Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Alexey V. Kuzikov"'
Autor:
Alexey V. Kuzikov, Rami A. Masamrekh, Tatiana A. Filippova, Anastasiya M. Tumilovich, Natallia V. Strushkevich, Andrei A. Gilep, Yulia Yu. Khudoklinova, Victoria V. Shumyantseva
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 152 (2024)
We describe a bielectrode system for evaluation of the electrocatalytic activity of cytochrome P450 2E1 (CYP2E1) towards chlorzoxazone. One electrode of the system was employed to immobilize Bactosomes with human CYP2E1, cytochrome P450 reductase (CP
Externí odkaz:
https://doaj.org/article/9be09772c041412986e3ecb53905337b
Publikováno v:
Electrocatalysis. 13:630-640
Publikováno v:
Biophysical chemistry. 291
The possibility of the detection of atypical kinetic profiles of drug biotransformation using electrochemical systems based on immobilized cytochromes P450 with phenytoin hydroxylation by cytochrome P450 2C19 (CYP2C19) as an example was evaluated for
Autor:
Tatiana A. Filippova, Rami A. Masamrekh, Victoria V. Shumyantseva, Ivan A. Latsis, Tatiana E. Farafonova, Irina Y. Ilina, Sergey L. Kanashenko, Sergei A. Moshkovskii, Alexey V. Kuzikov
Publikováno v:
Talanta. 257:124341
Autor:
Rami A. Masamrekh, Alexey V. Kuzikov, Dmitry V. Pergushov, Tatiana V. Bulko, Lubov E Agafonova, Larisa V. Sigolaeva, Victoria V. Shumyantseva, Jiayin Yuan
Publikováno v:
Biochemistry (Moscow). 86:S140-S151
Methods of electrochemical analysis of biological objects based on the reaction of electro-oxidation/electro-reduction of molecules are presented. Polymer nanocomposite materials that modify electrodes to increase sensitivity of electrochemical event
Autor:
Rami A. Masamrekh, A. A. Makhova, S. M. Rikova, T. V. Bulko, Victoria V. Shumyantseva, Andrey Gilep, P. I. Koroleva, D. A. Filimonov, Alexey V. Kuzikov, E. V. Shich, Alexander V. Dmitriev, M. G. Zaviyalova
Publikováno v:
Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry. 15:62-70
In the present study an electrochemical system based on recombinant cytochrome P450 3A4 (CYP3A4) has been developed for analysis of potential drug-drug interactions between drugs prescribed for Helicobacter pylori eradication therapy. The drug-drug i
Autor:
Victoria V. Shumyantseva, P. I. Koroleva, Rami A. Masamrekh, Andrey Gilep, Alexey V. Kuzikov, T. V. Bulko, S. S. Babkina
Publikováno v:
Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry. 14:252-259
The electroanalytical characteristics of the recombinant cytochrome P450 3A4 (CYP3A4) immobilized on the surface of screen-printed graphite electrodes modified by multi-walled carbon nanotubes (MWCNTs) have been investigated. The role and the influen
Autor:
Victoria V. Shumyantseva, Rami A. Masamrekh, Andrew Ivanov, Alexey V. Kuzikov, Sergey A. Usanov, Yuri Mezentsev, P V Ershov, Andrei A. Gilep
Publikováno v:
BioNanoScience. 10:157-167
In the present study, the effects of endogenous non-peptide bioregulator isatin (indole-2,3-dione) cytochrome P450 isoenzymes 3A5, 3A4, 2C19, 2E1, and 5A1 were investigated for the first time by means of electrochemical methods. Absorption spectrosco
Autor:
Elizaveta M. Solovyeva, Ksenia G. Kuznetsova, Mikhail V. Gorshkov, Sergei A. Moshkovskii, Alexey V. Kuzikov
Publikováno v:
Europe PubMed Central
Mass spectrometric proteomic analysis at the sample preparation stage involves the artificial reduction of disulfide bonds in proteins formed between cysteine residues. Such bonds, when preserved in their native state, complicate subsequent enzymatic
Autor:
Victoria V. Shumyantseva, S. S. Babkina, Andrey Gilep, Rami A. Masamrekh, Alexey V. Kuzikov, P. I. Koroleva, T. V. Bulko
Publikováno v:
Biomeditsinskaya Khimiya. 66:64-70
The electroanalytical characteristics of recombinant cytochrome P450 3A4 (P450 3A4) immobilized on the surface of screen-printed graphite electrodes modified with multi-walled carbon nanotubes have been studied. The role and the influence of graphite