Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Alexis Jiaying Khng"'
Autor:
Peh Joo Ho, Alexis Jiaying Khng, Benita Kiat-Tee Tan, Geok Hoon Lim, Su-Ming Tan, Veronique Kiak Mien Tan, Ryan Shea Ying Cong Tan, Elaine Hsuen Lim, Philip Tsau-Choong Iau, Ying Jia Chew, Yi Ying Lim, Mikael Hartman, Ern Yu Tan, Jingmei Li
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-12 (2023)
Abstract Background Exposure to cytotoxic chemotherapy treatment may alter DNA methylation (DNAm) in breast cancer patients. Methods We performed DNAm analysis in 125 breast cancer patients with blood drawn before and after chemotherapy, using the Il
Externí odkaz:
https://doaj.org/article/08fa501a0a194a4dbf1009ccbbf6f46f
Autor:
Seeu Si Ong, Peh Joo Ho, Alexis Jiaying Khng, Benita Kiat Tee Tan, Qing Ting Tan, Ern Yu Tan, Su-Ming Tan, Thomas Choudary Putti, Swee Ho Lim, Ee Ling Serene Tang, Jingmei Li, Mikael Hartman
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 9058 (2024)
Idiopathic granulomatous mastitis (IGM) is a rare condition characterised by chronic inflammation and granuloma formation in the breast. The aetiology of IGM is unclear. By focusing on the protein-coding regions of the genome, where most disease-rela
Externí odkaz:
https://doaj.org/article/15da0dc941084098bed9cad45b2399d7
Autor:
Zi Lin Lim, Peh Joo Ho, Alexis Jiaying Khng, Yen Shing Yeoh, Amanda Tse Woon Ong, Benita Kiat Tee Tan, Ern Yu Tan, Su-Ming Tan, Geok Hoon Lim, Jung Ah Lee, Veronique Kiak-Mien Tan, Jesse Hu, Jingmei Li, Mikael Hartman
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-19 (2022)
Abstract Background Early detection of breast cancer (BC) through mammography screening (MAM) is known to reduce mortality. We examined the differential effect that mammography has on BC characteristics and overall survival and the sociodemographic d
Externí odkaz:
https://doaj.org/article/e03983852e9340cdad3977127b36f817
Autor:
Shannon N. Fenlon, Yuemin Celina Chee, Jacqueline Lai Yuen Chee, Yeen Hui Choy, Alexis Jiaying Khng, Lu Ting Liow, Kurosh S. Mehershahi, Xiaoan Ruan, Stephen W. Turner, Fei Yao, Swaine L. Chen
Publikováno v:
BMC Research Notes, Vol 13, Iss 1, Pp 1-4 (2020)
Abstract Objectives The availability of matched sequencing data for the same sample across different sequencing platforms is a necessity for validation and effective comparison of sequencing platforms. A commonly sequenced sample is the lab-adapted M
Externí odkaz:
https://doaj.org/article/89e4205a8e704411b57759ce092259ff
Autor:
Jenny Liu, Peh Joo Ho, Tricia Hui Ling Tan, Yen Shing Yeoh, Ying Jia Chew, Nur Khaliesah Mohamed Riza, Alexis Jiaying Khng, Su-Ann Goh, Yi Wang, Han Boon Oh, Chi Hui Chin, Sing Cheer Kwek, Zhi Peng Zhang, Desmond Luan Seng Ong, Swee Tian Quek, Chuan Chien Tan, Hwee Lin Wee, Jingmei Li, Philip Tsau Choong Iau, Mikael Hartman
Publikováno v:
PLoS ONE, Vol 17, Iss 3, p e0265965 (2022)
Routine mammography screening is currently the standard tool for finding cancers at an early stage, when treatment is most successful. Current breast screening programmes are one-size-fits-all which all women above a certain age threshold are encoura
Externí odkaz:
https://doaj.org/article/1440624a9fef47aab02ac5e1448dc873
Autor:
Seeu Si Ong, Jia Xu, Choon Kiat Sim, Alexis Jiaying Khng, Peh Joo Ho, Philip Kam Weng Kwan, Aarthi Ravikrishnan, Kiat-Tee Benita Tan, Qing Ting Tan, Ern Yu Tan, Su-Ming Tan, Thomas Choudary Putti, Swee Ho Lim, Ee Ling Serene Tang, Niranjan Nagarajan, Neerja Karnani, Jingmei Li, Mikael Hartman
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1042 (2023)
