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pro vyhledávání: '"Alexia Abecassis"'
Autor:
Alexia Abecassis, Esther Hermano, Adi Yifrach, Aron Popovtzer, Amichay Meirovitz, Michael Elkin
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive tumor, which is highly resistant to existing therapies and characterized by one of the lowest survival rates known for solid cancers. Among the reasons for this poor prognosis are unique pathop
Externí odkaz:
https://doaj.org/article/4d3661c6891747da8571cd2c3506585d
Autor:
Alexia Abecassis, Esther Hermano, Kim Sheva, Ariel M. Rubinstein, Michael Elkin, Amichay Meirovitz
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 710 (2023)
Agents used to reduce adverse effects common in cancer treatment modalities do not typically possess tumor-suppressing properties. We report that heparanase, an extracellular matrix-degrading enzyme, is a promising candidate for preventing radiation
Externí odkaz:
https://doaj.org/article/5c0c1cee3d764917825166a721740020
Autor:
Rachel Goldberg, Amichay Meirovitz, Alexia Abecassis, Esther Hermano, Ariel M. Rubinstein, Daniela Nahmias, Albert Grinshpun, Tamar Peretz, Michael Elkin
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
While at least six types of cancer have been associated with diabetes, pancreatic ductal adenocarcinoma (PDAC) and diabetes exhibit a unique bidirectional relationship. Recent reports indicate that majority of PDAC patients display hyperglycemia, and
Externí odkaz:
https://doaj.org/article/cc452a2b51dd4ba49b624a298f99b89e
Autor:
Michael Elkin, Esther Hermano, Amichay Meirovitz, Ariel Rubinstein, Israel Vlodavsky, Jin-Ping Li, Ton J. Rabelink, Françoise Carlotti, Alexia Abecassis
Publikováno v:
Cellular and Molecular Life Sciences. SPRINGER BASEL AG
Cellular and Molecular Life Sciences
Cellular and Molecular Life Sciences
Heparanase is the predominant enzyme that cleaves heparan sulfate, the main polysaccharide in the extracellular matrix. While the role of heparanase in sustaining the pathology of autoimmune diabetes is well documented, its association with metabolic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2829ebd73299c09641e8bdddbcfa8a0
https://hdl.handle.net/1887/3184948
https://hdl.handle.net/1887/3184948
