Zobrazeno 1 - 10
of 172
pro vyhledávání: '"Alexey. A. Nazarov"'
Autor:
Jana Kasparkova, Hana Kostrhunova, Vojtech Novohradsky, Аlexey A. Logvinov, Viktor V. Temnov, Nataliya E. Borisova, Tatiana A. Podrugina, Lenka Markova, Pavel Starha, Alexey. A. Nazarov, Viktor Brabec
Publikováno v:
Bioinorganic Chemistry and Applications, Vol 2022 (2022)
One concept of improving anticancer effects of conventional platinum-based antitumor drugs consists of conjugating these compounds with other biologically (antitumor) active agents, acting by a different mechanism. Here, we present synthesis, physico
Externí odkaz:
https://doaj.org/article/3ca46adcbf094b3faac19d8bb49e9a33
Publikováno v:
Naučno-tehničeskij Vestnik Informacionnyh Tehnologij, Mehaniki i Optiki, Vol 24, Iss 5, Pp 788-796 (2024)
Detection and handling of anomalous behavior in the network systems are peremptory efforts to ensure security for vulnerable infrastructures amidst the dynamic context of cybersecurity. In this paper, we propose an ensemble machine learning model a
Externí odkaz:
https://doaj.org/article/c806080dd3c24ed1b962e1ad42a779ff
Autor:
Ilya A. Shutkov, Nikolai A. Melnichuk, Konstantin A. Lyssenko, Nataliya E. Borisova, Olga N. Kovaleva, Alexey A. Nazarov
Publikováno v:
Molbank, Vol 2024, Iss 2, p M1816 (2024)
A metallacyclic maltol-tethered organometallic Ir(III) half-sandwich complex was synthesized as an analog of the ruthenium anticancer complexes (RAPTA/RAED) to evaluate its in vitro antiproliferative activity against various human cancer cell lines.
Externí odkaz:
https://doaj.org/article/3d5f2657080447e48dbc2b9a34bd47a5
Autor:
Anna A. Druzina, Nadezhda V. Dudarova, Ivan V. Ananyev, Anastasia A. Antonets, Dmitry N. Kaluzhny, Alexey A. Nazarov, Igor B. Sivaev, Vladimir I. Bregadze
Publikováno v:
Molecules, Vol 28, Iss 18, p 6636 (2023)
The synthesis of the first conjugates of acridine with cobalt bis(dicarbollide) are reported. A novel 9-azido derivative of acridine was prepared through the reaction of 9-methoxyacridine with N3CH2CH2NH2, and its solid-state molecular structure was
Externí odkaz:
https://doaj.org/article/22a168701c87409ea15358a4563480c9
Autor:
Anna S. Pavlova, Daniil A. Buslaev, Nataliya E. Borisova, Victor V. Temnov, Alexey A. Nazarov, Tatyana A. Podrugina
Publikováno v:
Molbank, Vol 2023, Iss 1, p M1564 (2023)
A huge variety of types of cancer makes it necessary to search for new effective drugs with a defined molecular target. Modification of substituents in ligands based on 3-hydroxy-1,1-cyclobutanedicarboxylic acid are one of the effective directions to
Externí odkaz:
https://doaj.org/article/346b1b4154bf480887bab1f4dd36c676
Publikováno v:
Molbank, Vol 2022, Iss 4, p M1506 (2022)
Bexarotene-tethered RuII(arene) compounds with 1,3,5-triaza-7-phosphatricyclo[3.3.1.1]decane (PTA) were prepared as an analog of RAPTA antitumor complexes in order to evaluate their in vitro antiproliferative activity against human cancer cell lines.
Externí odkaz:
https://doaj.org/article/7ba4cfd560c64085af87947b1e425622
Autor:
Ilya A. Shutkov, Yulia N. Okulova, Dmitrii M. Mazur, Nikolai A. Melnichuk, Denis A. Babkov, Elena V. Sokolova, Alexander A. Spasov, Elena R. Milaeva, Alexey A. Nazarov
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1366 (2023)
The combination of one molecule of organic and metal-based fragments that exhibit antitumor activity is a modern approach in the search for new promising drugs. In this work, biologically active ligands based on lonidamine (a selective inhibitor of a
Externí odkaz:
https://doaj.org/article/0bd7d89685c443d9b8dc0b254006d427
Autor:
Maria R. Gonchar, Fedor S. Ninin, Dmitrii M. Mazur, Konstantin A. Lyssenko, Elena R. Milaeva, Alexey A. Nazarov
Publikováno v:
Inorganics, Vol 11, Iss 3, p 124 (2023)
New organometallic iridium compounds with phosphorus modified glucose ligands containing isopropylidene protection group or bearing uracil, thymine, and 5-fluorouracil (3,5,6-bicyclophosphite-1,2-O-isopropylidene-α-d-glucofuranoside, 3,5,6-bicycloph
Externí odkaz:
https://doaj.org/article/6162294b2fee4594b941b1f71dc1a26d
Autor:
Alexey N. Nazarov
Publikováno v:
Российский технологический журнал, Vol 7, Iss 6, Pp 56-67 (2020)
The creation of monitoring clusters based on cloud computing technologies is a promising direction for the development of systems for continuous monitoring of objects for various purposes in the web space. Hadoop web-programming environment is the te
Externí odkaz:
https://doaj.org/article/06a1c730511249a6b4b606c2ca1a6ee6
Publikováno v:
Lifelong Education: the XXI century. 41:14-33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d8aec400e8dec1abe28236138fdc2ed
https://doi.org/10.15393/j5.art.2023.8245
https://doi.org/10.15393/j5.art.2023.8245