Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Alexia Conte"'
Autor:
Roberta Pascolutti, Veronica Algisi, Alexia Conte, Andrea Raimondi, Mithun Pasham, Srigokul Upadhyayula, Raphael Gaudin, Tanja Maritzen, Elisa Barbieri, Giusi Caldieri, Chiara Tordonato, Stefano Confalonieri, Stefano Freddi, Maria Grazia Malabarba, Elena Maspero, Simona Polo, Carlo Tacchetti, Volker Haucke, Tom Kirchhausen, Pier Paolo Di Fiore, Sara Sigismund
Publikováno v:
Cell Reports, Vol 43, Iss 11, Pp 114970- (2024)
Externí odkaz:
https://doaj.org/article/b2ea199df0684449960748dac3c283bb
Autor:
Roberta Pascolutti, Veronica Algisi, Alexia Conte, Andrea Raimondi, Mithun Pasham, Srigokul Upadhyayula, Raphael Gaudin, Tanja Maritzen, Elisa Barbieri, Giusi Caldieri, Chiara Tordonato, Stefano Confalonieri, Stefano Freddi, Maria Grazia Malabarba, Elena Maspero, Simona Polo, Carlo Tacchetti, Volker Haucke, Tom Kirchhausen, Pier Paolo Di Fiore, Sara Sigismund
Publikováno v:
Cell Reports, Vol 27, Iss 10, Pp 3049-3061.e6 (2019)
Summary: Adaptor protein 2 (AP2) is a major constituent of clathrin-coated pits (CCPs). Whether it is essential for all forms of clathrin-mediated endocytosis (CME) in mammalian cells is an open issue. Here, we demonstrate, by live TIRF microscopy, t
Externí odkaz:
https://doaj.org/article/621ad877eaa14894b7e9f36e39fad5bd
Autor:
Stefano Freddi, Irene Schiano Lomoriello, Alexia Conte, Sara Sigismund, Maura Poli, Elena Gammella, Gaetano Cairo, Alessandra Alberghini, Stefania Recalcati
Publikováno v:
Molecular Biology of the Cell. 32:98-108
The posttranslational regulation of transferrin receptor (TfR1) is largely unknown. We investigated whether iron availability affects TfR1 endocytic cycle and protein stability in HepG2 hepatoma cells exposed to ferric ammonium citrate (FAC). NH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a4b2d3a69aa6fa75a83ebdf0ea7c79a
https://doi.org/10.1091/mbc.e20-02-0129
https://doi.org/10.1091/mbc.e20-02-0129
Autor:
Maria Grazia Malabarba, Pier Paolo Di Fiore, Roberta Pascolutti, Raphael Gaudin, Stefano Freddi, Sara Sigismund, Tanja Maritzen, Srigokul Upadhyayula, Alexia Conte, Elena Maspero, Volker Haucke, Simona Polo, Chiara Tordonato, Veronica Algisi, Mithun Pasham, Stefano Confalonieri, Andrea Raimondi, Elisa Barbieri, Tom Kirchhausen, Carlo Tacchetti, Giusi Caldieri
Publikováno v:
Cell Reports
Cell Reports, Elsevier Inc, 2019, 27 (10), pp.3049-3061.e6. ⟨10.1016/j.celrep.2019.05.017⟩
Cell Reports, Vol 27, Iss 10, Pp 3049-3061.e6 (2019)
Cell Reports, Elsevier Inc, 2019, 27 (10), pp.3049-3061.e6. ⟨10.1016/j.celrep.2019.05.017⟩
Cell Reports, Vol 27, Iss 10, Pp 3049-3061.e6 (2019)
Summary Adaptor protein 2 (AP2) is a major constituent of clathrin-coated pits (CCPs). Whether it is essential for all forms of clathrin-mediated endocytosis (CME) in mammalian cells is an open issue. Here, we demonstrate, by live TIRF microscopy, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fcebed1958c8e5f2827380d175fc662
https://hal.archives-ouvertes.fr/hal-02337347
https://hal.archives-ouvertes.fr/hal-02337347
Autor:
Alexia, Conte, Sara, Sigismund
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1652
Ubiquitination of the epidermal growth factor receptor (EGFR) is an important intracellular signal that occurs upon EGF stimulation and controls EGFR trafficking at multiple steps, finally destining the receptor to lysosomal degradation. In this chap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::44c6a8f1631e0e762b515b1731503f2b
