Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Alexey S Revenko"'
Autor:
Yi Li, Jose L. Mondaza-Hernandez, David S. Moura, Alexey S. Revenko, Angelica Tolentino, John T. Nguyen, Nam Tran, Clark A. Meyer, Jose Merino-Garcia, Rafael Ramos, Davide Di Lernia, Javier Martin-Broto, Heather N. Hayenga, Leonidas Bleris
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 2, Pp 102154- (2024)
Solitary fibrous tumor (SFT) is a rare, non-hereditary soft tissue sarcoma thought to originate from fibroblastic mesenchymal stem cells. The etiology of SFT is thought to be due to an environmental intrachromosomal gene fusion between NGFI-A-binding
Externí odkaz:
https://doaj.org/article/5d8f5d5b1be74d249583ba786160cba2
Autor:
Nayela N. Chowdhury, Yi Yang, Ananya Dutta, Michelle Luo, Zimu Wei, Sara R. Abrahams, Alexey S. Revenko, Fenil Shah, Lindsey A. Miles, Robert J. Parmer, Bas deLaat, Alisa S. Wolberg, James P. Luyendyk, Melissa L. Fishel, Matthew J. Flick
Publikováno v:
Molecular Oncology, Vol 18, Iss 1, Pp 113-135 (2024)
Pancreatic ductal adenocarcinoma (PDAC) is a highly fatal metastatic disease associated with robust activation of the coagulation and fibrinolytic systems. However, the potential contribution of the primary fibrinolytic protease plasminogen to PDAC d
Externí odkaz:
https://doaj.org/article/d7e6f70905c245e1a019d7d8c2f2e56f
Autor:
Edward J. Sanderlin, Melissa M. Keenan, Martin Mense, Alexey S. Revenko, Brett P. Monia, Shuling Guo, Lulu Huang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Currently, there is no therapy for patients with cystic fibrosis caused by nonsense mutations. Here the authors show that CFTR mRNAs with nonsense codons are predominantly degraded by the SMG6-mediated branch of the NMD pathway, providing potential t
Externí odkaz:
https://doaj.org/article/0bd6da00b0e3497583db276b1d3e35c5
Autor:
Toshiaki Shirai, Alexey S. Revenko, Justin Tibbitts, Anh T.P. Ngo, Annachiara Mitrugno, Laura D. Healy, Jennifer Johnson, Erik I. Tucker, Monica T. Hinds, Lisa M. Coussens, Owen J.T. McCarty, Brett P. Monia, András Gruber
Publikováno v:
Blood Advances, Vol 3, Iss 20, Pp 3080-3091 (2019)
Abstract: In humans, platelet count within the normal range is required for physiological hemostasis, but, adversely, platelets also support pathological thrombosis. Moreover, by releasing growth factors, they may enhance neoplastic proliferation. We
Externí odkaz:
https://doaj.org/article/4c4e4254f9bf4a1ba88e8704d6fc1b2e
Autor:
Brendan T Finicle, Kazumi H Eckenstein, Alexey S Revenko, Brooke A Anderson, W Brad Wan, Alison N McCracken, Daniel Gil, David A Fruman, Stephen Hanessian, Punit P Seth, Aimee L Edinger
Publikováno v:
Nucleic Acids Research. 51:1583-1599
Inefficient endosomal escape remains the primary barrier to the broad application of oligonucleotide therapeutics. Liver uptake after systemic administration is sufficiently robust that a therapeutic effect can be achieved but targeting extrahepatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fde1b5fd23940ce7c0ce0235ad04603
https://doi.org/10.1093/nar/gkad023
https://doi.org/10.1093/nar/gkad023
Autor:
Kewen He, Hampartsoum B. Barsoumian, Nahum Puebla-Osorio, Yun Hu, Duygu Sezen, Mark D. Wasley, Genevieve Bertolet, Jie Zhang, Carola Leuschner, Liangpeng Yang, Claudia S. Kettlun Leyton, Natalie Wall Fowlkes, Morgan Maureen Green, Lisa Hettrick, Dawei Chen, Fatemeh Masrorpour, Meidi Gu, Hadi Maazi, Alexey S. Revenko, Maria Angelica Cortez, James W. Welsh
Publikováno v:
Cancer Immunology Research. 11:486-500
Diverse factors contribute to the limited clinical response to radiotherapy (RT) and immunotherapy in metastatic non–small cell lung cancer (NSCLC), among which is the ability of these tumors to recruit a retinue of suppressive immune cells—such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eae04614541ce88205150bb063becca8
https://doi.org/10.1158/2326-6066.cir-22-0547
https://doi.org/10.1158/2326-6066.cir-22-0547
Autor:
Juliane Köhler, Claudia Maletzki, Dirk Koczan, Marcus Frank, Armin Springer, Carolin Steffen, Alexey S. Revenko, A.Robert MacLeod, Stefan Mikkat, Bernd Kreikemeyer, Sonja Oehmcke-Hecht
Publikováno v:
EBioMedicine, Vol 58, Iss , Pp 102908- (2020)
Background: High-molecular-weight kininogen is a cofactor of the human contact system, an inflammatory response mechanism that is activated during sepsis. It has been shown that high-molecular-weight kininogen contributes to endotoxemia, but is not c
Externí odkaz:
https://doaj.org/article/03c0be58cc2b4ae5b6157e4c68ca453c
Autor:
Juliane Köhler, Claudia Maletzki, Dirk Koczan, Marcus Frank, Carolin Trepesch, Alexey S. Revenko, Jeffrey R. Crosby, A. Robert Macleod, Stefan Mikkat, Sonja Oehmcke-Hecht
Publikováno v:
Haematologica, Vol 105, Iss 5 (2020)
Sepsis causes an activation of the human contact system, an inflammatory response mechanism against foreign surfaces, proteins and pathogens. The serine proteases of the contact system, factor XII and plasma kallikrein, are decreased in plasma of sep
Externí odkaz:
https://doaj.org/article/c9b6d71a7980459191b8df8179aeef1d
Autor:
Rida Malik, Peng Liao, Ji Zhou, Rawaa Hussain, James Charles Fredenburgh, Lisa Hettrick, Alexey S Revenko, Jeffrey I. Weitz
Publikováno v:
Blood Advances.
Factor (F) XII knockdown attenuates catheter thrombosis in rabbits. Because histidine-rich glycoprotein (HRG) modulates FXIIa activity, we hypothesized that HRG depletion would promote catheter thrombosis. To test this, rabbits were given antisense o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a49af3feeea1141bb6e9e6a68f6a756
https://doi.org/10.1182/bloodadvances.2022009236
https://doi.org/10.1182/bloodadvances.2022009236
Autor:
James W. Welsh, Maria Angelica Cortez, Alexey S. Revenko, Hadi Maazi, Meidi Gu, Fatemeh Masrorpour, Dawei Chen, Lisa Hettrick, Morgan Maureen Green, Natalie Wall Fowlkes, Claudia S. Kettlun Leyton, Liangpeng Yang, Carola Leuschner, Jie Zhang, Genevieve Bertolet, Mark D. Wasley, Duygu Sezen, Yun Hu, Nahum Puebla-Osorio, Hampartsoum B. Barsoumian, Kewen He
Supplementary Figures and Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dd53f1cd8e2a3b7cf6692f53981db11
https://doi.org/10.1158/2326-6066.22551861
https://doi.org/10.1158/2326-6066.22551861
