Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Alexis Gervais"'
Autor:
Lauren E. Boucher, Elisabeth Geyer Prinslow, Michael Feldkamp, Fang Yi, Rupesh Nanjunda, Sheng-Jiun Wu, Tun Liu, Eilyn R. Lacy, Steven Jacobs, Natalia Kozlyuk, Brian Del Rosario, Bingyuan Wu, Patricia Aquino, Robert C. Davidson, Samantha Heyne, Nicholas Mazzanti, James Testa, Michael D. Diem, Elsa Gorre, Andrew Mahan, Hirsh Nanda, Harsha P. Gunawardena, Alexis Gervais, Anthony A. Armstrong, Alexey Teplyakov, Chichi Huang, Adam Zwolak, Partha Chowdhury, Wan Cheung Cheung, Jinquan Luo
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTSingle-chain fragment variable (scFv) domains play an important role in antibody-based therapeutic modalities, such as bispecifics, multispecifics and chimeric antigen receptor T cells or natural killer cells. However, scFv domains exhibit lo
Externí odkaz:
https://doaj.org/article/07a49e5767d741f0bc24b50e3af689e1
Autor:
Sandra Santulli-Marotto, Alexis Gervais, Jamie Fisher, Brandy Strake, Carol Anne Ogden, Chelsea Riveley, Jill Giles-Komar
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145078 (2015)
Defective clearance of apoptotic cells can result in sustained inflammation and subsequent autoimmunity. Macrophages, the "professional phagocyte" of the body, are responsible for efficient, non-phlogistic, apoptotic cell clearance. Controlling phago
Externí odkaz:
https://doaj.org/article/121c70eecd334f97b1f6fa2901ad517d
Autor:
Susan H. Tam, Stephen G. McCarthy, Anthony A. Armstrong, Sandeep Somani, Sheng-Jiun Wu, Xuesong Liu, Alexis Gervais, Robin Ernst, Dorina Saro, Rose Decker, Jinquan Luo, Gary L. Gilliland, Mark L. Chiu, Bernard J. Scallon
Publikováno v:
Antibodies, Vol 6, Iss 3, p 12 (2017)
Engineering of fragment crystallizable (Fc) domains of therapeutic immunoglobulin (IgG) antibodies to eliminate their immune effector functions while retaining other Fc characteristics has numerous applications, including blocking antigens on Fc gamm
Externí odkaz:
https://doaj.org/article/e4effcd57176409f88ce8c9b266a42aa
Autor:
Dorina Saro, Susan H. Tam, Sandeep Somani, Mark L. Chiu, Bernard Scallon, Alexis Gervais, Gary L. Gilliland, Xuesong Liu, Sheng-Jiun Wu, Rose Decker, Stephen G. McCarthy, Jinquan Luo, Robin Ernst, Anthony A. Armstrong
Publikováno v:
Antibodies, Vol 6, Iss 3, p 12 (2017)
Antibodies; Volume 6; Issue 3; Pages: 12
Antibodies
Antibodies; Volume 6; Issue 3; Pages: 12
Antibodies
Engineering of fragment crystallizable (Fc) domains of therapeutic immunoglobulin (IgG) antibodies to eliminate their immune effector functions while retaining other Fc characteristics has numerous applications, including blocking antigens on Fc gamm
Autor:
Alexis Gervais, Jamie Fisher, Sandra Santulli-Marotto, Brandy Strake, Carol Anne Ogden, Chelsea Riveley, Jill Giles-Komar
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 12, p e0145078 (2015)
PLoS ONE, Vol 10, Iss 12, p e0145078 (2015)
Defective clearance of apoptotic cells can result in sustained inflammation and subsequent autoimmunity. Macrophages, the "professional phagocyte" of the body, are responsible for efficient, non-phlogistic, apoptotic cell clearance. Controlling phago