Genome-wide association analysis of metabolic syndrome quantitative traits in the GENNID multiethnic family study

Autor: Jia Y. Wan, Deborah L. Goodman, Emileigh L. Willems, Alexis R. Freedland, Trina M. Norden-Krichmar, Stephanie A. Santorico, Karen L. Edwards, American Diabetes GENNID Study Group

Publikováno v: Diabetology & Metabolic Syndrome, Vol 13, Iss 1, Pp 1-15 (2021)

Abstract Background To identify genetic associations of quantitative metabolic syndrome (MetS) traits and characterize heterogeneity across ethnic groups. Methods Data was collected from GENetics of Noninsulin dependent Diabetes Mellitus (GENNID), a

Externí odkaz: https://doaj.org/article/a7efabdc123d4666b16c72541e470efc

Metabolic syndrome is associated with aggressive prostate cancer regardless of race

Autor: Lourdes Guerrios-Rivera, Lauren E. Howard, Emily K. Wiggins, Cathrine Hoyo, Delores J. Grant, Tyler R. Erickson, Jaruda Ithisuphalap, Alexis R. Freedland, Adriana C. Vidal, Jay H. Fowke, Stephen J. Freedland

Publikováno v: Cancer Causes & Control. 34:213-221

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d7f647712e3786241e9abde654a8722a
https://doi.org/10.1007/s10552-022-01649-9

Metabolic syndrome is associated with aggressive prostate cancer regardless of race

Autor: Lourdes, Guerrios-Rivera, Lauren E, Howard, Emily K, Wiggins, Cathrine, Hoyo, Delores J, Grant, Tyler R, Erickson, Jaruda, Ithisuphalap, Alexis R, Freedland, Adriana C, Vidal, Jay H, Fowke, Stephen J, Freedland

Publikováno v: Cancer causescontrol : CCC.

Recent meta-analyses suggest the Metabolic Syndrome (MS) increases high-grade prostate cancer (PC), although studies are inconsistent and few black men were included. We investigated MS and PC diagnosis in black and white men undergoing prostate biop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3ff445c68442a6c8036181701b7add09
https://pubmed.ncbi.nlm.nih.gov/36450931

Asian race and risk of prostate cancer: Results from the REDUCE study

Autor: Ramiro Castro-Santamaria, Adriana C. Vidal, Tom Feng, Emma H. Allott, Daniel Moreira, Stephen J. Freedland, Gerald L. Andriole, Alexis R. Freedland, Taofik Oyekunle

Publikováno v: Vidal, A C, Oyekunle, T, Feng, T, Freedland, A R, Moreira, D, Castro-Santamaria, R, Andriole, G L, Freedland, S J & Allott, E H 2020, ' Asian race and risk of prostate cancer: Results from the REDUCE study ', Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology . https://doi.org/10.1158/1055-9965.EPI-20-0646

Background: Global prostate cancer incidence rates are lower in Asian men than Caucasian men. Whether this is the result of less screening in Asian men remains to be determined. We examined whether Asian race was associated with prostate cancer diagn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9b984fc73ed5e89c52288b8f73692ce
https://pure.qub.ac.uk/en/publications/asian-race-and-risk-of-prostate-cancer-results-from-the-reduce-study(5e87b55e-b59b-431c-9ac4-0088107fd9ff).html

Serum cholesterol levels and tumor growth in a PTEN-null transgenic mouse model of prostate cancer

Autor: Elizabeth M. Masko, Alexis R. Freedland, Keith R. Solomon, George Thomas, Elahe A. Mostaghel, Salvatore V. Pizzo, Emma H. Allott, Everardo Macias, Stephen J. Freedland, Michael R. Freeman, Kristine Pelton

Publikováno v: Prostate cancer and prostatic diseases
Allott, E H, Masko, E M, Freedland, A R, Macias, E, Pelton, K, Solomon, K R, Mostaghel, E A, Thomas, G V, Pizzo, S V, Freeman, M R & Freedland, S J 2018, ' Serum cholesterol levels and tumor growth in a PTEN-null transgenic mouse model of prostate cancer ', Prostate cancer and prostatic diseases, vol. 21, no. 2, pp. 196-203 . https://doi.org/10.1038/s41391-018-0045-x

BACKGROUND: Some, but not all, epidemiologic evidence supports a role for cholesterol, the precursor for steroid hormone synthesis, in prostate cancer. Using a PTEN-null transgenic mouse model of prostate cancer, we tested the effect of modifying ser

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f822836ee0c507f4b8fc5250158baac1
http://europepmc.org/articles/PMC6026483