Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Alexis Nolte"'
Autor:
Hans-Georg Eichler, Alexis Nolte, Guido Rasi, Xavier Kurz, Sabine M. J. M. Straus, Peter Arlett
Publikováno v:
European Journal of Internal Medicine. 83:6-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f804b4ad54a0fe9598ca6cb59052862
https://doi.org/10.1016/j.ejim.2020.11.019
https://doi.org/10.1016/j.ejim.2020.11.019
Publikováno v:
Biochemistry. 38:3157-3167
The splicing process catalyzed by group II intron ribozymes follows the same two-step pathway as nuclear pre-mRNA splicing. In vivo, the first splicing step of wild-type introns is a transesterification reaction giving rise to a branched lariat intro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d925c98b113d17a184168d70f495786a
https://doi.org/10.1021/bi982462j
https://doi.org/10.1021/bi982462j
Publikováno v:
Nature Biotechnology. 14:1116-1119
The high affinity and selectivity of nucleic acid ligands have clearly demonstrated that RNA can be targeted to a variety of molecules. In practice, however, the use of unmodified aptamers is impeded by the low stability of RNA in biological fluids.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58dd409c681616a6dcf0ebbe36887c1f
https://doi.org/10.1038/nbt0996-1116
https://doi.org/10.1038/nbt0996-1116
Publikováno v:
Brain Research. 660:144-153
The short- and long-term consequences of a neonatal exposure to diazepam (DZP) on the postnatal changes in local cerebral metabolic rates for glucose (LCMRglcs) were studied by the quantitative autoradiographic [14C]2-deoxyglucose method in a total n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d715ccbf8f9f1dfce787758a6203be
https://doi.org/10.1016/0006-8993(94)90848-6
https://doi.org/10.1016/0006-8993(94)90848-6
Autor:
Isabelle Moulon, Francesco Pignatti, Nirosha Amerasinghe, Alexis Nolte, Daniel Gustafsson, Marisa Papaluca Amati, Patrick Le Courtois
Publikováno v:
Journal of Biomedicine and Biotechnology
Journal of Biomedicine and Biotechnology, Vol 2003, Iss 1, Pp 3-8 (2003)
Journal of Biomedicine and Biotechnology, Vol 2003, Iss 1, Pp 3-8 (2003)
The evaluation of quality, safety, and efficacy of medicinal products by the European Medicines Evaluation Agency (EMEA) via the centralized procedure is the only available regulatory procedure for obtaining marketing authorization for gene therapy (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::774fbec4a4919801812f62d853204f24
https://pubmed.ncbi.nlm.nih.gov/12686717
https://pubmed.ncbi.nlm.nih.gov/12686717
Publikováno v:
RNA (New York, N.Y.). 4(6)
Substrate sequences surrounding catalytic RNAs but not involved in specific, conserved interactions can severely interfere with in vitro ribozyme activity. Using model group II intron precursor transcripts with truncated or randomized exon sequences,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b40cb38f95610cc90fede3d9d919c40
https://pubmed.ncbi.nlm.nih.gov/9622128
https://pubmed.ncbi.nlm.nih.gov/9622128
Publikováno v:
Nature biotechnology. 14(9)
A 58-mer L-RNA ligand that binds to naturally occurring D-adenosine with a dissociation constant of 1.7 microM in solution was identified from a combinatorial library employing mirror-design. The corresponding D-RNA ligand shows identical binding aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34551f9494417f96cbf0d308e14fc8e3
https://pubmed.ncbi.nlm.nih.gov/9631061
https://pubmed.ncbi.nlm.nih.gov/9631061
Autor:
Volker A. Erdmann, Keith S. Wilson, Sven Kluβman, Rolf Bald, Alexis Nolte, Zbigniev Dauter, Siegfried Lorenz, Jens P. Fürste, Christian Betzel
Publikováno v:
FEBS Letters. (2):292-294
The ribosomal 5S RNA is an essential constituent of the large ribosomal subunit. To overcome the difficulties of crystallizing large RNA molecules such as 5S rRNAs, we decided to divide the 5S rRNA in five domains A through E to determine their struc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d8c907aabaa7a28f44826efe60eaf90