Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Alexey V. Morozov"'
Autor:
Vladimir A. Morozov, Alexey V. Morozov
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12398 (2021)
About 8% of our genome is composed of sequences from Human Endogenous Retroviruses (HERVs). The HERV-K (HML.2) family, here abbreviated HML.2, is able to produce virus particles that were detected in cell lines, malignant tumors and in autoimmune dis
Externí odkaz:
https://doaj.org/article/cb2f380eb61c4257bcb168b58714d47b
Autor:
Alexey V. Morozov, Vadim L. Karpov
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
The life of every organism is dependent on the fine-tuned mechanisms of protein synthesis and breakdown. The degradation of most intracellular proteins is performed by the ubiquitin proteasome system (UPS). Proteasomes are central elements of the UPS
Externí odkaz:
https://doaj.org/article/911665e69f6c40739a5af6841efb8f5f
Autor:
Alexey V. Morozov, Vadim L. Karpov
Publikováno v:
Heliyon, Vol 4, Iss 10, Pp e00894- (2018)
Cell homeostasis and regulation of metabolic pathways are ensured by synthesis, proper folding and efficient degradation of a vast amount of proteins. Ubiquitin-proteasome system (UPS) degrades most intracellular proteins and thus, participates in re
Externí odkaz:
https://doaj.org/article/eb8aa340f83d4a31b72a39558de0a91a
Autor:
Tatiana M. Astakhova, Alexey V. Morozov, Pavel A. Erokhov, Maria I. Mikhailovskaya, Sergey B. Akopov, Natalia I. Chupikova, Ruslan R. Safarov, Natalia P. Sharova
Publikováno v:
Cancers, Vol 10, Iss 10, p 351 (2018)
Tumor growth is associated with elevated proteasome expression and activity. This makes proteasomes a promising target for antitumor drugs. Current antitumor drugs such as bortezomib that inhibit proteasome activity have significant side effects. The
Externí odkaz:
https://doaj.org/article/f1b7de935cfe4e7e8f22373d2bb0b338
Publikováno v:
The Bulletin of Contemporary Clinical Medicine. 14:117-123
Aim. The article considers materials that allow evaluating the way of establishment of medical service for customs authorities during the XIX–XX centuries. Material and methods. The study was conducted in a combination of the main methodological pr
Publikováno v:
Hygiene and sanitation. 100:178-181
The article is devoted to I.V. Bertenson, the famous Russian hygienist and public figure, organizer of health care, a staunch follower of N.I. Pirogov. I.V. Bertenson made a significant contribution to the development of hospital hygiene in Russia. H
Publikováno v:
Programming and Computer Software. 46:384-396
The problem of lazy visualization of ontological graphs has certain constraints. Visualization of structures that contain blank nodes is especially challenging. In this paper, we propose an approach to visualization of these structures that is implem
Autor:
Timofey D. Lebedev, Elmira R. Khabusheva, Sofia R. Mareeva, Karina A. Ivanenko, Alexey V. Morozov, Pavel V. Spirin, Petr M. Rubtsov, Anastasiya V. Snezhkina, Anna V. Kudryavtseva, Maxim I. Sorokin, Anton A. Buzdin, Vladimir S. Prassolov
Publikováno v:
The Journal of biological chemistry. 298(8)
Increased MAPK signaling is a hallmark of various cancers and is a central regulator of cell survival. Direct ERK1/2 inhibition is considered a promising approach to avoid ERK1/2 reactivation caused by upstream kinases BRAF, MEK1/2, and KRAS, as well
Autor:
Alexey V. Morozov, Irina V. Egorysheva
Publikováno v:
The Bulletin of Contemporary Clinical Medicine. 13:70-75
Publikováno v:
Physical Review B. 103
We analyze the valley selection rules for optical transitions from impurity states to the conduction band in two-dimensional Dirac materials, taking a monolayer of MoS2 as an example. We employ the analytical model of a shallow impurity potential whi