Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Alexis Chery"'
Autor:
Francesca Castoldi, Juliette Humeau, Isabelle Martins, Sylvie Lachkar, Damarys Loew, Florent Dingli, Sylvère Durand, David Enot, Noëlie Bossut, Alexis Chery, Fanny Aprahamian, Yohann Demont, Paule Opolon, Nicolas Signolle, Allan Sauvat, Michaela Semeraro, Lucillia Bezu, Elisa Elena Baracco, Erika Vacchelli, Jonathan G. Pol, Sarah Lévesque, Norma Bloy, Valentina Sica, Maria Chiara Maiuri, Guido Kroemer, Federico Pietrocola
Publikováno v:
Cell Death Discovery, Vol 6, Iss 1, Pp 1-17 (2020)
Abstract Salicylate, the active derivative of aspirin (acetylsalicylate), recapitulates the mode of action of caloric restriction inasmuch as it stimulates autophagy through the inhibition of the acetyltransferase activity of EP300. Here, we directly
Externí odkaz:
https://doaj.org/article/87cf4e0d739f46b498bf36f527c63889
Autor:
Valentina Sica, Jose Manuel Bravo-San Pedro, Valentina Izzo, Jonathan Pol, Sandra Pierredon, David Enot, Sylvère Durand, Noélie Bossut, Alexis Chery, Sylvie Souquere, Gerard Pierron, Evangelia Vartholomaiou, Naoufal Zamzami, Thierry Soussi, Allan Sauvat, Laura Mondragón, Oliver Kepp, Lorenzo Galluzzi, Jean-Claude Martinou, Holger Hess-Stumpp, Karl Ziegelbauer, Guido Kroemer, Maria Chiara Maiuri
Publikováno v:
Cell Reports, Vol 27, Iss 3, Pp 820-834.e9 (2019)
Summary: Inhibition of oxidative phosphorylation (OXPHOS) by 1-cyclopropyl-4-(4-[(5-methyl-3-(3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl)-1H-pyrazol-1-yl)methyl]pyridin-2-yl)piperazine (BAY87-2243, abbreviated as B87), a complex I inhibitor,
Externí odkaz:
https://doaj.org/article/2e77a726e5534371a4b12359e5c7bfd6
Autor:
Francesca Castoldi, Jelena Tadic, Katharina Kainz, Maria Chiara Maiuri, Elisa E. Baracco, David Enot, Alexis Chery, V. Izzo, Frank Madeo, Sylvère Durand, Guido Kroemer, Federico Pietrocola
Publikováno v:
Aging (Albany NY)
The metabolite α-ketoglutarate is membrane-impermeable, meaning that it is usually added to cells in the form of esters such as dimethyl α-ketoglutarate (DMKG), trifluoromethylbenzyl α-ketoglutarate (TFMKG) and octyl α-ketoglutarate (O-KG). Once
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8156940b0cd422c0d232b1583310d698
http://hdl.handle.net/11588/840485
http://hdl.handle.net/11588/840485
Autor:
Alexis Chery, Sylvère Durand, Lorenzo Galluzzi, Federico Pietrocola, Frank Madeo, Guido Kroemer, Erika Vacchelli, David Enot, Mireia Niso-Santano
Publikováno v:
Cell Cycle. 14:2399-2407
Recently, we reported that saturated and unsaturated fatty acids trigger autophagy through distinct signal transduction pathways. Saturated fatty acids like palmitate (PA) induce autophagic responses that rely on phosphatidylinositol 3-kinase, cataly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4040bca3f26d6b350f4ed06acea7b09
https://doi.org/10.1080/15384101.2015.1064206
https://doi.org/10.1080/15384101.2015.1064206
Autor:
Guido Kroemer, Valentina Astesana, Maria Castedo, Federico Pietrocola, Alexis Chery, Adrien Joseph, Jonathan Pol, Judith Michels, Sarah Levesque, Sylvère Durand, Florine Obrist, Gen Sheng Wu
Publikováno v:
The EMBO journal. 37(14)
Cisplatin is the most widely used chemotherapeutic agent, and resistance of neoplastic cells against this cytoxicant poses a major problem in clinical oncology. Here, we explored potential metabolic vulnerabilities of cisplatin-resistant non-small hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::944fb8750abdb03737b2c861eb2f7101
https://pubmed.ncbi.nlm.nih.gov/29875131
https://pubmed.ncbi.nlm.nih.gov/29875131
Autor:
