Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Alexey N, Tomilin"'
Autor:
Daria Kriger, Uliana I. Podenkova, Evgeny I. Bakhmet, Evgenii Potapenko, Elena Ivanova, Alexey N. Tomilin, Anna S. Tsimokha
Publikováno v:
Cells, Vol 13, Iss 16, p 1362 (2024)
Embryonic stem cells (ESCs) are remarkable for the high activity level of ubiquitin–proteasome system—the molecular machinery of protein degradation in the cell. Various forms of the proteasome complexes comprising different subunits and interact
Externí odkaz:
https://doaj.org/article/ad6f968a823c4ec48ed6ab760e429e8d
Autor:
Sergey A. Sinenko, Alexey N. Tomilin
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2024)
Pluripotent stem cells of the mammalian epiblast and their cultured counterparts—embryonic stem cells (ESCs) and epiblast stem cells (EpiSCs)—have the capacity to differentiate in all cell types of adult organisms. An artificial process of reacti
Externí odkaz:
https://doaj.org/article/6c55aab0d1804648838e1ce476f6fd8f
Autor:
Igor B. Nazarov, Danil S. Zilov, Mikhail N. Gordeev, Evgenii V. Potapenko, Nataliya Yeremenko, Alexey N. Tomilin
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 123 (2024)
BOB1, a mammalian lymphocyte-specific transcriptional coactivator of the transcription factors OCT1 and OCT2 (OCT1/2), plays important roles in normal immune responses, autoimmunity, and hematologic malignancies. The issue of a DNA sequence preferenc
Externí odkaz:
https://doaj.org/article/86ba6fd9a0b047ca8a1ad0e2e8cbdffe
Autor:
Evgeny I. Bakhmet, Alexey N. Tomilin
Publikováno v:
Open Biology, Vol 12, Iss 11 (2022)
Externí odkaz:
https://doaj.org/article/e12922b07aca4ca1b805c779df308535
Autor:
Evgeny I. Bakhmet, Alexey N. Tomilin
Publikováno v:
Open Biology, Vol 12, Iss 6 (2022)
POUV is a relatively newly emerged class of POU transcription factors present in jawed vertebrates (Gnathostomata). The function of POUV-class proteins is inextricably linked to zygotic genome activation (ZGA). A large body of evidence now extends th
Externí odkaz:
https://doaj.org/article/a2e6a9f63ecf4900b5487732f5c44292
Autor:
Andrey A. Kuzmin, Veronika V. Ermakova, Sergey A. Sinenko, Sergey V. Ponomartsev, Tatiana Y. Starkova, Elena V. Skvortsova, Olga Cherepanova, Alexey N. Tomilin
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-10 (2019)
Abstract Background Methods based on site-specific recombinases are widely used in studying gene activities in vivo and in vitro. In these studies, constitutively active or inducible variants of these recombinases are expressed under the control of e
Externí odkaz:
https://doaj.org/article/20210ca284fe45e29f0f0e8cc2e092a9
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Reactive oxygen species (ROS), superoxide anion and hydrogen peroxide, are generated as byproducts of oxidative phosphorylation in the mitochondria or via cell signaling-induced NADPH oxidases in the cytosol. In the recent two decades, a plethora of
Externí odkaz:
https://doaj.org/article/c0c9a732321443b3bb45c82937552dbb
Autor:
Anna S. Tsimokha, Tatiana O. Artamonova, Egor E. Diakonov, Mikhail A. Khodorkovskii, Alexey N. Tomilin
Publikováno v:
Molecules, Vol 25, Iss 15, p 3504 (2020)
The ubiquitin-proteasome system (UPS) is one of the major protein degradation pathways in eukaryotic cells. Abnormal functioning of this system has been observed in cancer and neurological diseases. The 20S proteasomes, essential components of the UP
Externí odkaz:
https://doaj.org/article/363bf6cbb5bb48acb5a31066cbde3f1e
Autor:
Sergey V. Ponomartsev, Sergey A. Sinenko, Elena V. Skvortsova, Mikhail A. Liskovykh, Ivan N. Voropaev, Maria M. Savina, Andrey A. Kuzmin, Elena Yu. Kuzmina, Alexandra M. Kondrashkina, Vladimir Larionov, Natalay Kouprina, Alexey N. Tomilin
Publikováno v:
Cells, Vol 9, Iss 4, p 879 (2020)
Human artificial chromosomes (HACs), including the de novo synthesized alphoidtetO-HAC, are a powerful tool for introducing genes of interest into eukaryotic cells. HACs are mitotically stable, non-integrative episomal units that have a large transge
Externí odkaz:
https://doaj.org/article/4f5e0539ddb941dbb6193eff810f3d45
Autor:
Andrey A. Kuzmin, Alexey N. Tomilin
Publikováno v:
International journal of molecular sciences. 24(1)
Tools developed in the fields of genome engineering, precise gene regulation, and synthetic gene networks have an increasing number of applications. When shared with the scientific community, these tools can be used to further unlock the potential of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba7cf86f5fd6016385365f950261479
https://pubmed.ncbi.nlm.nih.gov/36613839
https://pubmed.ncbi.nlm.nih.gov/36613839