Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Alexia Karen, Cotte"'
Autor:
Michèle Beniey, Audrey Hubert, Takrima Haque, Alexia Karen Cotte, Nelly Béchir, Xiaomeng Zhang, Danh Tran-Thanh, Saima Hassan
Publikováno v:
British Journal of Cancer. 128:1964-1975
Background Patients with triple-negative breast cancer (TNBC) develop early recurrence. While PARP inhibitors (PARPi) have demonstrated potential in BRCA1/2-mutant (BRCAMUT) TNBC, durable responses will likely be achieved if PARPi are used in combina
Autor:
Alexia Karen Cotte, Virginie Aires, Maxime Fredon, Emeric Limagne, Valentin Derangère, Marion Thibaudin, Etienne Humblin, Alessandra Scagliarini, Jean-Paul Pais de Barros, Patrick Hillon, François Ghiringhelli, Dominique Delmas
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Lipid droplets (LD) accumulation correlates with colorectal cancer (CRC) relapse. Here the authors show that chemotherapy induces LD synthesis via acyltransferase LPCAT2 which, in turn, promotes chemoresistance via LD accumulation both in vitro and i
Externí odkaz:
https://doaj.org/article/ebbb44a3f0364d6cb5aecb457ae581a2
Publikováno v:
Molecular & Cellular Oncology, Vol 5, Iss 3 (2018)
Lipid droplets (LD) are now-well recognized as playing a role in cancer progression, however their potential role in chemoresistance remains largely unknown, particularly in colorectal cancer (CRC). We recently highlighted that LD accumulate in CRC c
Externí odkaz:
https://doaj.org/article/9000032af48e4fccb395f82ac04468d6
Autor:
Etienne Humblin, Virginie Aires, Valentin Derangère, Marion Thibaudin, Patrick Hillon, Maxime Fredon, Alessandra Scagliarini, Dominique Delmas, Jean-Paul Pais de Barros, Emeric Limagne, Alexia Karen Cotte, François Ghiringhelli
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.322. ⟨10.1038/s41467-017-02732-5⟩
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.322. 〈https://www.nature.com/articles/s41467-017-02732-5〉. 〈10.1038/s41467-017-02732-5〉
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.322. ⟨10.1038/s41467-017-02732-5⟩
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.322. 〈https://www.nature.com/articles/s41467-017-02732-5〉. 〈10.1038/s41467-017-02732-5〉
Lipid droplet (LD) accumulation is a now well-recognised hallmark of cancer. However, the significance of LD accumulation in colorectal cancer (CRC) biology is incompletely understood under chemotherapeutic conditions. Since drug resistance is a majo
Autor:
Alexia Karen, Cotte, Vanessa, Cottet, Virginie, Aires, Thomas, Mouillot, Maud, Rizk, Sandrine, Vinault, Christine, Binquet, Jean-Paul Pais, de Barros, Patrick, Hillon, Dominique, Delmas
Publikováno v:
Oncotarget
Background Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Phospholipids are now well-recognised players in tumour progression. Their metabolic tissue alterations can be associated with plasmatic modifications. The aim of th
Autor:
Angélique Chevriaux, Romain Boidot, Sylvain Ladoire, François Ghiringhelli, Flavie Courtaut, Valentin Derangère, Mickaël Rialland, Laurent Arnould, Alexia Karen Cotte, Cédric Rébé
Publikováno v:
Oncotarget
Increasing evidence indicates that Liver X Receptors (LXRs) have some anticancer properties. We recently demonstrated that LXR ligands induce colon cancer cell pyroptosis through an LXRβ-dependent pathway. In the present study, we showed that human
Autor:
Emeric Limagne, François Ghiringhelli, Virginie Aires, Alessandra Scagliarini, Didier J. Colin, Alexia Karen Cotte, Dominique Delmas
Publikováno v:
Annals of the New York Academy of Sciences. 1290:90-97
The preventive effects of the phytoalexin trans-resveratrol toward cancer have been largely described at the cellular and molecular levels in both in vivo and in vitro models; however, its primary targets are still poorly identified. In this review,
Autor:
Emeric Limagne, Alexia Karen Cotte, Patrick Hillon, Norbert Latruffe, Samia Hamza, Dominique Delmas, Vanessa Cottet
Publikováno v:
Hepatology
Hepatology, Wiley-Blackwell, 2014, 60 (3), pp.1110-1111. ⟨10.1002/hep.27004⟩
Hepatology, Wiley-Blackwell, 2014, 60 (3), pp.1110-1111. ⟨10.1002/hep.27004⟩
International audience
Autor:
Dominique Delmas, François Ghiringhelli, Alexia Karen Cotte, Virginie Aires, Norbert Latruffe, Emeric Limagne
Publikováno v:
Molecular nutritionfood research. 57(7)
Scope Resveratrol (RSV) has been proposed to prevent tumor growth; nevertheless, these preventive effects are controversial since RSV pharmacokinetics studies show a low bioavailability. Recent clinical trials show that patients with colorectal cance