Idiopathic granulomatous mastitis (IGM) is a rare and benign inflammatory breast disease with ambiguous aetiology. Contrastingly, lactational mastitis (LM) is commonly diagnosed in breastfeeding women. To investigate IGM aetiology, we profiled the mi
Externí odkaz:
https://doaj.org/article/2049130e9512420db439bba516c66098
Autor:
Xingang Wang, Zhonghua Zhao, Julius Muller, Audrey Iyu, Alexis Jiaying Khng, Ernesto Guccione, Yijun Ruan, Philip W. Ingham
Publikováno v:
Biology Open, Vol 2, Iss 11, Pp 1203-1213 (2013)
Summary Hedgehog (Hh) signaling is mediated by the Gli transcription factors and, in the zebrafish, plays an important role in patterning both the neural tube and myotome. Using a null allele of the gli2a gene induced by targeted mutagenesis, we show
Externí odkaz:
https://doaj.org/article/f7b661713b1b4e9091fb245de27f8812
Autor:
Daniel S.W. Tan, Anders J. Skanderup, Axel M. Hillmer, Weiwei Zhai, Eng-Huat Tan, Wai Leong Tam, N. Gopalakrishna Iyer, Wan-Teck Lim, Chee Keong Toh, Lisda Suteja, Ming Jie Lim, Alexis Jiaying Khng, Audrey S.M. Teo, Lanying Wang, Yin Yeng Lee, Bien Soo Tan, Ghee Chee Phua, Devanand Anantham, Tanujaa Rajasekaran, Mei Kim Ang, Quan Sing Ng, Ravindran Kanesvaran, Chow Wei Too, Apoorva Gogna, Wan Ling Tan, Amit Jain, Irfahan Kassam, Marjan Mojtabavi Naeini, Kiat Hon Lim, Joe P.S. Yeong, Zaw Win Aung, Gillianne G.Y. Lai, Neha Rohatgi, Rahul Nahar, Jacob J.S. Alvarez, Angela Takano, Aaron C. Tan, Yvonne H.F. Teng, Khi Pin Chua
Purpose:Despite the established role of EGFR tyrosine kinase inhibitors (TKIs) in EGFR-mutated NSCLC, drug resistance inevitably ensues, with a paucity of treatment options especially in EGFRT790M-negative resistance.Experimental Design:We performed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::227b720107cfdf35e476c0479af15bbd
https://doi.org/10.1158/1078-0432.c.6530516.v1
https://doi.org/10.1158/1078-0432.c.6530516.v1
Autor:
Daniel S.W. Tan, Anders J. Skanderup, Axel M. Hillmer, Weiwei Zhai, Eng-Huat Tan, Wai Leong Tam, N. Gopalakrishna Iyer, Wan-Teck Lim, Chee Keong Toh, Lisda Suteja, Ming Jie Lim, Alexis Jiaying Khng, Audrey S.M. Teo, Lanying Wang, Yin Yeng Lee, Bien Soo Tan, Ghee Chee Phua, Devanand Anantham, Tanujaa Rajasekaran, Mei Kim Ang, Quan Sing Ng, Ravindran Kanesvaran, Chow Wei Too, Apoorva Gogna, Wan Ling Tan, Amit Jain, Irfahan Kassam, Marjan Mojtabavi Naeini, Kiat Hon Lim, Joe P.S. Yeong, Zaw Win Aung, Gillianne G.Y. Lai, Neha Rohatgi, Rahul Nahar, Jacob J.S. Alvarez, Angela Takano, Aaron C. Tan, Yvonne H.F. Teng, Khi Pin Chua
Supplementary Data from Integrative Profiling of T790M-Negative EGFR-Mutated NSCLC Reveals Pervasive Lineage Transition and Therapeutic Opportunities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166d4b020fca17d01eb4115553cc3afd
https://doi.org/10.1158/1078-0432.22480715
https://doi.org/10.1158/1078-0432.22480715
Autor:
Seeu Si Ong, Jia Xu, Choon Kiat Sim, Alexis Jiaying Khng, Peh Joo Ho, Philip Kam Weng Kwan, Aarthi Ravikrishnan, Kiat-Tee Benita Tan, Qing Ting Tan, Ern Yu Tan, Su-Ming Tan, Thomas Choudary Putti, Swee Ho Lim, Ee Ling Serene Tang, Niranjan Nagarajan, Neerja Karnani, Jingmei Li, Mikael Hartman
BackgroundIdiopathic granulomatous mastitis (IGM) is a rare, chronic, and benign inflammatory breast disease with ambiguous aetiology. Contrastingly, lactational mastitis (LM) is commonly diagnosed in breastfeeding women. To investigate IGM aetiology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5fc6c60b03f0ea5782442241eb6937c
https://doi.org/10.1101/2022.09.30.510425
https://doi.org/10.1101/2022.09.30.510425