Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Alexis S Lopez"'
Autor:
Kiran Mahajan, Domenico Coppola, Sridevi Challa, Bin Fang, Y Ann Chen, Weiwei Zhu, Alexis S Lopez, John Koomen, Robert W Engelman, Charlene Rivera, Rebecca S Muraoka-Cook, Jin Q Cheng, Ernst Schönbrunn, Said M Sebti, H Shelton Earp, Nupam P Mahajan
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9646 (2010)
The AKT/PKB kinase is a key signaling component of one of the most frequently activated pathways in cancer and is a major target of cancer drug development. Most studies have focused on its activation by Receptor Tyrosine Kinase (RTK) mediated Phosph
Externí odkaz:
https://doaj.org/article/7f2b87878a874c4898e87e6d35f2af22
Autor:
Janos L. Tanyi, Leslie M. Randall, Setsuko K. Chambers, Kristina A. Butler, Ira S. Winer, Carrie L. Langstraat, Ernest S. Han, Alexander L. Vahrmeijer, Hye Sook Chon, Mark A. Morgan, Matthew A. Powell, Jill H. Tseng, Alexis S. Lopez, Robert M. Wenham
Publikováno v:
Journal of Clinical Oncology. 41:276-284
PURPOSE The adjunctive use of intraoperative molecular imaging (IMI) is gaining acceptance as a potential means to improve outcomes for surgical resection of targetable tumors. This confirmatory study examined the use of pafolacianine for real-time d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd4fdc6538df0ea93326e8bff0edbb24
https://doi.org/10.1200/jco.22.00291
https://doi.org/10.1200/jco.22.00291
Autor:
David L. Morse, Robert J. Gillies, Stephen R. Grobmyer, Josef Vagner, Bradford W. Carter, Dominique Abrahams, Alexis S. Lopez, Steven A. Enkemann, Mark C. Lloyd, Kellsey Bishop, Marilyn M. Bui, Narges K. Tafreshi
PDF file - 1.5MB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26b34c5b0fcc16566780c8f7dcb7c999
https://doi.org/10.1158/1078-0432.22445811
https://doi.org/10.1158/1078-0432.22445811
Autor:
David L. Morse, Robert J. Gillies, Stephen R. Grobmyer, Josef Vagner, Bradford W. Carter, Dominique Abrahams, Alexis S. Lopez, Steven A. Enkemann, Mark C. Lloyd, Kellsey Bishop, Marilyn M. Bui, Narges K. Tafreshi
Purpose: To develop targeted molecular imaging probes for the noninvasive detection of breast cancer lymph node metastasis.Experimental Design: Six cell surface or secreted markers were identified by expression profiling and from the literature as be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c43ab44166a913f307f9345c6bb7d8f
https://doi.org/10.1158/1078-0432.c.6520566.v1
https://doi.org/10.1158/1078-0432.c.6520566.v1
Autor:
Pawel Swietach, Mark C. Lloyd, Bryce Ordway, Joseph S. Johnson, Marilyn M. Bui, Dominique Abrahams, Y. Kam, Shonagh Russell, E. Ruiz, Liping Xu, Jonathan W. Wojtkowiak, T. Epstein, D. Verduzco, Alexis S. Lopez, Robert J. Gillies
Aggressive cancers commonly ferment glucose to lactic acid at high rates, even in the presence of oxygen. This is known as aerobic glycolysis, or the “Warburg Effect”. It is widely assumed that this is a consequence of the upregulation of glycoly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e2b6d707dfd9ddb11377153287786a1
https://doi.org/10.1101/2021.09.20.461019
https://doi.org/10.1101/2021.09.20.461019
Autor:
Anthony M. Magliocco, Robert M. Wenham, Susan M McCarthy, Sachin M. Apte, Jennifer B. Permuth, Dung-Tsa Chen, Ardeshir Hakam, Johnathan M. Lancaster, Douglas C. Marchion, Daryoush Saeed-Vafa, Alexis S. Lopez, Brett M. Reid