Guido Kroemer, Didier Métivier, Frank Madeo, Michaela Semeraro, Francesca Castoldi, Chloé Bordenave, David Enot, Sylvère Durand, Federico Pietrocola, M. Chiara Maiuri, Yohann Demont, Alexis Chery, Juliette Humeau, Sarah Levesque, Jonathan Pol, Elisa E. Baracco, José Manuel Bravo-San Pedro
Publikováno v:
Autophagy. 13(3)
Starvation is a strong physiological stimulus of macroautophagy/autophagy. In this study, we addressed the question as to whether it would be possible to measure autophagy in blood cells after nutrient deprivation. Fasting of mice for 48 h (which cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec98824f4ad720a2a5d0aa3f1e59a7f1
https://pubmed.ncbi.nlm.nih.gov/28059587
https://pubmed.ncbi.nlm.nih.gov/28059587
Autor:
Sylvie Lachkar, Guido Kroemer, Alexis Chery, Valeria Raia, Speranza Esposito, Sylvère Durand, Maria Chiara Maiuri, José Manuel Bravo-San Pedro, David Enot, Federico Pietrocola, Valentina Sica, Luigi Maiuri, V. Izzo
Phase II clinical trials indicate that the combination of cysteamine plus epigallocatechin gallate (EGCG) is effective against cystic fibrosis in patients bearing the most frequent etiological mutation (CFTRΔF508). Here, we investigated the interact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e1bda664b30206cea0ecf715f271ce
http://hdl.handle.net/11588/681032
http://hdl.handle.net/11588/681032
Autor:
Valentina Sica, Frank Madeo, Norma Bloy, Maria Chiara Maiuri, Erika Vacchelli, David Enot, Fernando Aranda, Laura Senovilla, Jonathan Pol, Sarah Levesque, Nicolas Jacquelot, Elisa E. Baracco, Laurence Zitvogel, Lionel Apetoh, Guillermo Mariño, Takahiro Yamazaki, Francesca Castoldi, Aitziber Buqué, Josef M. Penninger, Bernhard Ryffel, Simonetta Falzoni, Beth Levine, Verena Sigl, Sylvère Durand, Sylvie Lachkar, Francesco Di Virgilio, Alexis Chery, Guido Kroemer, Shuan Rao, Federico Pietrocola
Publikováno v:
Cancer Cell
Cancer Cell, 2016, 30 (1), pp.147-160. ⟨10.1016/j.ccell.2016.05.016⟩
Cancer Cell, Elsevier, 2016, 30 (1), pp.147-160. ⟨10.1016/j.ccell.2016.05.016⟩
Cancer Cell, Elsevier, 2016, 30 (1), pp.147-160. 〈http://www.sciencedirect.com/science/article/pii/S1535610816302215〉. 〈10.1016/j.ccell.2016.05.016〉
Cancer Cell, 2016, 30 (1), pp.147-160. ⟨10.1016/j.ccell.2016.05.016⟩
Cancer Cell, Elsevier, 2016, 30 (1), pp.147-160. ⟨10.1016/j.ccell.2016.05.016⟩
Cancer Cell, Elsevier, 2016, 30 (1), pp.147-160. 〈http://www.sciencedirect.com/science/article/pii/S1535610816302215〉. 〈10.1016/j.ccell.2016.05.016〉
International audience; Caloric restriction mimetics (CRMs) mimic the biochemical effects of nutrient deprivation by reducing lysine acetylation of cellular proteins, thus triggering autophagy. Treatment with the CRM hydroxycitrate, an inhibitor of A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb1e9b3e16c0fcd6614d5624f9636177
https://u-bourgogne.hal.science/hal-01431196
https://u-bourgogne.hal.science/hal-01431196
Publikováno v:
Methods in enzymology. 543
Quantitative proteomics approaches have been developed-and now begin to be implemented on a high-throughput basis-to fill-in the large gap between the genomic/transcriptomic setup of (cancer) cells and their phenotypic/behavioral traits, reflecting a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e5cd35b0b48bbbfe3c16c5c673bc4e2c
https://pubmed.ncbi.nlm.nih.gov/24924132
https://pubmed.ncbi.nlm.nih.gov/24924132
Quantitative proteomics approaches have been developed-and now begin to be implemented on a high-throughput basis-to fill-in the large gap between the genomic/transcriptomic setup of (cancer) cells and their phenotypic/behavioral traits, reflecting a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cfcd32325c0888942c7e4e60e3f2a00
https://doi.org/10.1016/b978-0-12-801329-8.00008-8
https://doi.org/10.1016/b978-0-12-801329-8.00008-8