Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alexis D Dunkle"'
Autor:
Dina R. Weilhammer, Alexis D. Dunkle, Tyler Boone, Sean F. Gilmore, Mark Khemmani, Sandra K. G. Peters, Paul D. Hoeprich, Nicholas O. Fischer, Craig D. Blanchette, Adam Driks, Amy Rasley
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Subunit vaccines are theoretically safe and easy to manufacture but require effective adjuvants and delivery systems to yield protective immunity, particularly at critical mucosal sites such as the lung. We investigated nanolipoprotein particles (NLP
Externí odkaz:
https://doaj.org/article/ca91e8ee57e54aeda6984465ee70cda7
Autor:
Dina, Weilhammer, Alexis D, Dunkle, Craig D, Blanchette, Nicholas O, Fischer, Michele, Corzett, Doerte, Lehmann, Tyler, Boone, Paul, Hoeprich, Adam, Driks, Amy, Rasley
Publikováno v:
Vaccine. 35(11)
To address the need for vaccine platforms that induce robust cell-mediated immunity, we investigated the potential of utilizing self-assembling biologic nanolipoprotein particles (NLPs) as an antigen and adjuvant delivery system to induce antigen-spe
Autor:
Dina R Weilhammer, Alexis D Dunkle, Craig Blanchette, Tyler Boone, Sean Gilmore, Michele Corzett, Nicholas Fischer, Doerte Lehmann, Cheri Lychak, Paul Hoeprich, Adam Driks, Amy Rasley
Publikováno v:
The Journal of Immunology. 196:145.3-145.3
There is considerable interest in developing a novel Bacillus anthracis vaccine that improves upon the shortcomings of the licensed vaccine for broader, more rapid protection of the population. Ideally, a vaccine would recognize the spore in addition
Publikováno v:
The Journal of Immunology. 182:84.19-84.19
T cells depend on the careful regulation of apoptosis for normal development, homeostasis and immune response. The Bcl-2 family of proteins has been shown to play critical roles regulating T cell apoptotic pathways. The anti-apoptotic proteins Bcl-2