Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alexis Poncy"'
Autor:
Pierre-Alexandre Just, Alexis Poncy, Sara Charawi, Rajae Dahmani, Massiré Traore, Typhanie Dumontet, Valérie Drouet, Florent Dumont, Hélène Gilgenkrantz, Sabine Colnot, Benoit Terris, Cédric Coulouarn, Frédéric Lemaigre, Christine Perret
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145400 (2015)
LKB1 is an evolutionary conserved kinase implicated in a wide range of cellular functions including inhibition of cell proliferation, regulation of cell polarity and metabolism. When Lkb1 is inactivated in the liver, glucose homeostasis is perturbed,
Externí odkaz:
https://doaj.org/article/412c98799492461e88d629a8b8f7f103
Autor:
Aline Antoniou, Patrick Jacquemin, Christophe E. Pierreux, Frédéric P. Lemaigre, Sabine Cordi, Alexis Poncy
Publikováno v:
Developmental Biology. 404(2):136-148
In developing liver, cholangiocytes derive from the hepatoblasts and organize to form the bile ducts. Earlier work has shown that the SRY-related High Mobility Group box transcription factor 9 (SOX9) is transiently required for bile duct development,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::611cc8f1bbd65e134764c302b3cb3fb2
Autor:
Céline Demarez, David A. Rosa, Alexis Poncy, Isabelle Manfroid, Younes Achouri, Nicolas Dauguet, Claude Gérard, Patrick T. Gunning, Frédéric P. Lemaigre, Sabine Cordi
Publikováno v:
Hepatology, Vol. 67, p. 313-327 (2018)
Transcriptional networks control the differentiation of the hepatocyte and cholangiocyte lineages from embryonic liver progenitor cells, and their subsequent maturation to the adult phenotype. However, how accurate levels of hepatocyte and cholangioc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69f5cb8584085dec915d6903992328d1
https://pubmed.ncbi.nlm.nih.gov/28833283
https://pubmed.ncbi.nlm.nih.gov/28833283
Autor:
Víola B. Weeda, Daniel C. Aronson, Theodorus B. M. Hakvoort, Frédéric P. Lemaigre, W. T. Labruyere, Farah A. Falix, Alexis Poncy, Dirk R. de Waart, Wouter H. Lamers, Ingrid C. Gaemers
Publikováno v:
Developmental biology, 396(2), 201-213. Academic Press Inc.
Notch signaling plays an acknowledged role in bile-duct development, but its involvement in cholangiocyte-fate determination remains incompletely understood. We investigated the effects of early Notch2 deletion in Notch2fl/fl/Alfp-Cretg/− (“Notch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90b49f22ce7e769629df8419bc48ea51