Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Alexey V Deykin"'
Autor:
Olesya A Puchenkova, Vladislav O Soldatov, Andrei E Belykh, OlgaYu Bushueva, Gennadii A Piavchenko, Artem A Venediktov, Nikolay K Shakhpazyan, Alexey V Deykin, Mikhail V Korokin, Mikhail V Pokrovskiy
Publikováno v:
Biomarker Insights, Vol 17 (2022)
Abdominal aortic aneurysm (AAA) is a potentially life-threatening disorder with a mostly asymptomatic course where the abdominal aorta is weakened and bulged. Cytokines play especially important roles (both positive and negative) among the molecular
Externí odkaz:
https://doaj.org/article/cec076cfd1fc4365a922c36d1b28a828
Autor:
Tatiana V. Egorova, Anna V. Polikarpova, Svetlana G. Vassilieva, Marina A. Dzhenkova, Irina M. Savchenko, Oleg A. Velyaev, Anna A. Shmidt, Vladislav O. Soldatov, Mikhail V. Pokrovskii, Alexey V. Deykin, Maryana V. Bardina
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 30, Iss , Pp 161-180 (2023)
Duchenne muscular dystrophy (DMD) is a severe hereditary disease caused by a deficiency in the dystrophin protein. The most frequent types of disease-causing mutations in the DMD gene are frameshift deletions of one or more exons. Precision genome ed
Externí odkaz:
https://doaj.org/article/86a0dbc1beb14091855dc8b5f24c41bb
Autor:
Andrei E. Belykh, Vladislav O. Soldatov, Tatiana A. Stetskaya, Ksenia A. Kobzeva, Maria O. Soldatova, Alexey V. Polonikov, Alexey V. Deykin, Mikhail I. Churnosov, Maxim B. Freidin, Olga Y. Bushueva, Dr.
Publikováno v:
IBRO Neuroscience Reports, Vol 14, Iss , Pp 453-461 (2023)
Background: Ischemic stroke (IS) is one of the most serious cardiovascular events associated with high risk of death or disability. The growing body of evidence highlights molecular chaperones as especially important players in the pathogenesis of th
Externí odkaz:
https://doaj.org/article/6b944a4a05384e77a165ff68452d9a39
Autor:
Anna V. Polikarpova, Tatiana V. Egorova, Evgenii A. Lunev, Alexandra A. Tsitrina, Svetlana G. Vassilieva, Irina M. Savchenko, Yuliya Y. Silaeva, Alexey V. Deykin, Maryana V. Bardina
Publikováno v:
Frontiers in Genome Editing, Vol 5 (2023)
The development of personalized medicine for genetic diseases requires preclinical testing in the appropriate animal models. GNAO1 encephalopathy is a severe neurodevelopmental disorder caused by heterozygous de novo mutations in the GNAO1 gene. GNAO
Externí odkaz:
https://doaj.org/article/23346d150ced45478ada50824f70075c
Autor:
Vladislav O. Soldatov, Marina V. Kubekina, Marina Yu. Skorkina, Andrei E. Belykh, Tatiana V. Egorova, Mikhail V. Korokin, Mikhail V. Pokrovskiy, Alexey V. Deykin, Plamena R. Angelova
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/a0a2d8ffccbb49c1b13c8a911815d4b1
Autor:
Andrey Y. Vinokurov, Vladislav O. Soldatov, Evgenia S. Seregina, Angelina I. Dolgikh, Pavel A. Tagunov, Andrey V. Dunaev, Marina Y. Skorkina, Alexey V. Deykin, Andrey Y. Abramov
Publikováno v:
Molecular Neurobiology. 60:3147-3157
Alterations in function of hypoxanthine guanine phosphoribosyl transferase (HPRT), one of the major enzymes involved in purine nucleotide exchange, lead to overproduction of uric acid and produce various symptoms of Lesch-Nyhan syndrome (LNS). One of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8251cda74fcd7e785768b5627082a1e7
https://doi.org/10.1007/s12035-023-03266-2
https://doi.org/10.1007/s12035-023-03266-2
Autor:
Anna S. Krivonogova, Alexandra V. Bruter, Valeria A. Makutina, Yuliya D. Okulova, Leonid A. Ilchuk, Marina V. Kubekina, Alexandra Yu Khamatova, Tatiana V. Egorova, Vladimir S. Mymrin, Yuliya Yu Silaeva, Alexey V. Deykin, Maxim A. Filatov, Albina G. Isaeva
Publikováno v:
Theriogenology. 193:77-86
Adeno-associated viruses (AAV) are widely used in the field of genetically modified organism production. In this work, transduction of bovine embryos by AAV was selected as a potential approach to perform genetic modifications: we have used recombina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::093275edce42ef47abc1be28086a5fd2
https://doi.org/10.1016/j.theriogenology.2022.09.007
https://doi.org/10.1016/j.theriogenology.2022.09.007
Autor:
Indira S. Kochkarova, Viktor V. Vasyutkin, Alexandra I. Radchenko, Olesya V. Shcheblykina, Julia V. Stepenko, Vladimir I. Yakushev, Alexey V. Deykin, Elena V. Kuzubova, Olesya A. Vanchenko, Vladimir M. Pokrovsky, Elena E. Povetka, Polina A. Golubinskaya, Konstantin S. Trunov, Anton P. Danilenko, Liliya V. Korokina, Veronika S. Belyaeva
Publikováno v:
Research Results in Pharmacology, Vol 7, Iss 4, Pp 11-27 (2021)
Introduction: In this review, the analysis of technologies for obtaining biologically active proteins from various sources is carried out, and the comparative analysis of technologies for creating producers of biologically active proteins is presente
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2f39d5c24a23ba110c91d72209a718d
https://rrpharmacology.pensoft.net/article/76685/
https://rrpharmacology.pensoft.net/article/76685/
Autor:
Vladislav O. Soldatov, Marina V. Kubekina, Marina Yu. Skorkina, Andrei E. Belykh, Tatiana V. Egorova, Mikhail V. Korokin, Mikhail V. Pokrovskiy, Alexey V. Deykin, Plamena R. Angelova
Publikováno v:
Journal of Translational Medicine. 20
Mitochondrial diseases (MD) are a heterogeneous group of multisystem disorders involving metabolic errors. MD are characterized by extremely heterogeneous symptoms, ranging from organ-specific to multisystem dysfunction with different clinical course
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edf040365c86c7915937e43d0ca02a51
https://doi.org/10.1186/s12967-022-03685-0
https://doi.org/10.1186/s12967-022-03685-0
Autor:
Alexandra V. Bruter, Yulia D. Okulova, Diana S. Korshunova, M. V. Korokin, Yulia Yu. Silaeva, Inga M. Kolesnik, Leonid A. Ilchuk, Mariya O. Soldatova, Marina V. Kubekina, Polina A. Ukolova, Alexey V. Deykin, Evgeniya Seryogina
Publikováno v:
Research Results in Pharmacology, Vol 7, Iss 3, Pp 33-39 (2021)
Research Results in Pharmacology 7(3): 33-39
Research Results in Pharmacology 7(3): 33-39
Introduction: PolG-alpha is a nuclear-encoded enzyme which provides replication and repair of mitochondrial DNA. D257A mutation of PolG-alpha leads to change in the N-terminal ”proofreading” domain, which deprives the enzyme of 3′-5′ exonucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9ac6aa0fd1c16c1c5f4d0855aff55b5
https://doi.org/10.3897/rrpharmacology.7.72784
https://doi.org/10.3897/rrpharmacology.7.72784