Zobrazeno 1 - 10 of 19 pro vyhledávání: '"Alexey V. Finkelstein"'
1
How to Determine the Size of Folding Nuclei of Protofibrils from the Concentration Dependence of the Rate and Lag-Time of Aggregation. I. Modeling the Amyloid Protofibril Formation
Autor: Alexey V. Finkelstein, Oxana V. Galzitskaya, Nikita V. Dovidchenko
Publikováno v: The Journal of Physical Chemistry B. 118:1189-1197
The question about the size of nuclei of formation of protofibrils (which constitute mature amyloid fibrils) formed by different proteins and peptides is yet open and debatable because of the absence of solid knowledge of underlying mechanisms of amy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6379cb86ae3d05a500416872239526f3
https://doi.org/10.1021/jp4083294
Zobrazit plný text záznamu
2
Cunning Simplicity of a Stoichiometry Driven Protein Folding Thesis
Autor: Alexey V. Finkelstein, Michael Yu Lobanov, Oxana V. Galzitskaya
Publikováno v: Journal of Biomolecular Structure and Dynamics. 28:595-598
present two statements, which, as they say, ‘reveal a surprisingly sim-ple unifying principle of backbone organization in protein folding’ (1). Namely, they assert (i) ‘that protein folding is a direct consequence of a narrow band of stoichiome
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d8ab06f6d7b0bdfd2da1173a2c4582e4
https://doi.org/10.1080/073911011010524958
Zobrazit plný text záznamu
3
Determination of the Size of the Primary and Secondary Folding Nuclei of Protofibrils from the Concentration Dependence of the Rate and the Lag-Time of Their Formation
Autor: Maria Yu. Suvorina, Alexey V. Finkelstein, Oxana V. Galzitskaya, Olga M. Selivanova, Alexey K. Surin, Nikita V. Dovidchenko
Publikováno v: Physical Biology of Proteins and Peptides ISBN: 9783319216867
A kinetic model of the process of formation of amyloid protofibrils is proposed, allowing calculation of the nucleus size solely from kinetic data. This model includes the primary nucleation, the linear growth of protofibrils binding monomers to thei
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ac5cc1aac135563a9fbe9cc3e17d7bef
https://doi.org/10.1007/978-3-319-21687-4_3
Zobrazit plný text záznamu
4
Statistical significance of protein structure prediction by threading
Autor: Alexey V. Finkelstein, Eugene I. Shakhnovich, Leonid A. Mirny
Publikováno v: Proceedings of the National Academy of Sciences. 97:9978-9983
In this study, we estimate the statistical significance of structure prediction by threading. We introduce a single parameter ɛ that serves as a universal measure determining the probability that the best alignment is indeed a native-like analog. Pa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c79e496283b126fe9d3c5187a885c7c
https://doi.org/10.1073/pnas.160271197
Zobrazit plný text záznamu
6
S6 permutein shows that the unusual target topology is not responsible for the absence of rigid tertiary structure in de novo protein albebetin
Autor: Vladimir N. Uversky, Dmitry A. Dolgikh, Azat Ya. Badretdinov, Alexey V. Finkelstein, Mikhail P. Kirpichnikov, Ziedulla Kh. Abdullaev, Ramil F. Latypov
Publikováno v: FEBS Letters. 414:243-246
Ribosomal protein S6 from Thermus thermophilus was modified to form the unusual unique topology designed earlier for a de novo protein albebetin. The S6 gene was cloned, sequenced and circularly permutated by means of genetic engineering methods. The
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c96128f1ff503664c0ae85b43a7c83bb
https://doi.org/10.1016/s0014-5793(97)01042-9
Zobrazit plný text záznamu
7
Development and testing of PFFSol1.1, a new polarizable atomic force field for calculation of molecular interactions in implicit water environment
Autor: Leonid B. Pereyaslavets, Alexey V. Finkelstein
Publikováno v: The journal of physical chemistry. B. 116(15)
A detailed calculation of protein interactions with explicitly considered water molecules takes enormous time. If water is considered implicitly (as media rather than as molecules), calculations become faster. These calculations are less precise, unl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b9a3de0f7b5199785fbe97ce90325d8
https://pubmed.ncbi.nlm.nih.gov/22439906
Zobrazit plný text záznamu
8
A new approach to artificial and modified proteins: theory-based design, synthesis in a cell-free system and fast testing of structural properties by radiolabels
Autor: V.V. Chemeris, Ptitsyn Ob, Kirpichnikov Mp, Alexey V. Finkelstein, Dmitry A. Dolgikh, A. N. Fedorov, Vladimir N. Uversky
Publikováno v: "Protein Engineering, Design and Selection". 7:1041-1052
A novel approach to the creation of artificial and modified proteins has been elaborated. The approach includes a sequence design based on the molecular theory of protein secondary structure and folding patterns, gene expression in a cell-free system
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212312fb34cd00d752605850a5fb9e7e
https://doi.org/10.1093/protein/7.8.1041
Zobrazit plný text záznamu
10
Accurate general method for lattice approximation of three-dimensional structure of a chain molecule
Autor: Alexey V. Finkelstein, Dmitry S. Rykunov, Boris A. Reva
Publikováno v: Proteins. 22(2)
An algorithm based on dynamic programming gives the lattice models having the minimal RMS deviations from the actual folds of protein (RNA, etc.) chains for a given lattice and a given orientation of the macromolecule relative to the lattice. The alg
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3060d45b42833a1452a8fc400d1408a5
https://pubmed.ncbi.nlm.nih.gov/7567958
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje