Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Alexia Vite"'
Autor:
Rachel Truitt, PhD, Anbin Mu, Elise A. Corbin, PhD, Alexia Vite, PhD, Jeffrey Brandimarto, PhD, Bonnie Ky, MD, MSCE, Kenneth B. Margulies, MD
Publikováno v:
JACC: Basic to Translational Science, Vol 3, Iss 2, Pp 265-276 (2018)
Summary: Sunitinib, a multitargeted oral tyrosine kinase inhibitor, used widely to treat solid tumors, results in hypertension in up to 47% and left ventricular dysfunction in up to 19% of treated individuals. The relative contribution of afterload t
Externí odkaz:
https://doaj.org/article/8a7b6c28cc9d40ae987798036a3109ae
Autor:
Carissa Livingston, Abhinay Ramachandran, Elise Corbin, Alexia Vite, Alexander Bennett, Kenneth Margulies
Publikováno v:
Journal of Clinical and Translational Science, Vol 3, Pp 114-115 (2019)
OBJECTIVES/SPECIFIC AIMS: The aims of this study are threefold. Firstly, we are examining the effects of increased in vitro afterload (a proxy for hypertension) on human induced pluripotent stem cell cardiomyocyte (hiPSC-CM) response to sunitinib in
Externí odkaz:
https://doaj.org/article/a04e61c0dbf048ddb5e2d7305732319a
Autor:
Abhinay Ramachandran, Carissa Livingston, Elise Corbin, Alexia Vite, Alex Bennett, Kenneth Margulies
Publikováno v:
Journal of Clinical and Translational Science, Vol 3, Pp 9-9 (2019)
OBJECTIVES/SPECIFIC AIMS: This project aims to determine the key molecular pathways that link increased myocardial wall stress to cardiomyocyte hypertrophy and subsequent heart failure. We will use a cardiac microtissue (CMT) model with dynamically t
Externí odkaz:
https://doaj.org/article/f1e47140cdaf4bae9124cb86e292d54d
Autor:
Alexia Vite, Estelle Gandjbakhch, Catherine Prost, Veronique Fressart, Pierre Fouret, Nathalie Neyroud, Françoise Gary, Erwan Donal, Shaida Varnous, Guy Fontaine, Paul Fornes, Françoise Hidden-Lucet, Michel Komajda, Philippe Charron, Eric Villard
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75082 (2013)
AimsArrhythmogenic right ventricular Dysplasia/cardiomyopathy (ARVD/C) is an autosomal dominant inherited cardiomyopathy associated with ventricular arrhythmia, heart failure and sudden death. Genetic studies have demonstrated the central role of des
Externí odkaz:
https://doaj.org/article/9481c6636b114f2897675fe8e5931f3a
Autor:
Abhinay Ramachandran, Carissa E. Livingston, Alexia Vite, Elise A. Corbin, Alexander I. Bennett, Kevin T. Turner, Benjamin W. Lee, Chi Keung Lam, Joseph C. Wu, Kenneth B. Margulies
Publikováno v:
Journal of Cardiovascular Translational Research.
Autor:
Alexia Vite, Matthew A. Caporizzo, Elise A. Corbin, Jeffrey Brandimarto, Quentin McAfee, Carissa E. Livingston, Benjamin L. Prosser, Kenneth B. Margulies
Publikováno v:
Basic Res Cardiol
The mechanical environment of the myocardium has a potent effect on cardiomyocyte form and function, yet an understanding of the cardiomyocyte responses to extracellular stiffening remains incomplete. We therefore employed a cell culture substrate wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b354dcd3a2782812f06a5f9072de730
https://europepmc.org/articles/PMC9899517/
https://europepmc.org/articles/PMC9899517/
Autor:
Vasiliki Courelli, Keita Uchida, Alexia Vite, Benjamin Prosser, Kenneth Margulies, Michael Ibrahim
Publikováno v:
Journal of Molecular and Cellular Cardiology. 173:138-139
Publikováno v:
Circulation Research. 129
Due to its high energy consumption and limited ability to store ATP, the heart is highly dependent of exogenous metabolic substrates. Prior in vivo studies have reported that the development of heart failure is accompanied by a transition from the no
Autor:
Kiran Musunuru, Xiao Wang, Alexander I. Bennett, Kenneth B. Margulies, Xuemei Cheng, Jeffrey Brandimarto, Alexia Vite, Myan Bhoopalam, Eliot G. Peyster, Elise A. Corbin, Kevin T. Turner, Andy T. Clark
Publikováno v:
ACS Applied Materials & Interfaces. 11:20603-20614
New directions in material applications have allowed for the fresh insight into the coordination of biophysical cues and regulators. Although the role of the mechanical microenvironment on cell responses and mechanics is often studied, most analyses
Autor:
Alex Caplan, Emmanuel S. Buys, Ingrid Marti-Pamies, Patrick Seale, Alexia Vite, Jesus Tamez, Marielle Scherrer-Crosbie, Lauren Graves, Robrecht Thoonen, Wei Han, Daniel Bloch
Publikováno v:
Am J Physiol Endocrinol Metab
Bone morphogenetic protein (BMP) receptor signaling is critical for the regulation of the endocrine system and cardiovascular structure and function. The objective of this study was to investigate whether Bmp3b, a glycoprotein synthetized and secrete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88384738233a380b4bbc9abdfb39eaf6
https://europepmc.org/articles/PMC7473912/
https://europepmc.org/articles/PMC7473912/