Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Alexus D, Kolb"'
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-30 (2019)
Abstract Introduction In a cancer-free environment in the adult, the skeleton continuously undergoes remodeling. Bone-resorbing osteoclasts excavate erosion cavities, and bone-depositing osteoblasts synthesize osteoid matrix that forms new bone, with
Externí odkaz:
https://doaj.org/article/bd65e56acfd14d24beac4740baf0a992
Publikováno v:
Cancers, Vol 13, Iss 2, p 263 (2021)
Breast cancer (BC) metastases to bone disrupt the balance between osteoblasts and osteoclasts, leading to excessive bone resorption. We identified a novel subpopulation of osteoblasts with tumor-inhibitory properties, called educated osteoblasts (EOs
Externí odkaz:
https://doaj.org/article/6c4cc6b263df40ca96f175f6960da514
Publikováno v:
Cancers, Vol 13, Iss 3, p 507 (2021)
Breast cancer commonly metastasizes to bone, resulting in osteolytic lesions and poor patient quality of life. The bone extracellular matrix (ECM) plays a critical role in cancer cell metastasis by means of the physical and biochemical cues it provid
Externí odkaz:
https://doaj.org/article/54f87a4cfed5409e9a2eaee46eddd414
Autor:
Alexus D. Kolb, Karen M. Bussard
Publikováno v:
Cancers, Vol 11, Iss 7, p 1020 (2019)
Bone is a preferential site for cancer metastases, including multiple myeloma, prostate, and breast cancers.The composition of bone, especially the extracellular matrix (ECM), make it an attractive site for cancer cell colonization and survival. The
Externí odkaz:
https://doaj.org/article/6041bac435a14a6daa88fa2a853e8964
Publikováno v:
Cancers, Vol 10, Iss 6, p 182 (2018)
The skeleton is a unique structure capable of providing support for the body. Bone resorption and deposition are controlled in a tightly regulated balance between osteoblasts and osteoclasts with no net bone gain or loss. However, under conditions of
Externí odkaz:
https://doaj.org/article/30d68342eba34c4e8b29958ef0edba32
Publikováno v:
Cancers
Volume 13
Issue 2
Cancers, Vol 13, Iss 263, p 263 (2021)
Volume 13
Issue 2
Cancers, Vol 13, Iss 263, p 263 (2021)
Breast cancer (BC) metastases to bone disrupt the balance between osteoblasts and osteoclasts, leading to excessive bone resorption. We identified a novel subpopulation of osteoblasts with tumor-inhibitory properties, called educated osteoblasts (EOs
Publikováno v:
Advances in experimental medicine and biology. 1225
Many cancers commonly metastasize to bone. After entering the bone, cancer cells can interact with surrounding stromal cells, which ultimately influences metastasis progression. Extracellular vesicles, direct cell contact and gap junctions, and cytok
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030357269
Many cancers commonly metastasize to bone. After entering the bone, cancer cells can interact with surrounding stromal cells, which ultimately influences metastasis progression. Extracellular vesicles, direct cell contact and gap junctions, and cytok
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c017af572a4eb3f22ac181a2e42651ba
https://doi.org/10.1007/978-3-030-35727-6_1
https://doi.org/10.1007/978-3-030-35727-6_1
Publikováno v:
Cancer Research. 79:GS1-03
BrCa preferentially metastasizes to bone, where the 5-year relative survival rate is In a cancer-free environment in the adult, the skeleton continuously undergoes remodeling. Osteoclasts excavate erosion cavities and osteoblasts (OB) synthesize bone
Autor:
Karen M. Bussard, Alexus D. Kolb
Publikováno v:
Cancers, Vol 11, Iss 7, p 1020 (2019)
Cancers
Cancers
Bone is a preferential site for cancer metastases, including multiple myeloma, prostate, and breast cancers.The composition of bone, especially the extracellular matrix (ECM), make it an attractive site for cancer cell colonization and survival. The