Výsledky vyhledávání - "Alexia Karvela"

Novel combined insulin-like 3 variations of a single nucleotide in cryptorchidism

Autor: Roza Mourelatou, Andrea-Paola Rojas-Gil, Xenophon Sinopidis, Efstathia Tsekoura, George Georgiou, Eirini Kostopoulou, Bessie E. Spiliotis, Alexia Karvela

Publikováno v: Journal of Pediatric Endocrinology and Metabolism. 32:987-994

BackgroundInsulin-like 3 hormone (INSL3) is involved in the process of testicular descent, and has been thoroughly studied in cryptorchidism. However, INSL3 allelic variations found in the human genome were heterozygous and only a few of them were fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::299ccbc8e9a7801e196dabc79e45592e
https://doi.org/10.1515/jpem-2018-0547

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Metabolic Association between Leptin and the Corticotropin Releasing Hormone

Autor: Iason Thomas, Andrea Paola Rojas-Gil, Alexia Karvela, Athanasia Mouzaki, Sofia Gioldasi, Bessie E. Spiliotis, Anne-Lise de Lastic, Maria Rodi

Publikováno v: Endocrine, Metabolic & Immune Disorders Drug Targets

Results and Conclusion:The available data indicate that CRH exerts a role in the regulation of leptin in human adipocytes. We show that CRH downregulates leptin production by mature adipocytes and that a strong negative correlation exists between CRH

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08242a2cdc31f65849cfb6e1f3626da7
https://doi.org/10.2174/1871530319666190206165626

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Adiponectin Signaling and Impaired GTPase Rab5 Expression in Adipocytes of Adolescents with Obesity

Autor: Bessie E. Spiliotis, Aikaterini Avgeri, Eirini Kostopoulou, Jesús Argente, Andrea Paola Rojas Gil, George Lambrinidis, Ioannis Dimopoulos, George Georgiou, Aliki Pappa, Alexia Karvela, Vicente Barrios

Publikováno v: Hormone research in paediatrics. 93(5)

Introduction: Abnormalities in adipose tissue AdipoR1; adaptor protein, phosphotyrosine interaction, PH domain, and leucine zipper containing 1 (APPL1); GTPase Rab5; adiponectin; leptin; and visfatin in adults with obesity have been associated with m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0410455f1c58e478bed5f9ed6cefa93e
https://pubmed.ncbi.nlm.nih.gov/33075770

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Epidermal growth factor receptor (EGFR) involvement in successful growth hormone (GH) signaling in GH transduction defect

Autor: Alexia Karvela, Bessie E. Spiliotis, Eirini Kostopoulou, Andrea Paola Rojas-Gil

Publikováno v: Journal of Pediatric Endocrinology and Metabolism. 30

Background:Growth hormone (GH) transduction defect (GHTD) is a growth disorder with impaired signal transducer and activator of transcription 3 (STAT3) phosphorylation mediated by overexpression of cytokine-inducible SH2-containing protein (CIS), whi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da05b2a852040e9f5b50a89c65a946e8
https://doi.org/10.1515/jpem-2016-0189

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Protective mechanisms against oxidative stress and angiopathy in young patients with diabetes type 1 (DM1)

Autor: Nikolitsa Koutroumani, Andrea Paola Rojas Gil, Ioanna Partsalaki, Eirini Kostopoulou, Bessie E. Spiliotis, Athina Dettoraki, Alexia Karvela, Fotini N. Lamari

Publikováno v: Journal of pediatric endocrinologymetabolism : JPEM. 26(3-4)

Objective Advanced glycation end-products (AGEs) via their receptor, RAGE, are involved in diabetic angiopathy. Soluble RAGE, an inhibitor of this axis, is formed by enzymatic catalysis (sRAGE) or alternative splicing (esRAGE). Malondialdehyde (MDA)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c2c6d0b98390d0f059b8f4ef9ff0aae
https://pubmed.ncbi.nlm.nih.gov/23337054

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Metabolic impact of a ketogenic diet compared to a hypocaloric diet in obese children and adolescents

Autor: Ioanna Partsalaki, Alexia Karvela, Bessie E. Spiliotis

Publikováno v: Journal of Pediatric Endocrinology and Metabolism. 25

Background The effects of carbohydrate-restricted (ketogenic) diets on metabolic parameters in children have been incompletely assessed. Objective To compare the efficacy and metabolic impact of ketogenic and hypocaloric diets in obese children and a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cfd64340013b519e1fc41d9767eb435
https://doi.org/10.1515/jpem-2012-0131

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Endocannabinoid (EC) Receptor, CB1, and EC Enzymes' Expression in Primary Adipocyte Cultures of Lean and Obese Pre-pubertal Children in Relation to Adiponectin and Insulin

Autor: George Georgiou, Andrea Paola Rojas-Gil, Bessie E. Spiliotis, Efstratia Samkinidou, Helen Papadaki, Alexia Karvela, Aliki Pappa

Publikováno v: Journal of Pediatric Endocrinology and Metabolism. 23

AIM The over-expression of CB1 in adult obesity is associated with insulin resistance (IR),but it is not elucidated in childhood obesity. We studied CB1 and endocannabinoid enzymes (EE), Adiponectin (Ad), and Insulin (SI) in lean and obese pre-pubert

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0c073188b9bf70647a8833e84f4cad2
https://doi.org/10.1515/jpem.2010.162

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