Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Alexis Voulgaropoulos"'
Publikováno v:
BMC Biotechnology, Vol 21, Iss 1, Pp 1-16 (2021)
Abstract Background Human cerebral organoids (hCO) are attractive systems due to their ability to model important brain regions and transcriptomics of early in vivo brain development. To date, they have been used to understand the effects of genetics
Externí odkaz:
https://doaj.org/article/94a1b449c5894e8195d07c3036bbd70e
Human Cerebral Organoids Reveal Early Spatiotemporal Dynamics and Pharmacological Responses of UBE3A
Publikováno v:
Stem Cell Reports
Summary Angelman syndrome is a complex neurodevelopmental disorder characterized by delayed development, intellectual disability, speech impairment, and ataxia. It results from the loss of UBE3A protein, an E3 ubiquitin ligase, in neurons of the brai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82d561bb1b87df41dc68bfd4bd8839c8
http://europepmc.org/articles/PMC7561513
http://europepmc.org/articles/PMC7561513
Autor:
Alexis Voulgaropoulos
Publikováno v:
Environmental Progress & Sustainable Energy. 41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89703c8abc937db5026c2a6398ec0a21
https://doi.org/10.1002/ep.13800
https://doi.org/10.1002/ep.13800
Publikováno v:
BMC Biotechnology
BMC Biotechnology, Vol 21, Iss 1, Pp 1-16 (2021)
BMC Biotechnology, Vol 21, Iss 1, Pp 1-16 (2021)
Background Human cerebral organoids (hCO) are attractive systems due to their ability to model important brain regions and transcriptomics of early in vivo brain development. To date, they have been used to understand the effects of genetics and solu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a355585941a5f5242fe9b752d3976f92
https://doi.org/10.1186/s12896-021-00718-2
https://doi.org/10.1186/s12896-021-00718-2
SUMMARYHuman neurodevelopment and its associated diseases are complex and challenging to study. This has driven recent excitement for human cerebral organoids (hCOs) as research and screening tools. These models are steadily proving their utility; ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::785cbc2d241f8e503d66b20a72b7cadb
https://doi.org/10.1101/742213
https://doi.org/10.1101/742213
