Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Alexis H. Onimus"'
Autor:
Grace A. Ward, Robert P. Dalton, Benjamin S. Meyer, Amy F. McLemore, Amy L. Aldrich, Nghi B. Lam, Alexis H. Onimus, Nicole D. Vincelette, Thu Le Trinh, Xianghong Chen, Alexandra R. Calescibetta, Sean M. Christiansen, Hsin-An Hou, Joseph O. Johnson, Kenneth L. Wright, Eric Padron, Erika A. Eksioglu, Alan F. List
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 4
Pages: 3896
Volume 24
Issue 4
Pages: 3896
Myelodysplastic Syndromes (MDSs) are bone marrow (BM) failure malignancies characterized by constitutive innate immune activation, including NLRP3 inflammasome driven pyroptotic cell death. We recently reported that the danger-associated molecular pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24296941692008624ba442455615683c
Autor:
Alexis H Onimus, Nicole D. Vincelette, Erika A. Eksioglu, Hsin-An Hou, Amy F McLemore, Farnoosh Abbas-Aghababazadeh, Kathy L. McGraw, Benjamin S. Meyer, Alan F. List, Alexandra Calescibetta, Grace A Ward, Thu Le Trinh, Sheng Wei
Publikováno v:
Blood. 132:3076-3076
Constitutive innate immune activation is a pathogenetic driver of Myelodysplastic Syndromes (MDS) that directs ineffective hematopoiesis by NLRP3 inflammasome (IFM) assembly and pyroptotic cell death. IFM activation involves recruitment of caspase-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed2838a63a2525522c4a95790619e060
https://doi.org/10.1182/blood-2018-99-118493
https://doi.org/10.1182/blood-2018-99-118493
Autor:
Benjamin S. Meyer, Nicole D. Vincelette, Ling Zhang, Matthew A. Rodrigues, Alan F. List, Amy F McLemore, Sheng Wei, Kathy L. McGraw, Erika A. Eksioglu, Hsin-An Hou, Alexis H Onimus, Neelkamal Chaudhary, Grace A Ward
Publikováno v:
Blood. 132:3075-3075
Background: The pathogenesis of Myelodysplastic Syndromes (MDS) is linked to constitutive innate immune stimulation that converges upon the NLRP3 inflammasome to induce pyroptosis, a caspase-1 dependent cell death. We have shown that inflammasome ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcfcd4bd90c7f480a1c7126ceca1745b
https://doi.org/10.1182/blood-2018-99-116929
https://doi.org/10.1182/blood-2018-99-116929