Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Alexis J. Carulli"'
Autor:
Elizabeth A. Carlson, Alexis J. Carulli, Iannis Aifantis, Natacha Bohin, Jennifer C. Jones, Constance D. Brindley, Martin G. Myers, Christian W. Siebel, Michael Rajala, Jie Gao, Theresa M. Keeley, Emily M. Walker, Linda C. Samuelson, Peter J. Dempsey
Publikováno v:
Stem Cell Reports
Summary Intestinal crypts have great capacity for repair and regeneration after intestinal stem cell (ISC) injury. Here, we define the cellular remodeling process resulting from ISC niche interruption by transient Notch pathway inhibition in adult mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61f6ad6d10e02065450ad4a36e87456c
http://europepmc.org/articles/PMC7363878
http://europepmc.org/articles/PMC7363878
Autor:
Peter J. Dempsey, Elizabeth A. Carlson, Alexis J. Carulli, Michael Rajala, Martin G. Myers, Theresa M. Keeley, Linda C. Samuelson, Constance D. Brindley, Iannis Aifantis, Jie Gao, Natacha Bohin, Jennifer Jones
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0344046c0aaec9866cf7f50a76c83217
https://doi.org/10.1096/fasebj.2018.32.1_supplement.612.2
https://doi.org/10.1096/fasebj.2018.32.1_supplement.612.2
Autor:
Zhenyi Liu, Kelli L. VanDussen, Theresa M. Keeley, Alexis J. Carulli, Raphael Kopan, Gail B. Gifford, Linda C. Samuelson, Dafydd G. Thomas, Elise S. Demitrack, Thomas J. Giordano
Publikováno v:
The EMBO Journal. 34:2522-2536
The major signaling pathways regulating gastric stem cells are unknown. Here we report that Notch signaling is essential for homeostasis of LGR5(+) antral stem cells. Pathway inhibition reduced proliferation of gastric stem and progenitor cells, whil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9296c34fd15f4c5f63e1cad6c989682c
https://doi.org/10.15252/embj.201490583
https://doi.org/10.15252/embj.201490583
Autor:
Jooho Chung, Elise S. Demitrack, Alexis J. Carulli, Theresa M. Keeley, Linda C. Samuelson, Ivan Maillard
Publikováno v:
Developmental Biology. 402(1):98-108
The Notch signaling pathway regulates intestinal epithelial cell homeostasis, including stem cell maintenance, progenitor cell proliferation and differentiation. Notch1 and Notch2 receptors are expressed in the epithelium, but individual contribution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65c62d11e7e356b3cfb1d957da13c9b5
Publikováno v:
The FASEB Journal. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b96289e3303eccffa0404d469f8aa96
https://doi.org/10.1096/fasebj.28.1_supplement.899.4
https://doi.org/10.1096/fasebj.28.1_supplement.899.4
Publikováno v:
Integrative biology : quantitative biosciences from nano to macro. 6(3)
The definition, regulation and function of intestinal stem cells (ISCs) has been hotly debated. Recent discoveries have started to clarify the nature of ISCs, but many questions remain. This review discusses the current advances and controversies of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57d013854ad63c3a4c93eab4f11aab2b
https://pubmed.ncbi.nlm.nih.gov/24480852
https://pubmed.ncbi.nlm.nih.gov/24480852
Autor:
Alexis J. Carulli
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 305(11)
The federal sequester has exacerbated an already grim research funding crisis. The continued budget cuts have had a widespread effect on all researchers in biomedical science, but the impact is especially keen on trainees who are deciding whether or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d81e38899a1bc19e7c61890fe5dc764d
https://pubmed.ncbi.nlm.nih.gov/24091597
https://pubmed.ncbi.nlm.nih.gov/24091597
Publikováno v:
Gastroenterology. 150:S170
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82a0225dc27d2878fbe5a459d52a19e8
https://doi.org/10.1016/s0016-5085(16)30661-8
https://doi.org/10.1016/s0016-5085(16)30661-8
Autor:
Ivan Maillard, Amy L. Shelton, Christian W. Siebel, Ann Friedman, Christen L. Ebens, Linda C. Samuelson, Vedran Radojcic, Gloria T. Shan, Alexis J. Carulli, Minhong Yan, Jooho Chung, Ivy T. Tran, Pavan Reddy, Thomas Gridley, Ashley R. Sandy
Publikováno v:
The Journal of clinical investigation. 123(4)
Graft-versus-host disease (GVHD) is the main complication of allogeneic bone marrow transplantation. Current strategies to control GVHD rely on global immunosuppression. These strategies are incompletely effective and decrease the anticancer activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8317711d67eb8d05ab50308ec97d1c
https://pubmed.ncbi.nlm.nih.gov/23454750
https://pubmed.ncbi.nlm.nih.gov/23454750
Autor:
Åsa Kolterud, Yu Hwai Tsai, Deborah L. Gumucio, Peter J. Dempsey, Ivy T. Tran, Kelli L. VanDussen, Theresa M. Keeley, Scott T. Magness, Ivan Maillard, Brent J. Puthoff, Christian W. Siebel, Alexis J. Carulli, Linda C. Samuelson, Sanjeevkumar R. Patel, Ann S. Grosse, Stephen A. Ernst
Publikováno v:
Development (Cambridge, England). 139(3)
Notch signaling is known to regulate the proliferation and differentiation of intestinal stem and progenitor cells; however, direct cellular targets and specific functions of Notch signals had not been identified. We show here in mice that Notch dire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ceeb81ed3b328c7862fecac8a52c5e2
https://pubmed.ncbi.nlm.nih.gov/22190634
https://pubmed.ncbi.nlm.nih.gov/22190634