Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Alexey V. Tkach"'
Autor:
Dmitriy W. Gutkin, Galina V. Shurin, Naveena Yanamala, Alexander Star, Anna A. Shvedova, Elena R. Kisin, Alexey V. Tkach, Michael R. Shurin, Valerian E. Kagan
Publikováno v:
Cancer Research. 75:1615-1623
During the last decades, changes have been observed in the frequency of different histologic subtypes of lung cancer, one of the most common causes of morbidity and mortality, with a declining proportion of squamous cell carcinomas and an increasing
Autor:
Bengt Fadeel, Howard D. Leonard, Ashley R. Murray, Jeffrey S. Reynolds, Naveena Yanamala, Kai Savolainen, Valerian E. Kagan, Alexey V. Tkach, Michael R. Shurin, Alexander Star, Galina V. Shurin, Dmirtiy W. Gutkin, Elena R. Kisin, Anna A. Shvedova
Publikováno v:
ACS Nano
Several lines of evidence indicate that exposure to nanoparticles (NPs) is able to modify airway immune responses, thus facilitating the development of respiratory diseases. Graphene oxide (GO) is a promising carbonaceous nanomaterial with unique phy
Autor:
Phouthone Keohavong, Vincent Castranova, Ann F. Hubbs, Madalina M. Chirila, Sycheva Lp, Elena R. Kisin, Ashley R. Murray, Naveena Yanamala, Anna A. Shvedova, Valerian E. Kagan, Alexey V. Tkach
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 306:L170-L182
The hallmark geometric feature of single-walled carbon nanotubes (SWCNT) and carbon nanofibers (CNF), high length to width ratio, makes them similar to a hazardous agent, asbestos. Very limited data are available concerning long-term effects of pulmo
Autor:
Naveena Yanamala, Meghan K. Hatfield, Q. T. Krantz, Charly King, Alexey V. Tkach, M. Ian Gilmour, Ashley R. Murray, Stephen H. Gavett, David Nash, Elena R. Kisin, Timur O. Khaliullin, Anna A. Shvedova
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 76:907-921
Over the past decade, soy biodiesel (BD) has become a first alternative energy source that is economically viable and meets requirements of the Clean Air Act. Due to lower mass emissions and reduced hazardous compounds compared to diesel combustion e
Autor:
Shayla Stanley, Valerian E. Kagan, Timur O. Khaliullin, Yanan Chen, Galina V. Shurin, Anna A. Shvedova, Michael R. Shurin, Dmitriy W. Gutkin, Elena R. Kisin, Alexander Star, Alexey V. Tkach
Publikováno v:
Small. 9:1691-1695
Metastatic establishment and growth of Lewis lung carcinoma is promoted by single-walled carbon nanotubes (SWCNT) in C57BL6/J mice. The effect is mediated by increased local and systemic accumulation of myeloid-derived suppressor cells (MDSC), as the
Autor:
Bengt Fadeel, Terrance Burks, Micah Waltz, Alfred O. Inman, Vincent Castranova, Valerian E. Kagan, Elena R. Kisin, Jim E. Riviere, Ashley R. Murray, Abdusalam Uheida, Shih-Houng Young, Anna A. Shvedova, Mamoun Muhammed, Alexey V. Tkach, Nancy A. Monteiro-Riviere
Publikováno v:
Cell Biochemistry and Biophysics. 67:461-476
A number of commercially available metal/metal oxide nanoparticles (NPs) such as superparamagnetic iron oxide (SPION) are utilized by the medical field for a wide variety of applications. These NPs may able to induce dermal toxicity via their physica
Autor:
Ashley R. Murray, Alexey V. Tkach, Anna A. Shvedova, Alexander Star, Valerian E. Kagan, Michael R. Shurin, Shih-Houng Young, Elena R. Kisin, Bengt Fadeel, Galina V. Shurin
Publikováno v:
ACS Nano. 5:5755-5762
Pharyngeal aspiration of single-walled carbon nanotubes (SWCNTs) caused inflammation, pulmonary damage, and an altered cytokine network in the lung. Local inflammatory response in vivo was accompanied by modified systemic immunity as documented by de
Autor:
Shyla Stanley, Shengli Gao, Elena R. Kisin, Valerian E. Kagan, Michael R. Shurin, Alexey V. Tkach, Y. Peter Di, Naveena Yanamala, Anna A. Shvedova
Publikováno v:
American journal of respiratory cell and molecular biology. 49(5)
Carbon nanotubes (CNTs; allotropes of carbon with a cylindrical nanostructure) have emerged as one of the most commonly used types of nanomaterials, with numerous applications in industry and biomedicine. However, the inhalation of CNTs has been show
Autor:
Gregg P. Kotchey, Sanjay Mathur, Vincent Castranova, Alexey V. Tkach, Naveena Yanamala, Shyla Stanley, Ashley R. Murray, Valerian E. Kagan, Elena R. Kisin, Bengt Fadeel, Samantha Pareso, Alexander Star, Galina V. Shurin, Anna A. Shvedova, Michael R. Shurin, Timur O. Khaliullin
Publikováno v:
Small (Weinheim an der Bergstrasse, Germany). 9(9-10)
Graphene oxide (GO) and C60 - or C60 -TRIS fullerenes, internalized by murine dendritic cells (DCs), differently affect their abilities to present antigens to T-cells. While C60 -fullerenes stimulate the ovalbumin-specific MHC class I-restricted T-ce
Autor:
Alexey V. Tkach, Ashley R. Murray, Anna A. Shvedova, Bengt Fadeel, Susanna Kumlien Georén, Annika Scheynius, Britta Andersson-Willman, Mikael C. I. Karlsson, Yunying Chen, Antonio Barragan, Romanico B. G. Arrighi, Linda Swedin
Publikováno v:
Particle and Fibre Toxicology
Particle and Fibre Toxicology, Vol 9, Iss 1, p 16 (2012)
Particle and Fibre Toxicology, Vol 9, Iss 1, p 16 (2012)
Background Single-walled carbon nanotubes (SWCNT) trigger pronounced inflammation and fibrosis in the lungs of mice following administration via pharyngeal aspiration or inhalation. Human exposure to SWCNT in an occupational setting may occur in conj