Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alexis Lainoff"'
Autor:
Melissa McCartney, Adam B. Roddy, John Geiger, Natalia C. Piland, Melina M. Ribeiro, Alexis Lainoff
Publikováno v:
Journal of Microbiology & Biology Education, Vol 23, Iss 1 (2022)
ABSTRACT As educators, we should not assume that students are progressing toward intended STEM careers simply because they have persisted and received a STEM degree. In addition to learning biology content and scientific skills, students need guidanc
Externí odkaz:
https://doaj.org/article/191bf2b6b5c9475a85a7603b00c3e531
Untangling Sources of Phenotypic Variation Characterizing the Craniofacial Disease Holoprosencephaly
Publikováno v:
The FASEB Journal. 32
Autor:
Ralph S. Marcucio, Aki Kallonen, Diane Hu, Alexis Lainoff, Jacqueline E. Moustakas-Verho, Leslea J. Hlusko
Publikováno v:
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution. 324:255-269
A well-known tenet of murine tooth development is that BMP4 and FGF8 antagonistically initiate odontogenesis, but whether this tenet is conserved across amniotes is largely unexplored. Moreover, changes in BMP4-signaling have previously been implicat
Autor:
Heather A. Jamniczky, Alexis Lainoff, Ralph S. Marcucio, Nathan M. Young, Benedikt Hallgrímsson, Francis J. Smith, Emin Maltepe, Diane Hu
Publikováno v:
Disease Models & Mechanisms
Disease Models & Mechanisms, Vol 6, Iss 4, Pp 915-924 (2013)
Disease Models & Mechanisms, Vol 6, Iss 4, Pp 915-924 (2013)
SummaryCraniofacial anomalies can arise from both genetic and environmental factors, including prenatal hypoxia. Recent clinical evidence correlates hypoxia to craniofacial malformations. However, the mechanisms by which hypoxia mediates these defect
Autor:
Benedikt Hallgrímsson, Alexis Lainoff, Jennifer Wong, Ralph S. Marcucio, Katherine A. Brakora, Yolanda Ho, Siew-Ging Gong
Publikováno v:
The FASEB Journal. 29
Mutations in FgfR2 cause several craniosynostosis syndromes, including Crouzon Syndrome (CS), but knowledge of the specific mechanisms by which FGF effects morphogenesis is lacking. The gene CRISPL...
Autor:
Kathleen K. Smith, Ralph S. Marcucio, Keijo Hämäläinen, Diane Hu, Leslea J. Hlusko, Aki Kallonen, Alexis Lainoff, Jacqueline Moustakas
Publikováno v:
The FASEB Journal. 28
It is a well-known tenet of murine tooth development that BMP4 and FGF8 antagonistically initiate odontogenesis, but it is largely unexplored whether this tenet is conserved across amniotes. Additionally, changes in BMP4-signaling have previously bee
Autor:
Alexis Lainoff, Raul E. Diaz, Richard A. Schneider, Nathan M. Young, Diane Hu, Ralph S. Marcucio, Paul A. Trainor, Francis J. Smith, Abigail S. Tucker, Benedikt Hallgrímsson
Publikováno v:
Development (Cambridge, England), vol 141, iss 5
Young, NM; Hu, D; Lainoff, AJ; Smith, FJ; Diaz, R; Tucker, AS; et al.(2014). Embryonic bauplans and the developmental origins of facial diversity and constraint. Development (Cambridge), 141(5), 1059-1063. doi: 10.1242/dev.099994. UCSF: Retrieved from: http://www.escholarship.org/uc/item/7d59010w
Young, NM; Hu, D; Lainoff, AJ; Smith, FJ; Diaz, R; Tucker, AS; et al.(2014). Embryonic bauplans and the developmental origins of facial diversity and constraint. Development (Cambridge), 141(5), 1059-1063. doi: 10.1242/dev.099994. UCSF: Retrieved from: http://www.escholarship.org/uc/item/7d59010w
A central issue in biology concerns the presence, timing and nature of phylotypic periods of development, but whether, when and why species exhibit conserved morphologies remains unresolved. Here, we construct a developmental morphospace to show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a187d96dc0a33ff9b1e5872a88ab816
https://europepmc.org/articles/PMC3929406/
https://europepmc.org/articles/PMC3929406/
Publikováno v:
The FASEB Journal. 27