Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Alexis Christoforides"'
Autor:
Mitesh J. Borad, Jan B. Egan, Rachel M. Condjella, Winnie S. Liang, Rafael Fonseca, Nicole R. Ritacca, Ann E. McCullough, Michael T. Barrett, Katherine S. Hunt, Mia D. Champion, Maitray D. Patel, Scott W. Young, Alvin C. Silva, Thai H. Ho, Thorvardur R. Halfdanarson, Robert R. McWilliams, Konstantinos N. Lazaridis, Ramesh K. Ramanathan, Angela Baker, Jessica Aldrich, Ahmet Kurdoglu, Tyler Izatt, Alexis Christoforides, Irene Cherni, Sara Nasser, Rebecca Reiman, Lori Cuyugan, Jacquelyn McDonald, Jonathan Adkins, Stephen D. Mastrian, Riccardo Valdez, Dawn E. Jaroszewski, Daniel D. Von Hoff, David W. Craig, A. Keith Stewart, John D. Carpten, Alan H. Bryce
Publikováno v:
Scientific Reports, Vol 6, Iss 1, Pp 1-12 (2016)
Abstract DNA focused panel sequencing has been rapidly adopted to assess therapeutic targets in advanced/refractory cancer. Integrated Genomic Profiling (IGP) utilising DNA/RNA with tumour/normal comparisons in a Clinical Laboratory Improvement Amend
Externí odkaz:
https://doaj.org/article/0d55a397502a4dbe956a6fd30cff0c29
Autor:
David M. Engelthaler, Tom M. Chiller, James A. Schupp, Joshua Colvin, Stephen M. Beckstrom-Sternberg, Elizabeth M. Driebe, Tracy Moses, Waibhav Tembe, Shripad Sinari, James S. Beckstrom-Sternberg, Alexis Christoforides, John V. Pearson, John Carpten, Paul Keim, Ashley Peterson, Dawn Terashita, S. Arunmozhi Balajee
Publikováno v:
Emerging Infectious Diseases, Vol 17, Iss 2, Pp 227-232 (2011)
Next-generation sequencing enables use of whole-genome sequence typing (WGST) as a viable and discriminatory tool for genotyping and molecular epidemiologic analysis. We used WGST to confirm the linkage of a cluster of Coccidioides immitis isolates f
Externí odkaz:
https://doaj.org/article/37aeda4400f6416eae12e0ceeb5547b3
Autor:
Mitesh J Borad, Mia D Champion, Jan B Egan, Winnie S Liang, Rafael Fonseca, Alan H Bryce, Ann E McCullough, Michael T Barrett, Katherine Hunt, Maitray D Patel, Scott W Young, Joseph M Collins, Alvin C Silva, Rachel M Condjella, Matthew Block, Robert R McWilliams, Konstantinos N Lazaridis, Eric W Klee, Keith C Bible, Pamela Harris, Gavin R Oliver, Jaysheel D Bhavsar, Asha A Nair, Sumit Middha, Yan Asmann, Jean-Pierre Kocher, Kimberly Schahl, Benjamin R Kipp, Emily G Barr Fritcher, Angela Baker, Jessica Aldrich, Ahmet Kurdoglu, Tyler Izatt, Alexis Christoforides, Irene Cherni, Sara Nasser, Rebecca Reiman, Lori Phillips, Jackie McDonald, Jonathan Adkins, Stephen D Mastrian, Pamela Placek, Aprill T Watanabe, Janine Lobello, Haiyong Han, Daniel Von Hoff, David W Craig, A Keith Stewart, John D Carpten
Publikováno v:
PLoS Genetics, Vol 10, Iss 2, p e1004135 (2014)
Advanced cholangiocarcinoma continues to harbor a difficult prognosis and therapeutic options have been limited. During the course of a clinical trial of whole genomic sequencing seeking druggable targets, we examined six patients with advanced chola
Externí odkaz:
https://doaj.org/article/72d9a122f58441d9a86d9254c686cd3b
Autor:
Glen J Weiss, Winnie S Liang, Michael J Demeure, Jeff A Kiefer, Galen Hostetter, Tyler Izatt, Shripad Sinari, Alexis Christoforides, Jessica Aldrich, Ahmet Kurdoglu, Lori Phillips, Hollie Benson, Rebecca Reiman, Angela Baker, Vickie Marsh, Daniel D Von Hoff, John D Carpten, David W Craig
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76438 (2013)
New anticancer agents that target a single cell surface receptor, up-regulated or amplified gene product, or mutated gene, have met with some success in treating advanced cancers. However, patients' tumors still eventually progress on these therapies
Externí odkaz:
https://doaj.org/article/280c1289dfac456ab2cd5e066758e4d2
Genome-wide characterization of pancreatic adenocarcinoma patients using next generation sequencing.
