Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Alexis Nolfi"'
Publikováno v:
Journal of Clinical and Translational Science, Vol 2, Pp 1-2 (2018)
OBJECTIVES/SPECIFIC AIMS: Pelvic organ prolapse, a disorder in which the muscles of the pelvic floor are weakened over time, affects over a million women each year in the United States. A quarter of these women undergo a reconstructive procedure, inc
Externí odkaz:
https://doaj.org/article/f9ba3a42ae5c44f48db5b4f442b8ad68
Publikováno v:
Current Pathobiology Reports. 8:111-120
Functional angiogenesis is a critical therapeutic goal in many pathological conditions. Logically, the use of pro-angiogenic growth factors has been the mainstay approach despite obvious limitations and modest success. Recently, macrophages have been
Autor:
Aimon Iftikhar, Bryan N. Brown, Clint D. Skillen, Samuel T. LoPresti, Daniel Hachim, Yuta U. Umeda, Alexis Nolfi, Rahul D. Rege
Publikováno v:
Biomater Sci
The host macrophage response to implants has shown to be affected by tissue location and physio-pathological conditions of the patient. Success in immunomodulatory strategies is thus predicated on the proper understanding of the macrophage population
Autor:
Clint D. Skillen, Shweta Ravichandar, Aimon Iftikhar, Bryan N. Brown, Alexis Nolfi, Samuel T. LoPresti, Daniel Hachim
Publikováno v:
J Control Release
The role of innate immunity and macrophages in the host response to biomaterials has received renewed attention. A context-dependent spectrum of macrophage phenotypes are shown to affect tissue integration and performance of implanted biomaterials an
Autor:
Alexis Nolfi, Buckenmeyer Mj, Steimer, Meena Sukhwani, Case Zw, Antonio D'Amore, Xian Z, Bryan N. Brown, Aimon Iftikhar, Kyle E. Orwig, Dadi S
Female cancer patients who have undergone chemotherapy have an elevated risk of developing premature ovarian failure (POF) and infertility. Experimental approaches to treat iatrogenic infertility are evolving rapidly; however, there remain challenges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::298996aaab8d094fde058306be9a7866
https://doi.org/10.1101/2020.01.03.893941
https://doi.org/10.1101/2020.01.03.893941
Engineering ethics often takes the classical approach of preventive ethics. That is, engineering ethics most commonly focuses upon safety and regulation in an attempt to prevent the failure of future products. Such approaches generally rely on sets o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1c37be266a7b7ca177d2552ed104427
https://doi.org/10.1016/b978-0-12-816137-1.00098-2
https://doi.org/10.1016/b978-0-12-816137-1.00098-2
Publikováno v:
Menopause. 23:129-137
OBJECTIVE Some selective estrogen receptor modulators (SERMs) have been associated with increased incidence of urinary incontinence and pelvic organ prolapse. This study explored the effects of five SERMs on the function and matrix components of the
Publikováno v:
Journal of Clinical and Translational Science
OBJECTIVES/SPECIFIC AIMS: Pelvic organ prolapse, a disorder in which the muscles of the pelvic floor are weakened over time, affects over a million women each year in the United States. A quarter of these women undergo a reconstructive procedure, inc
Autor:
Alexis Nolfi, William R. Barone, Stacy Palcsey, Katrina Knight, Pamela Moalli, Steven D. Abramowitch
Parity is the leading risk factor for the development of pelvic organ prolapse. To assess the impact of pregnancy and delivery on vaginal tissue, researchers commonly use nonhuman primate (NHP) and rodent models. The purpose of this study was to eval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf334a3a4248551e5fb866256c32073
https://europepmc.org/articles/PMC5201171/
https://europepmc.org/articles/PMC5201171/
Autor:
William R. Barone, Katrina Knight, Steven D. Abramowitch, Pamela A. Moalli, Robert W. Powers, Stacy Palcsey, Alexis Nolfi, Rui Liang
Publikováno v:
Obstetrical & Gynecological Survey. 72:277-278
The use of wide pore lightweight polypropylene mesh to improve anatomical outcomes in the surgical repair of prolapse has been hampered by mesh complications. One of the prototype prolapse meshes has been found to negatively impact the vagina by indu