Almaani M; Adult Critical Care Services, King Fahad Medical City, Riyadh, Saudi Arabia., Buabbas SF; Department of Anesthesia, Critical Care and Pain Medicine, Jaber Al-Ahmed Al-Sabah Hospital, Kuwait City, Kuwait., Alfilfil WAM; Department of Intensive Care, Prince Mohammed Bin Abdulaziz Hospital, Riyadh, Saudi Arabia., Alshahrani MS; Department of Emergency and Critical Care, King Fahad Hospital of the University, Imam Abdulrahman Bin Faisal University, Al Khobar, Saudi Arabia., Starkopf J; Clinic of Anaesthesiology and Intensive Care, University of Tartu, Tartu University Hospital, Tartu, Estonia., Preiser JC; Department of Intensive Care, Erasme University Hospital, Brussels, Belgium., Perner A; Department of Intensive Care, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., AlMubarak JH; Department of Anesthesia, Critical Care and Pain Medicine, Jaber Al-Ahmed Al-Sabah Hospital, Kuwait City, Kuwait., Hazem WM; Department of Intensive Care, Prince Mohammed Bin Abdulaziz Hospital, Riyadh, Saudi Arabia., Albrahim T; Department of Emergency and Critical Care, King Fahad Hospital of the University, Imam Abdulrahman Bin Faisal University, Al Khobar, Saudi Arabia., Al-Dawood A; Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, King Abdullah International Medical Research Center, ICU, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.

Publikováno v: Trials [Trials] 2024 May 02; Vol. 25 (1), pp. 296. Date of Electronic Publication: 2024 May 02.