Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Alexis Styche"'
Autor:
Maria Grupillo, Robert Lakomy, Xuehui Geng, Alexis Styche, William A Rudert, Massimo Trucco, Yong Fan
Publikováno v:
BioTechniques, Vol 51, Iss 6, Pp 417-420 (2011)
Intracellular staining is a widely used flow cytometry (FCM)-based technique to detect the expression of cytoslio nucleic antigens. However, intracellular staining of cells expressing cytosolic fluorescent protein (FP) markers was proven to be proble
Externí odkaz:
https://doaj.org/article/608effbdb10a4b65b9ebdb32146ecf47
Autor:
Angela M. Alexander, Christopher Pecoraro, Alexis Styche, William A. Rudert, Panayiotis V. Benos, Steven Ringquist, Massimo Trucco
Publikováno v:
BioTechniques, Vol 38, Iss 1, Pp 87-94 (2005)
SOP3 is a web-based software tool for designing oligonucleotide primers for use in the analysis of single nucleotide polymorphisms (SNPs). Accessible via the Internet, the application is optimized for developing the PCR and sequencing primers that ar
Externí odkaz:
https://doaj.org/article/bfb7659b8b7f4307b28870a70e967761
Autor:
Tatiana D. Zorina, Massimo Trucco, Robert J. Lakomy, Suzanne Bertera, Janet L. Markman, Vladimir M. Subbotin, Alexis Styche, Benjamin K. Nti
Publikováno v:
Cellular & Molecular Immunology. 9:455-463
Previously, we established a model in which physiologically adequate function of the autologous β cells was recovered in non-obese diabetic (NOD) mice after the onset of hyperglycemia by rendering them hemopoietic chimera. These mice were termed ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e28f388fc03adc0d8adee7bfc069b29
https://doi.org/10.1038/cmi.2012.36
https://doi.org/10.1038/cmi.2012.36
Autor:
Massimo Trucco, Creg J. Workman, Alexis Styche, Jon D. Piganelli, Meghan M. Delmastro, Dario A. A. Vignali
Publikováno v:
Diabetes
Preventing activation of diabetogenic T cells is critical for delaying type 1 diabetes onset. The inhibitory molecule lymphocyte activation gene 3 (LAG-3) and metalloprotease tumor necrosis factor-α converting enzyme (TACE) work together to regulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb57a73bca9be43c4a91b64520ecbed2
https://doi.org/10.2337/db11-1591
https://doi.org/10.2337/db11-1591
Autor:
Xuehui Geng, Yong Fan, Maria Grupillo, Robert Lakomy, Alexis Styche, William A. Rudert, Massimo Trucco
Publikováno v:
BioTechniques. 51:417-420
Intracellular staining is a widely used flow cytometry (FCM)-based technique to detect the expression of cytoslio nucleic antigens. However, intracellular staining of cells expressing cytosolic fluorescent protein (FP) markers was proven to be proble
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4603b7648a651f3891af881d14009914
https://doi.org/10.2144/000113780
https://doi.org/10.2144/000113780
Publikováno v:
Diabetologia. 54:2702-2712
Reactive oxygen species (ROS) generated during hyperglycaemia are implicated in the development of diabetic vascular complications. High glucose increases oxidative stress in endothelial cells and induces apoptosis. A major source of ROS in endotheli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06412ba2198ce0d2a98ce1057d60f2e3
https://doi.org/10.1007/s00125-011-2251-0
https://doi.org/10.1007/s00125-011-2251-0
Autor:
Janet Knox, Jo Harnaha, Debra Lafreniere, Kenneth Hogeland, Karen Nylander, Brett E. Phillips, Massimo Trucco, Michael Gallo, Jennifer Machen, Nick Giannoukakis, Robert Lakomy, Alexis Styche, Kimberly A. Gillis, Larry Brown
Publikováno v:
Diabetes. 57:1544-1555
OBJECTIVE—This study was aimed at ascertaining the efficacy of antisense oligonucleotide-formulated microspheres to prevent type 1 diabetes and to reverse new-onset disease.RESEARCH DESIGN AND METHODS—Microspheres carrying antisense oligonucleoti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1059a0441eb0a4a08cb6c6e1660ae581
https://doi.org/10.2337/db07-0507
https://doi.org/10.2337/db07-0507
Autor:
Lorenzo Pasquali, Giuliana Trucco, Rohit Bhargava, Alexis Styche, Steven Ringquist, Ahmed Bedeir
Publikováno v:
Cancer Letters. 257:136-144
Epigenetic silencing of specific genes is associated with cancer progression. CpG islands are present at higher frequency in promoter regions, their methylation leading to gene underexpression. Pyrosequencing provides sequencing analysis of genetic m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::145c7d48455acd5dc28f0f0cc17d0f68
https://doi.org/10.1016/j.canlet.2007.07.010
https://doi.org/10.1016/j.canlet.2007.07.010
Autor:
Alexis Styche, Tatiana D. Zorina
Publikováno v:
Infection and Cancer: Bi-Directorial Interactions ISBN: 9783319206684
The predisposition of cancer patients to infectious diseases which contribute to the gravity of their prognosis is well documented. The current success in therapy of both malignancies and infections is unprecedented. However, the overall co-morbidity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::648209ad9e28021b086c366cbb1a6ea1
https://doi.org/10.1007/978-3-319-20669-1_14
https://doi.org/10.1007/978-3-319-20669-1_14
Autor:
William A. Rudert, Christopher Pecoraro, Crystal M. S. Gilchrist, Steven Ringquist, Alexis Styche, Massimo Trucco, Panagiotis V. Benos
Publikováno v:
Nucleic Acids Research
SOP3v2 is a database-driven graphical web-based application for facilitating genotyping assay design. SOP3v2 accepts data input in numerous forms, including gene names, reference sequence numbers and physical location. For each entry, the application
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae564abbbd77dd8440aca44732d346de
https://doi.org/10.1093/nar/gki483
https://doi.org/10.1093/nar/gki483