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Design principles of nuclear receptor signaling: how complex networking improves signal transduction
Autor:
Alexey N Kolodkin, Frank J Bruggeman, Nick Plant, Martijn J Moné, Barbara M Bakker, Moray J Campbell, Johannes P T M van Leeuwen, Carsten Carlberg, Jacky L Snoep, Hans V Westerhoff
Publikováno v:
Molecular Systems Biology, Vol 6, Iss 1, Pp 1-14 (2010)
Abstract The topology of nuclear receptor (NR) signaling is captured in a systems biological graphical notation. This enables us to identify a number of ‘design’ aspects of the topology of these networks that might appear unnecessarily complex or
Externí odkaz:
https://doaj.org/article/f2b210373e1d4c64b882cf37bd83e411
