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pro vyhledávání: '"Alexis Q. Dean"'
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
Antibody-drug conjugates (ADCs) are a rapidly expanding class of biotherapeutics that utilize antibodies to selectively deliver cytotoxic drugs to the tumor site. As of May 2021, the U.S. Food and Drug Administration (FDA) has approved ten ADCs, name
Externí odkaz:
https://doaj.org/article/0ea1fe9accbc4cd4ace5cfd15f8eba42
Autor:
Alexis Q Dean, Charles B Stauft, Julianne D Twomey, Joshua Tan, Luca Varani, Tony T Wang, Baolin Zhang
Publikováno v:
Antibody Therapeutics. 6:49-58
BackgroundNeutralising antibodies against SARS-CoV-2 are a vital component in the fight against COVID-19 pandemic, having the potential of both therapeutic and prophylactic applications. Bispecific antibodies (BsAbs) against SARS-CoV-2 are particular
Publikováno v:
Drug Discovery Today
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enters host cells by interacting with membrane-bound angiotensin-converting enzyme 2 (ACE2), a vital element in the renin-angiotensin system (RAS), which regulates blood pressure,
Publikováno v:
Drug Resistance Updates
The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), represents an unprecedented challenge to global public health. At the time of this review, COVID-19 has been diagnosed in over 40 million cases and associa