Zobrazeno 1 - 3
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pro vyhledávání: '"Alexis P Rideau"'
Autor:
Tom P. Monie, Peter Simpson, Christopher W.J. Smith, Stephen Curry, Mike Lorenz, Robert H. Singer, Stefan Hüttelmaier, Stephen Matthews, Alexis P Rideau, Clare Gooding
Publikováno v:
Nature structuralmolecular biology. 13(9)
Polypyrimidine tract-binding protein (PTB) is a regulatory splicing repressor. Raver1 acts as a PTB corepressor for splicing of alpha-tropomyosin (Tpm1) exon 3. Here we define a minimal region of Raver1 that acts as a repressor domain when recruited
Autor:
Alexis P Rideau, Justine Southby, Nicholas J. McGlincy, Fiona Robinson, Matthew C Wollerton, Arianne J. Matlin, Sushma Nagaraja Grellscheid, Clare Gooding, Christopher W.J. Smith, R. Spellman
Publikováno v:
Biochemical Society transactions. 33(Pt 3)
PTB (polypyrimidine tract-binding protein) is a repressive regulator of alternative splicing. We have investigated the role of PTB in three model alternative splicing systems. In the α-actinin gene, PTB represses the SM (smooth muscle) exon by bindi
Autor:
A. D. J. Scadden, Justine Southby, Clare Gooding, Alexis P Rideau, Robert H. Singer, Stefan Hüttelmaier, Christopher W.J. Smith, Natalia Gromak
Publikováno v:
The EMBO journal. 22(23)
Regulated switching of the mutually exclusive exons 2 and 3 of alpha-tropomyosin (TM) involves repression of exon 3 in smooth muscle cells. Polypyrimidine tract-binding protein (PTB) is necessary but not sufficient for regulation of TM splicing. Rave