Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Alexis Agelan"'
Publikováno v:
Drug Delivery Letters. 2:14-21
Autor:
Mohan P. Achary, Brigitte Gordon, Nadia Bakdash, Alexis Agelan, Yuchuan Liu, Yajue Huang, Robert W. Colman, Robin A. Pixley, Sabina T. Khan
Publikováno v:
Cancer Immunology, Immunotherapy. 59:1885-1893
Metastasis of malignant tumors is a major cause of morbidity and mortality. Inhibition of tumor growth in distant organs is of clinical importance. We have demonstrated that C11C1, a murine monoclonal antibody to the light chain region of high molecu
Autor:
Garnik G. Akopian, Ka Hung Lee, Alexis Agelan, Kim Phuong Thi Nguyen, Diana S. Woodruff-Pak, Michael R. Foy, Jordan Zach, John A. Kennard, Richard F. Thompson, David M. Comalli
Publikováno v:
Proceedings of the National Academy of Sciences. 107:1624-1629
Cognitive functions show many alternative outcomes and great individual variation during normal aging. We examined learning over the adult life span in CBA mice, along with morphological and electrophysiological substrates. Our aim was to compare cer
Autor:
Marco Cassone, Károly Nagy, Ferenc Rozgonyi, Béla Kocsis, Paul Bart Noto, Laszlo Otvos, Dóra Szabó, Giovanni Abbadessa, Alexis Agelan, George Mateo, John D. Wade
Publikováno v:
Protein Science. 17:1249-1255
The proline-rich designer antibacterial peptide dimer A3-APO is currently under preclinical development for the treatment of systemic infections caused by antibiotic-resistant Gram-negative bacteria. The peptide showed remarkable stability in 25% mou
Autor:
Irma Isordia-Salas, Robert W. Colman, Robin A. Pixley, Raul A. DeLa Cadena, Julian L. Castaneda, Albert Adam, Irma M. Sainz, Alexis Agelan, Bo Liu, R. Balfour Sartor
Publikováno v:
Arthritis & Rheumatism. 52:2549-2552
Objective To compare inflammatory peripheral arthritis in wild-type and high molecular weight kininogen (HK)–deficient rats, both on the genetically susceptible Lewis background. Methods By backcrossing Brown-Norway HK-deficient rats with Lewis rat
Autor:
Irma M. Sainz, Audrey B. Uknis, Robert W. Colman, Albert Adam, Walter K. Long, Robin A. Pixley, Alexis Agelan, John P. Gaughan, Irma Isordia-Salas, Raul A. DeLa Cadena, Ricardo G. Espinola
Publikováno v:
The American Journal of Pathology. 165:969-976
We reported that high-molecular weight kininogen is proangiogenic by releasing bradykinin and that a monoclonal antibody to high-molecular weight kininogen, C11C1, blocked its binding to endothelial cells. We now test if this antibody can prevent art
Publikováno v:
Biochemistry. 41:2014-2021
Two highly homologous dimeric disintegrins, CC5 and CC8, have been isolated from the venom of the North African sand viper Cerastes cerastes. CC5 is a homodimer containing an RGD motif in its subunits. CC8 is a heterodimer. The CC8A and CC8B subunits
Publikováno v:
Electromagnetic Biology and Medicine. 21:303-308
Millimeter wave therapy has been reported to reduce the toxic side effects of chemo- and radiation therapy in the treatment of cancer. In order to understand the mechanisms involved in this reduction, the effect of millimeter electromagnetic waves (M
Autor:
Viviana Zuluaga, Yi Wu, Robert W. Colman, Alexis Agelan, Daniel J. Sexton, Aizhen Yang, Jihong Dai
Publikováno v:
Arthritis and rheumatism. 64(11)
Objective To examine whether activation of the plasma kallikrein–kinin system (KKS) mediates synovial recruitment of endothelial progenitor cells (EPCs) in arthritis. Methods EPCs were isolated from Lewis rat bone marrow, and expression of progenit
Autor:
Chiara Lucchetti, Alexis Agelan, Robert Fratamico, Flavio Rizzolio, Valentina Tomei, Gaia Gallo, Isabella Caligiuri, Andres J. Klein-Szanto, Antonio Giordano, Giovanni Ferrari, Giuseppe Toffoli
Publikováno v:
Journal of cellular physiology. 228(1)
The activity of the Retinoblastoma protein, the master regulator of the cell cycle, is finely regulated by phosphorylation. CDKs and cyclins are major players in phosphorylation and it has been recently discovered that the prolyl isomerase Pin1 is an