Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Alexia, Kirby"'
Autor:
Nicholas D. Calvert, Alexia Kirby, Mojmír Suchý, Peter Pallister, Aidan A. Torrens, Dylan Burger, Gerd Melkus, Nicola Schieda, Adam J. Shuhendler
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Chronic kidney disease (CKD) and acute kidney injury (AKI) are ongoing global health burdens. Glomerular filtration rate (GFR) is the gold standard measure of kidney function, with clinical estimates providing a global assessment of kidney h
Externí odkaz:
https://doaj.org/article/f5f7b6f5ee5c42b68d9a9e38d99b75b6
Autor:
Alexandria Béland-Millar, Alexia Kirby, Yen Truong, Julie Ouellette, Sozerko Yandiev, Khalil Bouyakdan, Chantal Pileggi, Shama Naz, Melissa Yin, Micaël Carrier, Pavel Kotchetkov, Marie-Kim St-Pierre, Marie-Ève Tremblay, Julien Courchet, Mary-Ellen Harper, Thierry Alquier, Claude Messier, Adam J. Shuhendler, Baptiste Lacoste
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112485- (2023)
Summary: Neurovascular abnormalities in mouse models of 16p11.2 deletion autism syndrome are reminiscent of alterations reported in murine models of glucose transporter deficiency, including reduced brain angiogenesis and behavioral alterations. Yet,
Externí odkaz:
https://doaj.org/article/80b98b8bcdd8414481360ac28e85ff5a
Naked mole-rat brown fat thermogenesis is diminished during hypoxia through a rapid decrease in UCP1
Autor:
Hang Cheng, Rajaa Sebaa, Nikita Malholtra, Baptiste Lacoste, Ziyad El Hankouri, Alexia Kirby, Nigel C. Bennett, Barry van Jaarsveld, Daniel W. Hart, Glenn J. Tattersall, Mary-Ellen Harper, Matthew E. Pamenter
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Naked mole-rats are hypoxia-tolerant mammals, and during hypoxia their body temperature decreases via unknown mechanisms. Here the authors report that the hypoxia-induced body temperature decrease in naked mole rats occurs through decreased brown adi
Externí odkaz:
https://doaj.org/article/a160ac2d7e3742ccace85151b74f2388
Autor:
Eric W. J. Gates, Nicholas D. Calvert, Nicholas J. Cundy, Federica Brugnoli, Pauline Navals, Alexia Kirby, Nicoletta Bianchi, Gautam Adhikary, Adam J. Shuhendler, Richard L. Eckert, Jeffrey W. Keillor
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12546 (2023)
Transglutaminase 2 (TG2) is a multifunctional enzyme primarily responsible for crosslinking proteins. Ubiquitously expressed in humans, TG2 can act either as a transamidase by crosslinking two substrates through formation of an Nε(ɣ-glutaminyl)lysi
Externí odkaz:
https://doaj.org/article/cc08aac5a3ef4e499a2f325c29def26c
Autor:
Emilie Marie Sophie Patit-Tha, Brun, Nicholas David, Calvert, Mojmír, Suchý, Alexia, Kirby, Gerd, Melkus, Ruslan, Garipov, Christina L, Addison, Adam J, Shuhendler
Publikováno v:
Chemical communications (Cambridge, England). 57(83)
A new CEST-MRI contrast agent, 2-HYNIC, capable of sensing aromatic aldehydes is reported. Pyridoxal 5'-phosphate, a key Vitamin B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7db0fa668bc0007e56fd9a23ea12b95b
https://pubmed.ncbi.nlm.nih.gov/34665184
https://pubmed.ncbi.nlm.nih.gov/34665184
Publikováno v:
Chemical communications (Cambridge, England). 55(37)
A new radiotracer, [
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::88aa22d4ab933b769a19653bde123164
https://pubmed.ncbi.nlm.nih.gov/30994648
https://pubmed.ncbi.nlm.nih.gov/30994648
Autor:
Gates, Eric W. J.1 (AUTHOR) egate028@uottawa.ca, Calvert, Nicholas D.1 (AUTHOR) ncalvert@uottawa.ca, Cundy, Nicholas J.1 (AUTHOR) n.cundy@hotmail.com, Brugnoli, Federica2 (AUTHOR) federica.brugnoli@unife.it, Navals, Pauline1 (AUTHOR) pnavals@uottawa.ca, Kirby, Alexia1 (AUTHOR) akirby@uottawa.ca, Bianchi, Nicoletta2 (AUTHOR) nicoletta.bianchi@unife.it, Adhikary, Gautam3 (AUTHOR) gadhikary@som.umaryland.edu, Shuhendler, Adam J.1 (AUTHOR) adam.shuhendler@uottawa.ca, Eckert, Richard L.3 (AUTHOR) reckert@som.umaryland.edu, Keillor, Jeffrey W.1 (AUTHOR) jkeillor@uottawa.ca
Publikováno v:
International Journal of Molecular Sciences. Aug2023, Vol. 24 Issue 16, p12546. 18p.
Autor:
Calvert, Nicholas D., Kirby, Alexia, Suchý, Mojmír, Pallister, Peter, Torrens, Aidan A., Burger, Dylan, Melkus, Gerd, Schieda, Nicola, Shuhendler, Adam J.
Publikováno v:
Nature Communications; 7/5/2023, Vol. 14 Issue 1, p1-13, 13p
Publikováno v:
Molecular Imaging & Biology; 2022 Suppl, Vol. 24, p63-480, 418p
Autor:
Cheng, Hang, Sebaa, Rajaa, Malholtra, Nikita, Lacoste, Baptiste, El Hankouri, Ziyad, Kirby, Alexia, Bennett, Nigel C., van Jaarsveld, Barry, Hart, Daniel W., Tattersall, Glenn J., Harper, Mary-Ellen, Pamenter, Matthew E.
Publikováno v:
Nature Communications; 11/23/2021, Vol. 12 Issue 1, p1-14, 14p