Autor:
Winnie S Liang, David W Craig, John Carpten, Mitesh J Borad, Michael J Demeure, Glen J Weiss, Tyler Izatt, Shripad Sinari, Alexis Christoforides, Jessica Aldrich, Ahmet Kurdoglu, Michael Barrett, Lori Phillips, Hollie Benson, Waibhav Tembe, Esteban Braggio, Jeffrey A Kiefer, Christophe Legendre, Richard Posner, Galen H Hostetter, Angela Baker, Jan B Egan, Haiyong Han, Douglas Lake, Edward C Stites, Ramesh K Ramanathan, Rafael Fonseca, A Keith Stewart, Daniel Von Hoff
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e43192 (2012)
Pancreatic adenocarcinoma (PAC) is among the most lethal malignancies. While research has implicated multiple genes in disease pathogenesis, identification of therapeutic leads has been difficult and the majority of currently available therapies prov
Externí odkaz:
https://doaj.org/article/8bbd106cd51d413ca0f1e24b592ba757
Autor:
Glen J Weiss, Winnie S Liang, Tyler Izatt, Shilpi Arora, Irene Cherni, Robert N Raju, Galen Hostetter, Ahmet Kurdoglu, Alexis Christoforides, Shripad Sinari, Angela S Baker, Raghu Metpally, Waibhav D Tembe, Lori Phillips, Daniel D Von Hoff, David W Craig, John D Carpten
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37029 (2012)
Olfactory neuroblastoma (ONB) is a rare cancer of the sinonasal tract with little molecular characterization. We performed whole genome sequencing (WGS) on paired normal and tumor DNA from a patient with metastatic-ONB to identify the somatic alterat
Externí odkaz:
https://doaj.org/article/4e2340d80321458c9712eae24d4a2f0f
Autor:
John D. Carpten, Daniel Von Hoff, Spyro Mousses, Jeffrey M. Trent, Anthony W. Tolcher, Bodour Salhia, Paul R. Billings, Linh Hoang, Asim Siddiqui, Francisco M. De La Vega, Onur Sakarya, Catalin Barbacioru, Julie Koeman, Angela Baker, Ahmet Kurdoglu, Tyler Izatt, Cynthia R. Osborne, Cristi L. Aitelli, Joanne L. Blum, Alexis Christoforides, Jennifer Dinh, Shukmei Wong, Tracy M. Moses, Shripad Sinari, Jessica Aldrich, Jeffrey A. Kiefer, Joyce A. O'Shaughnessy, David W. Craig
XLSX file - 45K, Genes containing breakpoint from translocation in mTNBC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::030c3b3040f73e2498710e2987260e51
https://doi.org/10.1158/1535-7163.22498330
https://doi.org/10.1158/1535-7163.22498330
Autor:
John D. Carpten, Daniel Von Hoff, Spyro Mousses, Jeffrey M. Trent, Anthony W. Tolcher, Bodour Salhia, Paul R. Billings, Linh Hoang, Asim Siddiqui, Francisco M. De La Vega, Onur Sakarya, Catalin Barbacioru, Julie Koeman, Angela Baker, Ahmet Kurdoglu, Tyler Izatt, Cynthia R. Osborne, Cristi L. Aitelli, Joanne L. Blum, Alexis Christoforides, Jennifer Dinh, Shukmei Wong, Tracy M. Moses, Shripad Sinari, Jessica Aldrich, Jeffrey A. Kiefer, Joyce A. O'Shaughnessy, David W. Craig
XLSX file - 273K, Somatic genic focal copy number changes in mTNBC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::976e7ded660565e7e60ad54bf30e551b
https://doi.org/10.1158/1535-7163.22498333.v1
https://doi.org/10.1158/1535-7163.22498333.v1
Autor:
John D. Carpten, Daniel Von Hoff, Spyro Mousses, Jeffrey M. Trent, Anthony W. Tolcher, Bodour Salhia, Paul R. Billings, Linh Hoang, Asim Siddiqui, Francisco M. De La Vega, Onur Sakarya, Catalin Barbacioru, Julie Koeman, Angela Baker, Ahmet Kurdoglu, Tyler Izatt, Cynthia R. Osborne, Cristi L. Aitelli, Joanne L. Blum, Alexis Christoforides, Jennifer Dinh, Shukmei Wong, Tracy M. Moses, Shripad Sinari, Jessica Aldrich, Jeffrey A. Kiefer, Joyce A. O'Shaughnessy, David W. Craig
XLSX file - 598K, edgeR differential expression results in mTNBC for select cancer related genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e995e6477189c39c5a4d0dc4dddb516
https://doi.org/10.1158/1535-7163.22498348
https://doi.org/10.1158/1535-7163.22498348
Autor:
John D. Carpten, Daniel Von Hoff, Spyro Mousses, Jeffrey M. Trent, Anthony W. Tolcher, Bodour Salhia, Paul R. Billings, Linh Hoang, Asim Siddiqui, Francisco M. De La Vega, Onur Sakarya, Catalin Barbacioru, Julie Koeman, Angela Baker, Ahmet Kurdoglu, Tyler Izatt, Cynthia R. Osborne, Cristi L. Aitelli, Joanne L. Blum, Alexis Christoforides, Jennifer Dinh, Shukmei Wong, Tracy M. Moses, Shripad Sinari, Jessica Aldrich, Jeffrey A. Kiefer, Joyce A. O'Shaughnessy, David W. Craig
XLSX file - 607K, Outlier differential expression results in mTNBC for select cancer related genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::113d5cac8cd491de5211004eb0279aa7
https://doi.org/10.1158/1535-7163.22498342
https://doi.org/10.1158/1535-7163.22498342