Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Alfeu Zanotto-Filho"'
Autor:
Jonathan Paulo Agnes, Barbara dos Santos, Raquel Nascimento das Neves, Vitória Maria Marques Luciano, Larissa Benvenutti, Fernanda Capitanio Goldoni, Roberta Giusti Schran, José Roberto Santin, Nara Lins Meira Quintão, Alfeu Zanotto-Filho
Publikováno v:
Antioxidants, Vol 12, Iss 10, p 1893 (2023)
Peripheral neuropathy is an important adverse effect caused by some chemotherapeutic agents, including oxaliplatin (OXA). OXA-induced peripheral neuropathy (OIPN) is a challenging condition due to diagnostic complexities and a lack of effective treat
Externí odkaz:
https://doaj.org/article/dc3331dffa784fa0b46dabd9c88948bd
Autor:
Daniel de Oliveira Patricio, Greicy Brisa Malaquias Dias, Lucilene Wildner Granella, Ben Trigg, Helena Claire Teague, Dina Bittencourt, André Báfica, Alfeu Zanotto-Filho, Brian Ferguson, Daniel Santos Mansur
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Zika virus (ZIKV) is a single-strand RNA mosquito-borne flavivirus with significant public health impact. ZIKV infection induces double-strand DNA breaks (DSBs) in human neural progenitor cells that may contribute to severe neuronal manifestations in
Externí odkaz:
https://doaj.org/article/640bbd157b8d40018abad90c6de32dfa
Autor:
Nauana Somensi, Pedro Ozorio Brum, Vitor de Miranda Ramos, Juciano Gasparotto, Alfeu Zanotto-Filho, Diana Carolina Rostirolla, Maurilio da Silva Morrone, José Claudio Fonseca Moreira, Daniel Pens Gelain
Publikováno v:
Cellular Physiology and Biochemistry, Vol 42, Iss 6, Pp 2507-2522 (2017)
Background/Aims: Heat shock protein 70 (HSP70) has been recently described with extracellular actions, where it is actively released in inflammatory conditions. Acting as DAMPs (damage associated molecular pattern), extracellular HSP70 (eHSP70) inter
Externí odkaz:
https://doaj.org/article/946e983d6840408e9d617c9b52a43cdb
Autor:
Alfeu Zanotto-Filho, Ravi Dashnamoorthy, Eva Loranc, Luis H T de Souza, José C F Moreira, Uthra Suresh, Yidong Chen, Alexander J R Bishop
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153970 (2016)
Alkylating agents are a key component of cancer chemotherapy. Several cellular mechanisms are known to be important for its survival, particularly DNA repair and xenobiotic detoxification, yet genomic screens indicate that additional cellular compone
Externí odkaz:
https://doaj.org/article/d16fd51e837e4abd85054b4467bb3b5f
Autor:
Alexander J.R. Bishop, Yidong Chen, José C.F. Moreira, Rosângela Mayer Gonçalves, Xavier Bernard, Aparna Gorthi, Sonal S. Tonapi, Eva Loranc, V. Pragathi Masamsetti, Alfeu Zanotto-Filho
Descriptive panel of hot-spot mutations in NFE2L2 and KEAP1 genes across lung and head and neck carcinoma samples available in the TCGA database (Provisional datasets) as obtained from the "Mutations" tool available in the TCGA cBioportal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::136aabe2c760bfae4a4789aa38c4e1b7
https://doi.org/10.1158/1535-7163.22508418.v1
https://doi.org/10.1158/1535-7163.22508418.v1
Autor:
Alexander J.R. Bishop, Yidong Chen, José C.F. Moreira, Rosângela Mayer Gonçalves, Xavier Bernard, Aparna Gorthi, Sonal S. Tonapi, Eva Loranc, V. Pragathi Masamsetti, Alfeu Zanotto-Filho
Supplementary figure legends for figures S1 to S5.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdae1ffdfa8269c7fd669ece0fe5a483
https://doi.org/10.1158/1535-7163.22508415
https://doi.org/10.1158/1535-7163.22508415
Publikováno v:
Cancer Research. 82:P5-10
TP53 is the most frequently mutated gene in most types of human cancer, including breast cancer. The triple-negative breast cancer (TNBC) subtype in particular displays TP53 mutation in approximately 80% of patients. Unlike other breast cancer subtyp
Autor:
Daniel de Oliveira, Patricio, Greicy Brisa Malaquias, Dias, Lucilene Wildner, Granella, Ben, Trigg, Helena Claire, Teague, Dina, Bittencourt, André, Báfica, Alfeu, Zanotto-Filho, Brian, Ferguson, Daniel Santos, Mansur
Publikováno v:
Frontiers in immunology. 13
Autor:
Ingrid A. V. Wolin, Ana Paula M. Nascimento, Rodrigo Seeger, Gabriela G. Poluceno, Alfeu Zanotto-Filho, Claudia B. Nedel, Carla I. Tasca, Sarah Elizabeth Gomes Correia, Messias Vital Oliveira, Vanir Reis Pinto-Junior, Vinicius Jose Silva Osterne, Kyria Santiago Nascimento, Benildo Sousa Cavada, Rodrigo Bainy Leal
Publikováno v:
Glycoconjugate journal.
Glioblastoma multiforme (GBM) is the most aggressive type of glioma, displaying atypical glycosylation pattern that may modulate signaling pathways involved in tumorigenesis. Lectins are glycan binding proteins with antitumor properties. The present
Autor:
Marcelo Falchetti, Marina Delgobo, Helena Zancanaro, Karoline Almeida, Raquel Nascimento das Neves, Barbara dos Santos, Natália Marcéli Stefanes, Alexander Bishop, Maria Cláudia Santos-Silva, Alfeu Zanotto-Filho
Publikováno v:
Computers in Biology and Medicine. 152:106347
Auranofin is a thioredoxin reductase-1 inhibitor originally approved for the treatment of rheumatoid arthritis. Recently, auranofin has been repurposed as an anticancer drug, with pharmacological activity reported in multiple cancer types. In this st