Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Alexey V Zaitsev"'
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212076 (2019)
While an ischemic insult poses a lethal danger to myocardial cells, a significant proportion of cardiac myocytes remain viable throughout the ischemic episode and die, paradoxically, only after the blood flow is reinstated. Despite decades of researc
Externí odkaz:
https://doaj.org/article/cfe7e22b53f24f7890142714e8e0a66e
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200301 (2018)
A prominent theory of cell death in myocardial ischemia/reperfusion (I/R) posits that the primary and pivotal step of irreversible cell injury is the opening of the mitochondrial permeability transition (MPT) pore. However, the predominantly positive
Externí odkaz:
https://doaj.org/article/07ab90e62eb14a90bd943f7ff218cdc7
Autor:
Denis V Dedkov, Alexey V Zaitsev
Publikováno v:
Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, Vol 17, Iss 4, Pp 66-75 (2013)
A new model has been developed to simulate a woven textile composite layer with a polycrystalline matrix. Based on the numerical solution of the boundary-value problem by the finite-element method, the values of stress concentration caused by local
Externí odkaz:
https://doaj.org/article/9831a3d68bbb4e01b473d450ac9ead6c
Autor:
Alexey V Zaitsev, Anton A Fukalov
Publikováno v:
Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, Vol 14, Iss 2, Pp 85-95 (2010)
Using decomposition of hoop and radial components of displacement vector to the trigonometrical and generalized power series, the new precise analytical solution to problem on equilibrium state of thick-walled heavy transversally-isotropic central-sy
Externí odkaz:
https://doaj.org/article/b52d16f2499540dd88f0085033db6c31
Autor:
Junko Shibayama, Tatiana N Yuzyuk, James Cox, Aman Makaju, Mickey Miller, Justin Lichter, Hui Li, Jane D Leavy, Sarah Franklin, Alexey V Zaitsev
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118974 (2015)
Heart failure (HF) is accompanied by complex alterations in myocardial energy metabolism. Up to 40% of HF patients have dyssynchronous ventricular contraction, which is an independent indicator of mortality. We hypothesized that electromechanical dys
Externí odkaz:
https://doaj.org/article/6f3ad693d0754bbb9dec7dd1d18dc9c1
Autor:
Junko Shibayama, Tyson G Taylor, Paul W Venable, Nathaniel L Rhodes, Ryan B Gil, Mark Warren, Adam R Wende, E Dale Abel, James Cox, Kenneth W Spitzer, Alexey V Zaitsev
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57821 (2013)
Deterioration of ventricular fibrillation (VF) into asystole or severe bradycardia (electrical failure) heralds a fatal outcome of cardiac arrest. The role of metabolism in the timing of electrical failure remains unknown.To determine metabolic facto
Externí odkaz:
https://doaj.org/article/335b73c3d45445abbb170660e8ff5735
Autor:
Ivan A. Panteleev, Alexey V. Zaitsev, Konstantin B. Ustinov, Virginia A. Mubassarova, Nikolai I. Shevtsov, Valerii V. Khimulia, Vladimir I. Karev, Yurii F. Kovalenko
Publikováno v:
Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, Vol 26, Iss 2, Pp 293-310 (2022)
The paper describes the mechanisms and conditions for the damage-memory effect (Kaiser effect) in rocks subjected to a three-dimensional nonproportional cyclic loading with changes in the rocks' shape and orientation of the Lam-ellipsoid. The experim
Externí odkaz:
https://doaj.org/article/047e4d6690834af18364e8af6387c033
Publikováno v:
Studies in Systems, Decision and Control ISBN: 9783030564322
The aim of this work was the need to show that robotics and artificial intelligence in the modern economy have become not only its integral part, but, without exaggeration, its very foundation. In our world of high speeds and lack of time, the need f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b1cc7a82d00ca547ab552aa9b9f50a9
https://doi.org/10.1007/978-3-030-56433-9_23
https://doi.org/10.1007/978-3-030-56433-9_23
Autor:
Alexey V. Zaitsev, Mark Warren
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Frontiers in Physiology
Frontiers in Physiology
The traditional view of ventricular excitation and conduction is an all-or-nothing response mediated by a regenerative activation of the inward sodium channel, which gives rise to an essentially constant conduction velocity (CV). However, whereas the
Autor:
David A. Nix, Amanda Horiuchi, Katie J. Sciuto, Yukio Saijoh, Alexey V. Zaitsev, Junco S. Warren, Chris Stubborn, Keiko M. Cawley, Amira D. Sabry
Publikováno v:
Circulation Research. 125
Our recent study demonstrated that the histone methyltransferase Smyd1 positively regulates cardiac metabolism through transcriptional control of PGC-1α, a key regulator of mitochondrial energetics. However, it is largely unknown whether Smyd1 plays