Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Alexey M. Petrov"'
Autor:
Marat A. Mukhamedyarov, Aydar N. Khabibrakhmanov, Venera F. Khuzakhmetova, Arthur R. Giniatullin, Guzalia F. Zakirjanova, Nikita V. Zhilyakov, Kamilla A. Mukhutdinova, Dmitry V. Samigullin, Pavel N. Grigoryev, Andrey V. Zakharov, Andrey L. Zefirov, Alexey M. Petrov
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 9022 (2023)
Amyotrophic lateral sclerosis (ALS) is manifested as skeletal muscle denervation, loss of motor neurons and finally severe respiratory failure. Mutations of RNA-binding protein FUS are one of the common genetic reasons of ALS accompanied by a ‘dyin
Externí odkaz:
https://doaj.org/article/af35ecf2af524f4bb276aa920301e7fb
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 1771 (2022)
For effective transmission of excitation in neuromuscular junctions, the postsynaptic response amplitude must exceed a critical level of depolarization to trigger action potential spreading along the muscle-fiber membrane. At the presynaptic level, t
Externí odkaz:
https://doaj.org/article/cac730a1793d48a6a1f1fe9fcc6f103a
Autor:
Irina G. Bryndina, Maria N. Shalagina, Vladimir A. Protopopov, Alexey V. Sekunov, Andrey L. Zefirov, Guzalia F. Zakirjanova, Alexey M. Petrov
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2239 (2021)
Muscle disuse and denervation leads to muscle atrophy, but underlying mechanisms can be different. Previously, we have found ceramide (Cer) accumulation and lipid raft disruption after acute hindlimb suspension (HS), a model of muscle disuse. Herein,
Externí odkaz:
https://doaj.org/article/3ecaef4e3c704860b435c9ba054a67f3
Autor:
Alexey M. Petrov, Maria N. Shalagina, Vladimir A. Protopopov, Valeriy G. Sergeev, Sergey V. Ovechkin, Natalia G. Ovchinina, Alexey V. Sekunov, Andrey L. Zefirov, Guzalia F. Zakirjanova, Irina G. Bryndina
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 19, p 4860 (2019)
Lipid raft disruption is an early event during skeletal muscle unloading. Ceramide (Cer) serves as a signaling lipid that can contribute to lipid raft disturbance and muscle atrophy. Using biochemical and fluorescent approaches, the distribution of C
Externí odkaz:
https://doaj.org/article/9883d7459c674e2f9beae4527bbd8a24
Autor:
Igor I. Krivoi, Alexey M. Petrov
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 5, p 1046 (2019)
A present review is devoted to the analysis of literature data and results of own research. Skeletal muscle neuromuscular junction is specialized to trigger the striated muscle fiber contraction in response to motor neuron activity. The safety factor
Externí odkaz:
https://doaj.org/article/256bda2928da4361abe22f39d7163f5e
Publikováno v:
Cellular and Molecular Neurobiology. 43:729-739
Publikováno v:
Free Radical Biology and Medicine. 174:121-134
Inflammatory reactions induce changes in the neuromuscular system. The mechanisms underlying this link are unclear. Besides cytokines and reactive oxygen species (ROS), production of an antiviral oxysterol 25-hydroxycholesterol (25HC) by immune cells
Publikováno v:
Nevrologiâ, Nejropsihiatriâ, Psihosomatika, Vol 13, Iss 1S, Pp 69-72 (2021)
The spread of the COVID-19 pandemic posed a serious challenge for scientific and clinical medical institutions in terms of research for new multiple sclerosis (MS) treatments. In this review we discuss the associations between coronavirus infection a
Publikováno v:
Neurotherapeutics
Cholesterol and 24-hydroxycholesterol are the most abundant brain sterols and represent the substrate and product, respectively, of cytochrome P450 46A1 (CYP46A1), a CNS-specific enzyme. CYP46A1 controls cholesterol elimination and turnover in the br
Autor:
Y. G. Odnoshivkina, Alexey M. Petrov
Publikováno v:
Journal of Evolutionary Biochemistry and Physiology. 57:527-541
One of the important mechanisms of cardiac regulation is realized via sympathetic innervation of cardiac myocytes. Axons of the sympathetic neurons branch out and form varicosities along their length, filled with synaptic vesicles that contain a majo