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0256615 (2021)
PLoS ONE
PLoS ONE
Loss of stromal caveolin-1 (Cav-1) is a biomarker of a cancer-associated fibroblast (CAF) phenotype and is related to progression, metastasis, and poor outcomes in several cancers. The objective of this study was to evaluate the clinical significance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ccab72a6d0b4a13c7fdbbfce8e00d8e
https://doaj.org/article/5ca8a7d61e0f4af186e6fa6b2b9a9a6f
https://doaj.org/article/5ca8a7d61e0f4af186e6fa6b2b9a9a6f
Autor:
Shivakumar Vignesh, Valerie E. Stark, Alexis S. Lopez, David L. Morse, Domenico Coppola, Jonathan W. Wojtkowiak, David Shibata, Brian Morse, Binglin Yue, Jongphil Kim, Kamini Sewda, Steven A. Enkemann
Publikováno v:
Oncotarget
Early detection of colorectal cancer (CRC) is crucial for effective treatment. Among CRC screening techniques, optical colonoscopy is widely considered the gold standard. However, it is a costly and invasive procedure with a low rate of compliance. O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6da204683ea805f6c1f107c2546ac2f6
https://doi.org/10.18632/oncotarget.7402
https://doi.org/10.18632/oncotarget.7402
Autor:
Jesus Gonzalez-Bosquet, Christopher L. Cubitt, Nadim Bou Zgheib, Douglas C. Marchion, Yin Xiong, X. Stickles, Robert M. Wenham, Johnathan M. Lancaster, Patricia L. Judson, Anders Berglund, Alexis S. Lopez, Elona Bicaku, Sachin M. Apte, Entidhar Al Sawah
Publikováno v:
Oncology Reports
Elevated serum levels of hepatocyte growth factor (HGF) and high tumor expression of c-Met are both indicators of poor overall survival from ovarian cancer (OVCA). In the present study, we evaluated the role of the HGF signaling pathway in OVCA cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da98e32035e6dcde4afd78da56451daa
https://doi.org/10.3892/or.2013.2329
https://doi.org/10.3892/or.2013.2329
Autor:
Alexis S. Lopez, Tiffany H. Dorsey, Harris G. Yfantis, S.J. Antonia, Bhupendra Rawal, Marylin M. Bui, Jimmy Fulp, Ji-Hyun Lee, Farah Khalil, Hatem Soliman, Dong H. Lee, Stefan Ambs
Publikováno v:
Cancer Immunology, Immunotherapy. 62:829-837
The immunosuppressive enzyme, indoleamine 2,3 dioxygenase (IDO), is overexpressed in many different tumor types including breast cancer. IDO inhibitors synergize with chemotherapy in breast cancer murine models. Characterizing IDO expression in breas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3511880dc677bd72598e61de1c535b5
https://doi.org/10.1007/s00262-013-1393-y
https://doi.org/10.1007/s00262-013-1393-y
Autor:
Haruka Yamaguchi, Takafumi Okabe, Bhupendra Rawal, Jiannong Li, Kiyoko Shibata, Matthew A. Smith, Kazuhiko Nakagawa, Alexis S. Lopez, Kate Fisher, Eric B. Haura, John M. Koomen, Isamu Okamoto, Michiko Kitano, Bin Fang, Yume Morita, Guolin Zhang, Y. Ann Chen, Takeshi Yoshida, Yun Bai
Purpose: Irreversible EGFR-tyrosine kinase inhibitors (TKI) are thought to be one strategy to overcome EGFR-TKI resistance induced by T790M gatekeeper mutations in non–small cell lung cancer (NSCLC), yet they display limited clinical efficacy. We h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::174638d2b062a1a7ad73b2f72c38321c
https://europepmc.org/articles/PMC4119578/
https://europepmc.org/articles/PMC4119578/