Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Alexey Palamarchuk"'
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/a6959298aa14467e9bb8f0ba1b05e57a
Autor:
Carlo M. Croce, Thomas Kipps, John P. Hagan, George A. Calin, Laura Rassenti, Chang-Gong Liu, Hansjuerg Alder, Stefano Volinia, Vadim Maximov, Alexey Efanov, Alexey Palamarchuk, Amelia Cimmino, Urmila Santanam, Yuri Pekarsky
PDF file, 654KB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af2248d78058d77d93e4165e3058b0b6
https://doi.org/10.1158/0008-5472.22368464
https://doi.org/10.1158/0008-5472.22368464
Autor:
Carlo M. Croce, Thomas Kipps, John P. Hagan, George A. Calin, Laura Rassenti, Chang-Gong Liu, Hansjuerg Alder, Stefano Volinia, Vadim Maximov, Alexey Efanov, Alexey Palamarchuk, Amelia Cimmino, Urmila Santanam, Yuri Pekarsky
B-cell chronic lymphocytic leukemia (B-CLL) is the most common human leukemia in the world. Deregulation of the TCL1 oncogene is a causal event in the pathogenesis of the aggressive form of this disease as was verified by using animal models. To stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e6b405560a65b6341d3f41e0259b39
https://doi.org/10.1158/0008-5472.c.6495971.v1
https://doi.org/10.1158/0008-5472.c.6495971.v1
Autor:
Carlo M. Croce, Thomas Kipps, John P. Hagan, George A. Calin, Laura Rassenti, Chang-Gong Liu, Hansjuerg Alder, Stefano Volinia, Vadim Maximov, Alexey Efanov, Alexey Palamarchuk, Amelia Cimmino, Urmila Santanam, Yuri Pekarsky
PDF file, 6KB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d56d278436b5e609b005e1098324ef
https://doi.org/10.1158/0008-5472.22368461
https://doi.org/10.1158/0008-5472.22368461
Autor:
Carlo M. Croce, Thomas Kipps, John P. Hagan, George A. Calin, Laura Rassenti, Chang-Gong Liu, Hansjuerg Alder, Stefano Volinia, Vadim Maximov, Alexey Efanov, Alexey Palamarchuk, Amelia Cimmino, Urmila Santanam, Yuri Pekarsky
PDF file, 22KB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39b881a099194e06d9e61da7af61e0d7
https://doi.org/10.1158/0008-5472.22368458.v1
https://doi.org/10.1158/0008-5472.22368458.v1
Autor:
Alexey Palamarchuk
Publikováno v:
E3S Web of Conferences, Vol 244, p 11005 (2021)
One of the most important areas of innovative development of economic systems of Russian regions is the formation of clusters. The global changes occurring in the innovation economy within the framework of the Fourth Industrial Revolution predetermin
Autor:
Luca Malcovati, Michael A. Caligiuri, Mark D. Minden, Anna Gallì, Narmin Ibrahimova, Rosario Distefano, Alexey Palamarchuk, Francesca Lovat, Pierluigi Gasparini, Silvia Catricalà, Tatsuya Nakamura, Paolo Fadda, Giovanni Nigita, Carlo M. Croce, Luisa Tomasello
Publikováno v:
Proc Natl Acad Sci U S A
Double knockout of the two miR-15/16 loci in mouse resulted in the development of acute myeloid leukemia (AML). This result suggested that, at least, a fraction of human AMLs could be due to a similar mechanism. We analyzed the role of the two miR-15
Autor:
Karl J. Smalley, Ruiyan Jing, Sili Fan, Carlo M. Croce, Guidantonio Malagoli Tagliazucchi, Louise Y.Y. Fong, Oliver Fiehn, Joseph Altemus, Cristian Taccioli, Kay Huebner, Alexey Palamarchuk, John L. Farber
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 117, iss 11
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance ESCC is a deadly disease with few prevention or treatment options. In a dietary Zn deficiency-promoted rat ESCC model with miR-31–controlled inflammation pathway up-regulation, systemic antimiR-31 reduces miR-31 level and inflammation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0b9f7bf86c61ecc8eb7556a592d2aa8
http://hdl.handle.net/11577/3339098
http://hdl.handle.net/11577/3339098
Autor:
Francesca Lovat, Marius Bill, Pierluigi Gasparini, Diana Sacchi, Matteo Fassan, Alexey Palamarchuk, Adrienne M. Dorrance, Giovanni Nigita, Parvathi Ranganathan, Ramiro Garzon, Rosario Distefano, Malith Karunasiri, Carlo M. Croce, Dario Veneziano
Publikováno v:
Proceedings of the National Academy of Sciences. 115:13069-13074
MicroRNAs (miRNAs) have been extensively reported to be associated with hematological malignancies. The loss of miR-15a/16–1 at chromosome 13q14 is a hallmark of most of human chronic lymphocytic leukemia (CLL). Deletion of murine miR-15a/16–1 an
Autor:
Paolo Fadda, Yuri Pekarsky, Alexey Palamarchuk, Luisa Tomasello, Emanuela M. Ghia, Carlo M. Croce, Veronica Balatti, Laura Z. Rassenti, George F. Widhopf, Thomas J. Kipps
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 114, iss 40
Loss of miR-15/16 is the most common genetic lesion in chronic lymphocytic leukemia (CLL), promoting overexpression of BCL2, which factors in leukemia pathogenesis. Indeed, an inhibitor of Bcl2, venetoclcax, is highly active in the treatment of patie