https://pubmed.ncbi.nlm.nih.gov/28791635
https://pubmed.ncbi.nlm.nih.gov/28791635
Autor:
Davide Mazza, Sara Sigismund, Massimo Bonora, Maria Grazia Malabarba, Giusi Caldieri, Tiziana Bonaldi, Alexia Conte, Fabrizio Bianchi, Simona Polo, Emanuele Martini, Andrea Raimondi, Elisa Barbieri, Alessandro Cuomo, Gilda Nappo, Pier Paolo Di Fiore, Lisette G. G. C. Verhoef, Paolo Pinton, Stefano Confalonieri, Carlo Tacchetti
ER-PM contacts in nonclathrin endocytosis The epidermal growth factor receptor (EGFR) is internalized through both clathrin-mediated endocytosis and nonclathrin endocytosis (NCE). The two pathways act in concert to sustain EGFR signaling or its long-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cd7c6d9e4f8f9b303a5490bf8c665cb
http://hdl.handle.net/11392/2382178
http://hdl.handle.net/11392/2382178
Autor:
Sara Sigismund, Alexia Conte
Publikováno v:
Methods in Molecular Biology ISBN: 9781493972180
Ubiquitination of the epidermal growth factor receptor (EGFR) is an important intracellular signal that occurs upon EGF stimulation and controls EGFR trafficking at multiple steps, finally destining the receptor to lysosomal degradation. In this chap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e19c415a908ffc2bec7fc269cbdb3c5
https://doi.org/10.1007/978-1-4939-7219-7_5
https://doi.org/10.1007/978-1-4939-7219-7_5
Autor:
Sara Sigismund, Giuseppe Penna, Elena Magni, Alexia Conte, Alessandro Cuomo, Chiara Pozzi, Maria Giulia Zampino, Paola Simona Ravenda, Alberto Bardelli, Carlotta Cancelliere, Maria Rescigno, Alessio Silvola, Tiziana Bonaldi, Pier Paolo Di Fiore, Ilaria Spadoni
Cetuximab is a monoclonal antibody that is effective in the treatment of metastatic colorectal cancer (mCRC). Cetuximab blocks epidermal growth factor receptor (EGFR)-ligand interaction and inhibits downstream RAS-ERK activation. However, only some a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bbfeb615b5acddfd2e44a7327a03946
http://hdl.handle.net/2318/1622748
http://hdl.handle.net/2318/1622748
Autor:
Sara Sigismund, Fabrizio Capuani, Simona Polo, Alexia Conte, Luca Marchetti, Andrea Ciliberto, Pier Paolo Di Fiore, Corrado Priami, Elisabetta Argenzio
Publikováno v:
Nature Communications
Ubiquitination of the epidermal growth factor receptor (EGFR) that occurs when Cbl and Grb2 bind to three phosphotyrosine residues (pY1045, pY1068 and pY1086) on the receptor displays a sharp threshold effect as a function of EGF concentration. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a00c4e1d3fc690828eef34c97fabdb5
http://hdl.handle.net/11568/881817
http://hdl.handle.net/11568/881817
Autor:
Gilda Nappo, Alexia Conte, Elisabetta Argenzio, Andrea Ciliberto, Tiziana Bonaldi, Veronica Algisi, Sara Sigismund, Fabrizio Capuani, Elena Maspero, Fabrizio Bianchi, Alessandro Cuomo, Simona Polo, Lisette G. G. C. Verhoef, Pier Paolo Di Fiore, Roberta Pascolutti
Publikováno v:
Cell Cycle
How the cell converts graded signals into threshold-activated responses is a question of great biological relevance. Here, we uncover a nonlinear modality of epidermal growth factor receptor (EGFR)-activated signal transduction, by demonstrating that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2df3f2d27d32f9abb870f4a4c40dec2d
https://pubmed.ncbi.nlm.nih.gov/24526125
https://pubmed.ncbi.nlm.nih.gov/24526125